Treatment adherence to psychotropic drugs among non-Western migrants: a systematic review

The use of psychotropic drugs to treat problems of everyday life is a growing phenomenon in many countries. A systematic review was conducted as a method of synthesis of results of the qualitative primary studies developed to explore the perspective of health professionals and patients regarding the use of psychotropic drugs to overcome personal problems. This systematic review was conducted in the databases Medline (PubMed), Central (Cochrane), Psycoinfo and Lilacs, including gray literature and manual search (june/2015). We identified 581 publications that were evaluated in stages and 26 met the inclusion criteria with a total of 876 participants including health professionals and patients. The doctors showed empathy by prescribing. The health professionals-prescribers and non-prescribers-were concerned about the dependence of patients on the psychotropic and the pressure to prescribe. Patients felt unable to solve their problems and seek medications as a solution. The psychotropics were considered a useful resource to overcome the social problems, existing denial of its side effects as well as the lack of openness and access to other support mechanisms.

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Comparative Utility of Acupuncture and Western Medication in the Management of Perimenopausal Insomnia: A Systematic Review and Meta-Analysis

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2021/5566742 ◽

2021 ◽

Vol 2021 ◽

pp. 1-16

Author(s):

Fei-Yi Zhao ◽

Qiang-Qiang Fu ◽

Gerard A. Kennedy ◽

Russell Conduit ◽

Wen-Zhong Wu ◽

...

Keyword(s):

Systematic Review ◽

Psychotropic Drugs ◽

Quality Index ◽

Pittsburgh Sleep Quality Index ◽

Meta Analysis ◽

Hormone Replacement ◽

Controlled Trials ◽

Limited Evidence ◽

Randomized Controlled ◽

Kupperman Index

Background. Many women with perimenopausal insomnia (PMI) have sought alternative therapies such as acupuncture because of concerns about risks associated with hormone replacement therapy (HRT) and/or psychotropic drugs. This systematic review aimed to clarify if acupuncture alone or combined with standard Western pharmacotherapy (HRT and/or psychotropic drugs) is more effective in ameliorating PMI in comparison to pharmacotherapy alone. Methods. Randomized controlled trials (RCTs) of PMI treatment via acupuncture alone or combined with Western pharmacotherapy versus Western pharmacotherapy were searched for from eleven databases from inception to March 2020. Cochrane criteria were followed. Results. Fifteen studies involving 1410 women were analyzed. Meta-analysis indicated that acupuncture significantly reduced the global scores of Pittsburgh Sleep Quality Index (PSQI) [MD = −2.38, 95% CI (−3.38, −1.37), p < 0.01] and Kupperman Index [MD = −5.95, 95% CI (−10.68, −1.21), p = 0.01], compared with hypnotics. Acupuncture combined with hypnotics was more effective than hypnotics alone in decreasing PSQI scores [MD = −3.13, 95% CI (−5.43, −0.83), p < 0.01]. Too few RCTs were available to investigate the clinical efficacy differences between acupuncture and HRT/psychotropic drugs other than hypnotics. Conclusions. Despite limited evidence, in comparison to hypnotics, acupuncture was associated with significant improvements in PMI, and reductions of other menopausal symptoms. This finding suggests that acupuncture may be a useful addition to treatment for PMI.

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Psychosocial interventions to improve HIV treatment adherence: A systematic review

10.31234/osf.io/a5pcj ◽

2021 ◽

Author(s):

Stefanella Costa-Cordella ◽

Alejandra Rossi ◽

Aitana Grasso-Cladera ◽

Javiera Duarte ◽

Claudia P. Cortes

Keyword(s):

Systematic Review ◽

Treatment Adherence ◽

Peer Support ◽

Psychosocial Interventions ◽

Hiv Treatment ◽

People Living With Hiv ◽

Individual Counselling ◽

Suboptimal Adherence ◽

Study Designs

Introduction: The problem of suboptimal adherence to antiretroviral treatment (ART) can be overcome through multidisciplinary management that includes evidence-based psychosocial interventions. Existing reviews focus only on randomized controlled trials, overlooking valuable interventions whose evidence comes from different study designs. This review aimed to synthesize the current state of the art in psychological interventions for ART adherence, integrating studies with a variety of research designs.Methods: We conducted a systematic review following PRISMA guidelines. We searched five databases for articles reporting a psychosocial intervention to improve treatment adherence for people living with HIV. The quality of each study was analyzed, and the data summarized using a narrative synthesis method.Results and discussion: Twenty-six articles were identified for inclusion. Individual counselling was the most common intervention, followed by peer-support based interventions delivered virtually or in person. Most interventions mixed different strategies, combining technology with individual counselling and peer support. It is important to note that the quality of evidence was not dependent on the study design.Conclusion: While the evidence requires further advancement, the review provides insight into which psychosocial interventions are helpful in improving ART treatment adherence.

