Chemical Composition of Syzygium cumini (L.) Skeels Leaf Essential Oil with Respect to its Uses from North East Region of India

2020 ◽  
Vol 23 (3) ◽  
pp. 601-607
Author(s):  
Neelav Sarma ◽  
Twahira Begum ◽  
Sudin Kumar Pandey ◽  
Roktim Gogoi ◽  
Sunita Munda ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Syzygium Cumini ◽  
North East ◽  
East Region ◽  
Leaf Essential Oil

A comparative analysis of bark and leaf essential oil and their chemical composition, antioxidant, anti-inflammatory, antimicrobial activities and genotoxic potential of North East Indian Cinnamomum zeylanicum Blume

2019 ◽  
Vol 09 ◽  
Author(s):  
Roktim Gogoi ◽  
Neelav Sarma ◽  
Rikraj Loying ◽  
Sudin Kumar Pandey ◽  
Twahira Begum ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Protein Denaturation ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Cinnamomum Zeylanicum ◽  
North East ◽  
Leaf Essential Oil ◽  
Anti Inflammatory

Background: Cinnamomum zeylanicum Blume bark and leaf essential oil possesses eugenol as the major component. Both the essential oil have the potential antioxidant, anti-inflammatory, antimicrobial and negligible genotoxicity. Objective: A comparative chemical composition and biological evaluation of Cinnamomum zeylanicum Blume, bark and leaf essential oils, originated from North-East India has been investigated in the present study. Methods: Gas chromatography/mass spectroscopy analysis was used to investigate the chemical composition of the essential oil samples. DPPH free radical scavenging activity, reducing power assay was used for antioxidant activity evaluation. Similarly, egg albumin denaturation assay, protease inhibitory activities were used for anti-inflammatory activity, while genotoxicity was evaluated by using Allium cepa assay. Results: The results showed that eugenol is the major component of C. zeylanicum bark (84.48%) and leaf (48.78 %) essential oil. Significant antioxidant activity were observed for both essential oils in the DPPH free radical scavenging assay (IC50= 103.2 μg/mL, bark; IC50= 234.7 μg/mL, leaf), and reducing power assay (absorbance of 1.802 nm, 0.907 nm in 48 µg/mL for bark and leaf essential oil respectively). In-vitro anti-inflammatory activity revealed strong potential of leaf essential oil (protein denaturation assay, IC50= 0.05279 μg/mL; protease inhibitory activity IC50= 3.607 μg/mL) in comparison to bark essential oil (protein denaturation assay IC50= 0.1491, protease inhibitory activity IC50= 61.06). Allium cepa root growth test, mitotic index, and chromosomal aberration test were performed to investigate the genotoxicity of C. zeylanicum bark and leaf essential oil, which resulted no toxic nature of both the essential oils. Antimicrobial activity against eight bacterial and fungal strains revealed good antimicrobial properties with the MIC value of Staphylococcus aureus at 5 μL/mL (bark), Aspergillus niger at 2.5 μL/mL (bark); Bacillus cereus at 5 μL/mL (leaf), Aspergillus niger at 2.5 μL/mL (leaf). Conclusion: Collectively, these findings indicated the strong biological potential of both essential oils, although bark essential possesses better biologically activities than the leaf essential oil and could be used in the food and beverages industries.

Chemical Composition of Leaf Essential Oil of Psidium guajava L. from North East India

2019 ◽  
Vol 22 (1) ◽  
pp. 248-253 ◽  
Author(s):  
Angana Borah ◽  
Sudin Kumar Pandey ◽  
Saikat Haldar ◽  
Mohan Lal
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Psidium Guajava ◽  
North East India ◽  
North East ◽  
Leaf Essential Oil

scholarly journals Chemical composition and insecticidal activity of Aeollanthus pubescens Benth leaf essential oil on the malaria vector Anopheles gambiae (Diptera: Culicidae)

