Synthesis and spectroscopic characterization of new sulfanilamide-functionalized magnetic nanoparticles, and the usability for carbonic anhydrase purification: is there perspective for ‘cancer treatment’ application?

AbstractPotential application of magnetic nanoparticles as drug carriers in medical treatment requires prior determination of their effects on cells. In this work different spin labels and magnetic nanoparticles functionalized with spin labels as well as their interaction with yeast cells were investigated using electron spin resonance (ESR) method. ESR was demonstrated to be a suitable method for monitoring of magnetic core and attached spin labels. Particular emphasis was placed on characterization of endocytosis and redox processes running inside the cell, resulting in recombination of spin labels. Such data could only be obtained at reduced temperature of ESR measurements.

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Solvo-thermal synthesis, characterization of aluminon-functionalized magnetic nanoparticles and investigation of its adsorption performance for Cr(VI) and Cr(III)

Journal of the Taiwan Institute of Chemical Engineers ◽

10.1016/j.jtice.2015.04.023 ◽

2015 ◽

Vol 55 ◽

pp. 180-188 ◽

Cited By ~ 12

Author(s):

Amr A. Yakout ◽

Hassan M. Albishri

Keyword(s):

Magnetic Nanoparticles ◽

Thermal Synthesis ◽

Adsorption Performance ◽

Functionalized Magnetic Nanoparticles

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Preparation and characterization of iminodiacetic acid-functionalized magnetic nanoparticles and its selective removal of bovine hemoglobin

Nanotechnology ◽

10.1088/0957-4484/22/6/065705 ◽

2011 ◽

Vol 22 (6) ◽

pp. 065705 ◽

Cited By ~ 27

Author(s):

Min Zhang ◽

Xiwen He ◽

Langxing Chen ◽

Yukui Zhang

Keyword(s):

Magnetic Nanoparticles ◽

Iminodiacetic Acid ◽

Selective Removal ◽

Bovine Hemoglobin ◽

Functionalized Magnetic Nanoparticles

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Kinetic and Spectroscopic Characterization of the Gamma-Carbonic Anhydrase from the MethanoarchaeonMethanosarcina thermophila†

Biochemistry ◽

10.1021/bi9828876 ◽

1999 ◽

Vol 38 (40) ◽

pp. 13119-13128 ◽

Cited By ~ 60

Author(s):

Birgit E. Alber ◽

Christopher M. Colangelo ◽

Jun Dong ◽

Christina M. V. Stålhandske ◽

Teaster T. Baird ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Spectroscopic Characterization ◽

Gamma Carbonic Anhydrase

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Spectroscopic Characterization of an Oxovanadium(IV) Complex of Oxodiacetic Acid and 2,2’-Bipyridine. Bioactivity on Osteoblast-Like Cells in Culture

Journal of the Mexican Chemical Society ◽

10.29356/jmcs.v57i3.204 ◽

2017 ◽

Vol 57 (3) ◽

Author(s):

Ignacio E. León ◽

Susana B. Etcheverry ◽

Beatriz S. Parajón-Costa ◽

Enrique J. Baran

Keyword(s):

Cell Proliferation ◽

Biological Activity ◽

Cancer Treatment ◽

Cellular Proliferation ◽

Spectroscopic Characterization ◽

Cells In Culture ◽

Mouse Calvaria ◽

Tumoral Cells

The oxovanadium(IV) complex of oxodiacetic acid (H2ODA) and 2,2’-bipyridine (bipy) of stoichiometry [VO(ODA)(bipy)]⋅H2O, was thoroughly characterized by infrared, Raman and electronic spectroscopies. The biological activity of the complex on the cell proliferation was tested on osteoblast-like cells (MC3T3E1 osteoblastic mouse calvaria-derived cells and UMR106 rat osteosarcoma-derived cells) in culture. The complex caused inhibition of cellular proliferation in both osteoblast-like cells in culture, but its action was statistically stronger in the tumoral cells. This effect was specially marked with increasing concentrations of the complex. Based on these preliminary biological results, [VO(ODA)(bipy)]⋅H2O can be considered as a good candidate to be further investigated in relation to cancer treatment.

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