Frozen-thawed blastocyst transfer in natural cycle increase implantation rates compared artificial cycle

2019 ◽  
Vol 35 (10) ◽  
pp. 873-877 ◽  
Author(s):  
Daniella Fernanda Cardenas Armas ◽  
Juana Peñarrubia ◽  
Anna Goday ◽  
Marta Guimerá ◽  
Ester Vidal ◽  
...  
1967 ◽  
Vol 37 (4) ◽  
pp. 385-391 ◽  
Author(s):  
S. J. MANTALENAKIS ◽  
M. M. KETCHEL

SUMMARY Five-day blastocysts were transferred to the uteri of rats during post-partum pseudopregnancy. Low implantation rates were observed when blastocysts were transferred on days 5 to 11 of lactation pseudopregnancy to recipients which were suckling their litters. Two incidents of asynchronous implantation occurred. If the suckling young were removed at the time of blastocyst transfer, high rates of implantation were obtained. If the cervix of the recipients was electrically stimulated at the time of the post-partum oestrus, implantation, while delayed, occurred at a high rate even though the recipients were suckling their litters. These results suggest that the cervical stimulation which occurs at copulation is a requirement for implantation in normally mated lactating rats.


2010 ◽  
Vol 94 (4) ◽  
pp. S162
Author(s):  
G.F. Celia ◽  
A. Botes ◽  
J.D. Gordon ◽  
M. DiMattina

2021 ◽  
Vol 116 (3) ◽  
pp. e164
Author(s):  
Alison T. Gruber ◽  
Amber M. Klimczak ◽  
Nola S. Herlihy ◽  
Brent M. Hanson ◽  
Julia G. Kim ◽  
...  

2018 ◽  
Vol 110 (4) ◽  
pp. e226
Author(s):  
J. Stewart ◽  
M. Irani ◽  
J. Chervenak ◽  
P. Chung ◽  
G. Schattman ◽  
...  

2011 ◽  
Vol 5 ◽  
pp. CMRH.S7735 ◽  
Author(s):  
Sherif F. Hendawy ◽  
TA Raafat

Background Extended in vitro embryo culture and blastocyst transfer have emerged as essential components of the advanced reproductive technology armamentarium, permitting selection of more advanced embryos considered best suited for transfer. Aim of study The aim of this study was to compare between cleavage stage and blastocyst stage embryo transfer in patients undergoing intracytoplasmic sperm injection, and to assess the role of assisted hatching technique in patients undergoing blastocyst transfer. Patients and methods This study was carried out on two groups. Group I: 110 patients who underwent 120 cycles of intracytoplasmic sperm injection with day 2-3 embryo transfer—for unexplained infertility or male factor within the previous 3 years. Their data obtained retrospectively from medical records. Group II: 46 age matched infertile female patients undergoing 51 intracytoplasmic sperm injection cycles for similar causes. Patients in Group II were further subdivided into 2 equal subgroups; Group Ila (23 patients), which had laser assisted hatching and Group IIb (23 patients), which did not have assisted hatching. All patients had an infertility workup including basal hormonal profile, pelvic ultrasound, hysterosalpingogram and/or laparoscope and semen analysis of the patient's partner. All patients underwent controlled ovarian hyperstimulation: Using long protocol of ovulation induction. Laser assisted hatching was done for blastocysts of 23 patients. Results Comparison between both groups as regards the reproductive outcome showed a significant difference in pregnancy and implantation rates, both being higher in group II ( P < 0.05) Comparison between both subgroups as regards the reproductive outcome showed a highly significant difference in pregnancy and implantation rates, both being higher in Group IIa ( P < 0.01). There was also a significantly higher rate of multiple pregnancies among Group IIa ( P < 0.05). Conclusion Blastocyst transfer is a successful and improved alternative for patients with multiple failed in vitro fertilization attempts, associated with a significant increase in pregnancy and implantation rates. Furthermore, laser assisted hatching increases implantation and clinical pregnancy rates.


2021 ◽  
Vol 12 ◽  
Author(s):  
Sezcan Mumusoglu ◽  
Mehtap Polat ◽  
Irem Yarali Ozbek ◽  
Gurkan Bozdag ◽  
Evangelos G. Papanikolaou ◽  
...  

Despite the worldwide increase in frozen embryo transfer, the search for the best protocol to prime endometrium continues. Well-designed trials comparing various frozen embryo transfer protocols in terms of live birth rates, maternal, obstetric and neonatal outcome are urgently required. Currently, low-quality evidence indicates that, natural cycle, either true natural cycle or modified natural cycle, is superior to hormone replacement treatment protocol. Regarding warmed blastocyst transfer and frozen embryo transfer timing, the evidence suggests the 6th day of progesterone start, LH surge+6 day and hCG+7 day in hormone replacement treatment, true natural cycle and modified natural cycle protocols, respectively. Time corrections, due to inter-personal differences in the window of implantation or day of vitrification (day 5 or 6), should be explored further. Recently available evidence clearly indicates that, in hormone replacement treatment and natural cycles, there might be marked inter-personal variation in serum progesterone levels with an impact on reproductive outcomes, despite the use of the same dose and route of progesterone administration. The place of progesterone rescue protocols in patients with low serum progesterone levels one day prior to warmed blastocyst transfer in hormone replacement treatment and natural cycles is likely to be intensively explored in near future.


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