2020 ◽  
Author(s):  
Roméo Barnabé Bohounton ◽  
Luc Salako Djogbénou ◽  
Oswald Yédjinnavênan Djihinto ◽  
Oronce Sedjro-Ludolphe Dedome ◽  
Pierre Marie Sovegnon ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Anopheles Gambiae ◽  
Malaria Vector ◽  
Larval Mortality ◽  
Alternative Approach ◽  
Leaf Essential Oil ◽  
Republic Of Benin ◽  
The Republic ◽  
Major Malaria Vector

AbstractThe use of synthetic insecticides is responsible for many cases of resistance in insects. Therefore, the use of natural molecules of ecological interest with insecticidal properties turns out to be an alternative approach to the use of synthetic insecticides. This study aims at investigating the larvicidal, adulticidal activity and the composition of the essential oil of Aeollanthus pubescens Benth on the major malaria vector Anopheles gambiae.The leaves of Aeollanthus pubescens were collected in the South of the Republic of Benin. Three reference strains of Anopheles gambiae s.s. such as Kisumu, Kiskdr and Acerkis were used. The chemical composition of the essential oil was analysed by gas chromatography coupled to mass spectrometry. Larvae were exposed to the essential oil extract for 24 h. Adult mosquitoes were exposed to the fragment nets coated with the essential oil for 3 min. Larval mortality and adult survivorship were monitored.Fourteen components were identified representing 98.31% of the total of oil. The major components were carvacrol (51.06 %), thymyle acetate (14.01 %) and γ-terpinene (10.60 %). The essential oil has remarkable larvicidal properties with LC50 of 29.26, 22.65, and 28.37 ppm respectively on Kisumu, Acerkis and Kiskdr strains. With the fragment net treated at 165 µg/cm2, the KDT50 of both Acerkis (1.71 s, p < 0.001) and Kiskdr (2.67 s, p < 0.001) individuals were significantly lower than that of Kisumu (3.77 s). The lifespan of the three mosquito strains decreased respectively to one day for Kisumu (p < 0.001), two days for Acerkis (p < 0.001) and three days for Kiskdr (p < 0.001) compared to their control.Our findings show that the Aeollanthus pubescens essential oil is an efficient larvicide and adulticide against malaria vector Anopheles gambiae. This bioinsecticidal activity is a promising discovery for the control of the resistant malaria-transmitting vectors.

scholarly journals Chemical Composition of Cinnamomum verum Leaf and Flower Essential Oils and Analysis of Their Antibacterial, Insecticidal, and Larvicidal Properties

Molecules ◽  
2021 ◽  
Vol 26 (20) ◽  
pp. 6303
Author(s):  
Arunaksharan Narayanankutty ◽  
Krishnaprasad Kunnath ◽  
Ahmed Alfarhan ◽  
Rajakrishnan Rajagopal ◽  
Varsha Ramesh
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Callosobruchus Maculatus ◽  
Sitophilus Oryzae ◽  
Microbial Pathogens ◽  
Traditional Medicines ◽  
Significant Toxicity ◽  
Leaf Essential Oil ◽  
Different Parts

Cinnamomum verum is widely used in traditional medicines, and the different parts of the plant, such as bark, leaves, and flowers, are used for essential oil production. The present study compared the chemical composition of the essential oil of C. verum extracted from the leaves and flowers. In addition, efficacy of these essential oils against the two common pests Sitophilus oryzae and Callosobruchus maculatus was also evaluated. The results indicated the presence of cinnamaldehyde, eugenol, caryophyllene, and linalool in these essential oils, however, at different concentrations. The leaf essential oil was found to be 10–20% more effective as a fumigant against both the pests. Likewise, the leaf essential oil found to repel these pests even at lower concentrations than that of flower essential oil of C. verum. Besides, these essential oils were also effective in controlling the growth of various gram positive and gram negative microbial pathogens and possibly a safeguard for human health. On contrary, both the essential oils were found to be safe for the application on grains, as indicated by their germination potentials. It was also observed that these essential oils do not cause any significant toxicity to guppy fishes, thus confirming their ecological safety for use as a biopesticide.

scholarly journals Variation of essential oil composition of Eucalyptus camaldulensis (myrtaceae) from the Montengero coastline

