scholarly journals Microspheres Encapsulating Immunotherapy Agents Target the Tumor-Draining Lymph Node in Pancreatic Ductal Adenocarcinoma

2020 ◽  
Vol 49 (7) ◽  
pp. 808-823 ◽  
Author(s):  
Booyeon J. Han ◽  
Joseph D. Murphy ◽  
Shuyang Qin ◽  
Jian Ye ◽  
Taylor P. Uccello ◽  
...  
Keyword(s):  
Lymph Node ◽  
Pancreatic Ductal Adenocarcinoma ◽  
Ductal Adenocarcinoma ◽  
Draining Lymph Node ◽  
Tumor Draining Lymph Node

scholarly journals Cancer Cells Regulate Lymphocyte Recruitment and Leukocyte-Endothelium Interactions in the Tumor-Draining Lymph Node

2005 ◽  
Vol 65 (24) ◽  
pp. 11639-11648 ◽  
Author(s):  
Virginie Carrière ◽  
Renaud Colisson ◽  
Carine Jiguet-Jiglaire ◽  
Elisabeth Bellard ◽  
Gérard Bouche ◽  
...  
Keyword(s):  
Lymph Node ◽  
Cancer Cells ◽  
Draining Lymph Node ◽  
Tumor Draining Lymph Node

Targeting the Tumor-Draining Lymph Node With Adjuvant Nanoparticles for Cancer Immunotherapy

2013 ◽  
Author(s):  
Susan N. Thomas
Keyword(s):  
Drug Delivery ◽  
Lymph Node ◽  
Cancer Immunotherapy ◽  
Cancer Progression ◽  
Targeted Delivery ◽  
Immune Escape ◽  
Material Design ◽  
Draining Lymph Node ◽  
Clinical Interest ◽  
Tumor Draining Lymph Node

Immunotherapy-based approaches for cancer treatment are of increasing clinical interest. Principles of drug delivery and the emerging field of material design for immunomodulation might hold significant promise for novel approaches in cancer immunotherapy since biomaterials engineering strategies enable enhanced delivery of immune modulatory agents to tissues and cells of the immune system1. One tissue of significant clinical interest in a cancer setting is the tumor-draining lymph node (TDLN), which participates in cancer progression by enabling both metastatic dissemination as well as tumor-induced immune escape. Hence, the TDLN represents a novel target for drug delivery schemes for cancer immunotherapy. We hypothesize that targeted delivery of adjuvants (Adjs) to the TDLN using a biomaterials-based approach might promote antitumor immunity and hinder tumor growth.

Prognostic Relevance of Extracapsular Lymph Node Involvement in Pancreatic Ductal Adenocarcinoma

2009 ◽  
Vol 16 (11) ◽  
pp. 3070-3079 ◽  
Author(s):  
Gregory Sergeant ◽  
Nadine Ectors ◽  
Steffen Fieuws ◽  
Raymond Aerts ◽  
Baki Topal
Keyword(s):  
Lymph Node ◽  
Pancreatic Ductal Adenocarcinoma ◽  
Lymph Node Involvement ◽  
Ductal Adenocarcinoma ◽  
Prognostic Relevance ◽  
Node Involvement

Effect of Interleukin-l?? on the In Vitro Activation of Tumor-Draining Lymph Node Cells for Adoptive Immunotherapy

1994 ◽  
Vol 16 (1) ◽  
pp. 1-12
Author(s):  
James M. Hammel ◽  
Melissa K. Tuck ◽  
Jon M. Hain ◽  
Alfred E. Chang ◽  
Vernon K. Sondak
Keyword(s):  
Lymph Node ◽  
Adoptive Immunotherapy ◽  
In Vitro Activation ◽  
Lymph Node Cells ◽  
Draining Lymph Node ◽  
Tumor Draining Lymph Node

Activation by anti-CD3 of tumor-draining lymph node cells for specific adoptive immunotherapy

1991 ◽  
Vol 134 (2) ◽  
pp. 473-479 ◽  
Author(s):  
Hirohisa Yoshizawa ◽  
Keisuke Sakai ◽  
Alfred E. Chang ◽  
Suyu Shu
Keyword(s):  
Lymph Node ◽  
Adoptive Immunotherapy ◽  
Lymph Node Cells ◽  
Draining Lymph Node ◽  
Tumor Draining Lymph Node

Abstract 526: Tumor-draining lymph node irradiation reduces tumor-infiltrating stem-like CD8+T-cells and abrogates the abscopal effect

2019 ◽  
Author(s):  
Zachary S. Buchwald ◽  
Tahseen H. Nasti ◽  
Christiane S. Eberhardt ◽  
Andreas Wieland ◽  
David Lawson ◽  
...  
Keyword(s):  
T Cells ◽  
Lymph Node ◽  
Cd8 T Cells ◽  
Abscopal Effect ◽  
Draining Lymph Node ◽  
Tumor Draining Lymph Node ◽  
Lymph Node Irradiation
Sign in / Sign up

Export Citation Format

Share Document