On the binding reaction of loratadine with human serum acute phase protein alpha 1-acid glycoprotein

2021 ◽  
pp. 1-8
Author(s):  
Fahad M. Almutairi ◽  
Mohammad Rehan Ajmal ◽  
Mohammad Khursheed Siddiqi ◽  
Adel I. Alalawy ◽  
Rizwan Hasan Khan
Keyword(s):  
Human Serum ◽  
Acute Phase ◽  
Acute Phase Protein ◽  
Binding Reaction ◽  
Acid Glycoprotein ◽  
Phase Protein

Kinetics of endotoxin-induced acute-phase protein gene expression and its modulation by TNF-alpha monoclonal antibody

1992 ◽  
Vol 262 (5) ◽  
pp. R786-R793 ◽  
Author(s):  
R. J. Sharma ◽  
D. C. Macallan ◽  
P. Sedgwick ◽  
D. G. Remick ◽  
G. E. Griffin
Keyword(s):  
Gene Expression ◽  
Monoclonal Antibody ◽  
Acute Phase ◽  
Protein Gene ◽  
Acute Phase Protein ◽  
Plasma Concentrations ◽  
Tnf Alpha ◽  
Acid Glycoprotein ◽  
Phase Protein ◽  
Kinetics Of

The kinetics of cytokine release and acute-phase protein gene expression in liver were investigated in rats receiving a single intraperitoneal bolus dose of Escherichia coli lipopolysaccharide (LPS). Transient elevation of plasma tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) were detected. Hepatic messenger RNAs for two acute-phase proteins, alpha 1-acid glycoprotein and alpha 2-macroglobulin, were measured by Northern blotting and were found to increase to a maximum at 24 h, returning to normal by 72 h; plasma concentrations showed a slower but more sustained rise. For albumin, hepatic mRNA was reduced, being minimum at 24 h with a similar but more prolonged fall in plasma concentration. Pretreatment of rats with TNF-alpha monoclonal antibody 4 h before LPS ameliorated weight loss and anorexia, partially suppressed the rise in IL-6 and reduced the increase in hepatic mRNA and plasma concentrations of alpha 1-acid glycoprotein and alpha 2-macroglobulin. For albumin, however, such pretreatment had no effect on the fall in either hepatic mRNA or plasma concentration. Thus we have defined an in vivo role of TNF-alpha in the control of endotoxin-induced acute-phase protein generation.

scholarly journals Decreased sialylation of the acute phase protein α1-acid glycoprotein in feline infectious peritonitis (FIP)

2004 ◽  
Vol 99 (3-4) ◽  
pp. 229-236 ◽  
Author(s):  
Fabrizio Ceciliani ◽  
Claudia Grossi ◽  
Alessia Giordano ◽  
Vanessa Pocacqua ◽  
Saverio Paltrinieri
Keyword(s):  
Acute Phase ◽  
Acute Phase Protein ◽  
Feline Infectious Peritonitis ◽  
Acid Glycoprotein ◽  
Phase Protein

scholarly journals Acute phase protein, α – 1- acid glycoprotein (AGP-1), has differential effects on TLR-2 and TLR-4 mediated responses

Immunobiology ◽  
2019 ◽  
Vol 224 (5) ◽  
pp. 672-680 ◽  
Author(s):  
Mosale Seetharam Sumanth ◽  
Kandahalli Venkataranganayaka Abhilasha ◽  
Shancy Petsel Jacob ◽  
Vyala Hanumanthareddy Chaithra ◽  
Venkatesha Basrur ◽  
...  
Keyword(s):  
Acute Phase ◽  
Acute Phase Protein ◽  
Differential Effects ◽  
Acid Glycoprotein ◽  
Phase Protein

The bovine acute phase protein α1-acid glycoprotein (AGP) can disrupt Staphylococcus aureus biofilm

2019 ◽  
Vol 235 ◽  
pp. 93-100 ◽  
Author(s):  
Gabriele Meroni ◽  
Valentina Zamarian ◽  
Cristina Prussiani ◽  
Valerio Bronzo ◽  
Cristina Lecchi ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Acute Phase ◽  
Acute Phase Protein ◽  
Acid Glycoprotein ◽  
Phase Protein

α1-Acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties

2003 ◽  
Vol 14 (1) ◽  
pp. 25-34 ◽  
Author(s):  
Tino Hochepied ◽  
Franklin G Berger ◽  
Heinz Baumann ◽  
Claude Libert
Keyword(s):  
Acute Phase ◽  
Acute Phase Protein ◽  
Acid Glycoprotein ◽  
Phase Protein
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