A genetic marker of risk in HIV-infected individuals with a history of hazardous drinking

The toxin fluoroacetate occurs naturally in many southwestern Australian species of the legume genera Gastrolobium and Oxylobium. No fluoroacetate-bearing species are known from southeastern Australia. Herbivores have evolved a high level of genetic tolerance to this toxin; this has persisted in some mammalian herbivores whose range now extends beyond the range of the toxic plants. Other species of mammals have acquired tolerance since extending their range into south-western Australia. This tolerance can be used as a genetic marker to identify the geographic origin and trace the subsequent spread of herbivorous mammals in southern Australia. In this paper, this marker has been used to clarify the recent evolutionary history of the western grey kangaroo, the tammar wallaby and the bush rat.

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Multiple genetic marker analysis challenges the introduction history of Ulva australis (Ulvales, Chlorophyta) on French coasts

European Journal of Phycology ◽

10.1080/09670262.2021.1876249 ◽

2021 ◽

pp. 1-13

Author(s):

Pierre-Guy Sauriau ◽

Manon Dartois ◽

Vanessa Becquet ◽

Fabien Aubert ◽

Valérie Huet ◽

...

Keyword(s):

Genetic Marker ◽

Introduction History ◽

Marker Analysis ◽

Ulva Australis ◽

History Of

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Personalized normative feedback for hazardous drinking among college women: Differential outcomes by history of incapacitated rape.

Psychology of Addictive Behaviors ◽

10.1037/adb0000657 ◽

2021 ◽

Author(s):

Anna E. Jaffe ◽

Jessica A. Blayney ◽

Scott Graupensperger ◽

Cynthia A. Stappenbeck ◽

Michele Bedard-Gilligan ◽

...

Keyword(s):

College Women ◽

Hazardous Drinking ◽

Normative Feedback ◽

Personalized Normative Feedback ◽

Differential Outcomes ◽

History Of

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The PECAM-1 gene polymorphism — a genetic marker of myocardial infarction

Open Life Sciences ◽

10.2478/s11535-009-0042-0 ◽

2009 ◽

Vol 4 (4) ◽

pp. 515-520 ◽

Cited By ~ 2

Author(s):

Hrvoje Reschner ◽

Aleksandra Milutinovic ◽

Danijel Petrovič

Keyword(s):

Myocardial Infarction ◽

Gene Polymorphism ◽

Genetic Marker ◽

Serum Levels ◽

Control Group ◽

Genotype Distribution ◽

Cross Sectional ◽

Platelet Endothelial Cell Adhesion ◽

History Of ◽

Sectional Analysis

AbstractWe investigated a possible association between the C373G (Leu125Val) polymorphism in the platelet endothelial cell adhesion molecule-1 (PECAM-1) and myocardial infarction (MI) among patients with type 2 diabetes (T2DM) in the Slovene population (Caucasians). The study population of this cross-sectional analysis consisted of 452 subjects with T2DM lasting more than 10 years: 142 patients with MI (MI group) and 310 patients (control group) with no history of coronary diseases. There were significant differences of PECAM-1 genotype distribution in patients with MI (CC=28.2%, CG=47.2% and GG=24.6%) compared with subjects in the control group (CC=17.1%, CG=53.5% and GG=29.4%). The multivariate model showed that the CC genotype of the PECAM-1 gene polymorphism (C373G) (OR=1.9, 95% CI 1.2–3.0, P=0.007) was an independent risk factor for MI. The C allele frequency was also significantly higher (P=0.005) in MI (51.8%) than in control subjects (41%). In addition, our study revealed the connection between smoking habits, the duration of diabetes and the total and LDL cholesterol serum levels and MI in Slovene T2DM patients. We suggest that the tested polymorphism of PECAM-1 (C373G) is associated with MI. Therefore, it might be used as genetic marker of MI in T2DM.

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