2010 ◽  
pp. 151-158 ◽  
Author(s):  
Slavenko Grbovic ◽  
Dejan Orcic ◽  
Maria Couladis ◽  
Emilija Jovin ◽  
Dusan Bugarin ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Eucalyptus Camaldulensis ◽  
Essential Oil Composition ◽  
Oil Yield ◽  
Oil Composition ◽  
Oxygenated Monoterpenes ◽  
Sesquiterpene Alcohol ◽  
Major Class ◽  
Leaf Essential Oil

In the current study the essential oil obtained from the leaves of Eucalyptus camaldulensis plants collected from five localities of the Montenegro coastline was analyzed. The oil yield varied from 0.63 % (Kotor) up to 1.59% (Tivat). The chemical composition of the leaf essential oil was analyzed using GC-MS technique. Monoterpene hydrocarbons were a major class of compounds. Among them, dominant compounds were p-cymene (17.38-28.60%), ?-phellandrene (12.35-14.47%) and ?-pinene (0.94-11.48%). The second largest group was oxygenated monoterpenes with cryptone (4.97-7.25) and terpinene-4-ol (2.75-4.21%) as predominant. Besides high content of sesquiterpene alcohol spathulenol (7.83-14.15%) was found. According to the results obtained E. camaldulensis from Montenegro can be classified in the chemotype with low 1,8-cineole and high p-cymene and cryptone ratio.

Anti-Proliferative Activity of Piper trioicum Leaf Essential Oil Based on Phytoconstituent Analysis, Molecular Docking and In Silico ADMET Approaches

2021 ◽  
Vol 25 ◽  
Author(s):  
Sudipta Jena ◽  
Asit Ray ◽  
Ambika Sahoo ◽  
Prabhat Kumar Das ◽  
Pradeep Kumar Kamila ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Cell Lines ◽  
In Silico ◽  
Proliferative Activity ◽  
In Silico Admet ◽  
Leaf Essential Oil ◽  
Ht 29

Background: The essential oils isolated from several medicinal plants are reported to have anticancer activities. Both the essential oil and extracts of many Piper species (Piperaceae) possess potential cytotoxic effect against cancer cell lines and are being used in traditional system of medicine for the treatment of cancer. There is a need to evaluate and validate the anticancer properties of essential oils extracted from other wild species of Piper. Objective: The current research was undertaken to determine the chemical composition and investigate the anti-proliferative activity of wild growing Piper trioicum leaf essential oil. The selected five major constituents were subjected to molecular docking to identify possible modes of binding against serine/threonine-protein kinase (MST3) protein Methods: The essential oil of leaf of P. trioicum was extracted by hydro distillation method and its chemical composition was carried out by GC-FID and GC-MS. The anti-proliferative activity of the essential oil was evaluated by MTT assay against normal (3T3-L1) and various cancer (HCT 116, HT-29, PC-3 and HepG2) cell lines. Molecular docking analysis was performed using AutoDock 4.2 software. The pharmacokinetic and pharmacodynamic properties of the major constituents were determined using absorption, distribution, metabolization, excretion and toxicity (ADMET) analysis. Results: The GC-MS analysis revealed the identification of 45 constituents with δ-cadinene (19.57%), germacrene-D (8.54%), β-caryophyllene (6.84%), 1-epi-cubenol (4.83%) and α-pinene (4.52%) were found to be predominant constituents in the leaf essential oil of P. trioicum. The highest cytotoxicity of essential oil was observed against HT-29 cells (IC50 value of 33.14 µg/ml). 1-epi-cubenol and δ-Cadinene exhibited low binding energy values of -6.25 and -5.92 kcal/mol, respectively. For prediction of in silico pharmacokinetic and druglike properties of the major compounds, ADMET prediction tool was also used, the results of which came within the ideal range. Conclusion: The present findings demonstrated that P. trioicum essential oil possesses significant anti-proliferative activity and could be effective against cancer treatment.

Chemical Composition and Antioxidant Activity of the Leaf Essential Oil of Schefflera venulosa

2021 ◽  
Author(s):  
Sudipta Jena ◽  
Asit Ray ◽  
Ambika Sahoo ◽  
Pradeep Kumar Kamila ◽  
Sanghamitra Nayak ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Leaf Essential Oil
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