Nuclear Overhauser Effect and Computational Characterization of the β-Spiral of the Polypentapeptide of Elastin

1989 ◽  
Vol 6 (5) ◽  
pp. 851-858 ◽  
Author(s):  
D. K. Chang ◽  
C. M. Venkatachalam ◽  
K. U. Prasad ◽  
D. W. Urry
Keyword(s):  
Nuclear Overhauser Effect ◽  
Overhauser Effect ◽  
Polypentapeptide Of Elastin ◽  
Nuclear Overhauser

scholarly journals Characterization of Halogen Bonded Adducts in Solution by Advanced NMR Techniques

2017 ◽  
Author(s):  
Gianluca Ciancaleoni
Keyword(s):  
Nuclear Overhauser Effect ◽  
Halogen Bonding ◽  
X Ray Crystallography ◽  
Diffusion Nmr ◽  
Overhauser Effect ◽  
Crucial Information ◽  
Nmr Techniques ◽  
Nuclear Overhauser ◽  
And Diffusion

In the last 20 years, a huge amount of experimental results about halogen bonding (XB) has been produced. Most of the systems have been characterized by solid state X-ray crystallography, whereas in solution the only routine technique is the titration (by using 1H and 19F NMR, IR, UV-Vis or Raman spectroscopies, depending on the nature of the system), with the aim of characterizing the strength of the XB interaction. Unfortunately, the titration techniques have many intrinsic limitations and they should be coupled with other, more sophisticated techniques to have an accurate and detailed description of the geometry and stoichiometry of the XB adduct in solution. In this review, it will be shown how crucial information about XB adducts can be obtained by advanced NMR techniques, as Nuclear Overhauser Effect-based Spectroscopies (NOESY, ROESY, HOESY…) and diffusion NMR techniques (PGSE or DOSY).

Synthesis and 2D NMR characterization of Ni(II), Pd(II), and Cu(II) complexes with H2cdsalen (methyl-2{N-[2-(2′-hydroxyphenyl)methylidenenitrilo]ethyl}amino-1-cyclopentenedithiocarboxylate)

2012 ◽  
Vol 90 (3) ◽  
pp. 237-242
Author(s):  
T.J. Morales-Juárez ◽  
M.C. Sánchez-López ◽  
R.M. Gómez-Espinosa ◽  
I. García-Orozco ◽  
D. Corona-Becerril
Keyword(s):  
Nuclear Overhauser Effect ◽  
2D Nmr ◽  
Conformational Studies ◽  
Overhauser Effect ◽  
Nmr Characterization ◽  
Nuclear Overhauser ◽  
2D Roesy

In this study we report on the preparation of Ni(II), Pd(II), Co(II), and Cu(II) complexes with H2cdsalen (methyl-2{N-[2-(2′-hydroxyphenyl)methylidenenitrilo]ethyl}amino-1-cyclopentenedithiocarboxylate)salicylaldehyde. The products were characterized using 1D NMR (1H and 13C) and 2D NMR (COSY, NOESY, and ROESY) techniques. The conformational studies of the complexes with Ni and Pd in solution have been performed with help of the nuclear Overhauser effect (NOE) and 2D ROESY experiments.

Characterization of Helix Terminating Schellman Motifs in Peptides. Crystal Structure and Nuclear Overhauser Effect Analysis of a Synthetic Heptapeptide Helix

1997 ◽  
Vol 119 (39) ◽  
pp. 9246-9251 ◽  
Author(s):  
Saumen Datta ◽  
N. Shamala ◽  
Arindam Banerjee ◽  
Animesh Pramanik ◽  
Surajit Bhattacharjya ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Nuclear Overhauser Effect ◽  
Effect Analysis ◽  
Overhauser Effect ◽  
Nuclear Overhauser

1H NMR studies of [N-MeAib1, Tyr(Me)4]ANGII and [N-MeAib1, Tyr(Me)4, Ile8]ANGII in dimethylsulfoxide by nuclear Overhauser effect (NOE) enhancement spectroscopy: cis-trans Isomerism of the His-Pro bond

1990 ◽  
Vol 55 (4) ◽  
pp. 1106-1111 ◽  
Author(s):  
John Matsoukas ◽  
Paul Cordopatis ◽  
Raghav Yamdagni ◽  
Graham J. Moore
Keyword(s):  
1H Nmr ◽  
Nuclear Overhauser Effect ◽  
Nmr Studies ◽  
Restricted Rotation ◽  
Overhauser Effect ◽  
Major Isomer ◽  
Conformational Properties ◽  
Nuclear Overhauser

The conformational properties of the Sarmesin analogues [N-MeAib1, Tyr(Me)4]ANGII and [N-MeAib1, Tyr(Me)4, Ile8]ANGII in hexadeutero-dimethysulfoxide were investigated by Nuclear Overhauser Effect (NOE) Enhancement Studies. Cis-trans isomers (ratio 1 : 6) due to restricted rotation of the His-Pro bond were observed. Interresidue interactions between the His Cα proton and the two Pro Cδ protons revealed that the major isomer was the trans.

scholarly journals Cylindromicin from Arctic-Derived Fungus Tolypocladium sp. SCSIO 40433

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1080
Author(s):  
Imran Khan ◽  
Jing Peng ◽  
Zhuangjie Fang ◽  
Wei Liu ◽  
Wenjun Zhang ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Nuclear Overhauser Effect ◽  
Inhibition Activity ◽  
Tyrosinase Inhibition ◽  
Bioactive Natural Products ◽  
Chemical Structures ◽  
Overhauser Effect ◽  
Spectroscopic Analyses ◽  
Potential Resource ◽  
Nuclear Overhauser

The fungus strain SCSIO 40433 was isolated from an Arctic-derived glacier sediment sample and characterized as Tolypocladium cylindrosporum. A new compound, cylindromicin (1), and seven known secondary metabolites (2–8) were isolated from this strain. The chemical structures of these compounds were elucidated by comprehensive spectroscopic analyses. Cylindromicin (1) featured a 3,4-dihydro-2H-pyran skeleton. The absolute configuration of compound 1 was assigned via interpretation of key Nuclear Overhauser Effect Spectroscopy (NOESY) correlations and Electronic Circular Dichroism (ECD) calculation. Cylindromicin (1) exhibited significant tyrosinase inhibition activity. This study highlights Polar fungi as a potential resource for new bioactive natural products.

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