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PIN40 MANAGEMENT OF HIV/AIDS IN BRAZIL: A SYSTEMATIC REVIEW ON TREATMENT ADHERENCE AND ITS IMPACT ON RESOURCE UTILIZATION AND COSTS

Value in Health ◽

10.1016/j.jval.2020.04.512 ◽

2020 ◽

Vol 23 ◽

pp. S175

Author(s):

T. Decimoni ◽

R.A. Fernandes ◽

F. Ferrarezzo ◽

V.D. Zillmer ◽

J.T. Aquino

Keyword(s):

Systematic Review ◽

Treatment Adherence ◽

Resource Utilization ◽

Hiv Aids

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Systematic review of HIV treatment adherence research among people who inject drugs in the United States and Canada: evidence to inform pre-exposure prophylaxis (PrEP) adherence interventions

BMC Public Health ◽

10.1186/s12889-018-6314-8 ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 10

Author(s):

Angela R. Bazzi ◽

Mari-Lynn Drainoni ◽

Dea L. Biancarelli ◽

Joshua J. Hartman ◽

Matthew J. Mimiaga ◽

...

Keyword(s):

United States ◽

Systematic Review ◽

Treatment Adherence ◽

People Who Inject Drugs ◽

The United States ◽

Hiv Treatment ◽

Adherence Interventions ◽

Exposure Prophylaxis

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Social support and treatment adherence in patients with end‐stage renal disease: A systematic review

Seminars in Dialysis ◽

10.1111/sdi.12831 ◽

2019 ◽

Vol 32 (6) ◽

pp. 562-574 ◽

Cited By ~ 7

Author(s):

Helena Sousa ◽

Oscar Ribeiro ◽

Constança Paúl ◽

Elísio Costa ◽

Vasco Miranda ◽

...

Keyword(s):

Social Support ◽

Systematic Review ◽

Renal Disease ◽

Treatment Adherence ◽

End Stage Renal Disease ◽

Stage Renal Disease ◽

End Stage

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What are the effects of medication adherence interventions in rheumatic diseases: a systematic review

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-206593 ◽

2015 ◽

Vol 75 (4) ◽

pp. 667-673 ◽

Cited By ~ 42

Author(s):

Jessica S Galo ◽

Pavandeep Mehat ◽

Sharan K Rai ◽

Antonio Avina-Zubieta ◽

Mary A De Vera

Keyword(s):

Systematic Review ◽

Medication Adherence ◽

Treatment Adherence ◽

Rheumatic Diseases ◽

Inflammatory Arthritis ◽

Patient Characteristics ◽

Disease Outcome ◽

International Pharmaceutical Abstract ◽

Study Methodology ◽

Adherence Interventions

ObjectivesConsistent reports of suboptimal treatment adherence among patients with inflammatory arthritis underscore the importance of understanding how adherence can be promoted and supported. Our objectives were to identify and classify adherence interventions; and assess the evidence on the effects of adherence interventions on outcomes of patients with rheumatic diseases.MethodsWe conducted a mapped search of Medline, Embase and International Pharmaceutical Abstract databases to identify studies meeting inclusion criteria of: (1) patient population with inflammatory arthritis; (2) evaluation of an intervention or programme targeting medication adherence directly or indirectly; (3) reporting of one or more measures of medication adherence and disease outcome; (4) publication in English, French or Spanish. For our first objective, we applied a structured framework to classify interventions according target (patient vs provider), focus (educational vs behavioural vs affective), implementation (generalised vs tailored), complexity (single vs multifaceted) and provider. For the second objective, we appraised the evidence of effects of interventions on adherence and disease outcomes.ResultsWe identified 23 studies reporting adherence interventions that directly or indirectly addressed treatment adherence in rheumatic diseases and further appraised included RCTs. Interventions that were shown to impact adherence outcomes were generally interventions directed at adherence, tailored to patients and delivered by a healthcare provider. For interventions that were not shown to have impacts, reasons may be those related to the intervention itself, patient characteristics or study methodology.ConclusionsOur systematic review shows limited research on adherence interventions in rheumatic diseases with inconsistent impacts on adherence or disease outcome.

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