A computational fluid dynamics study pre- and post-fistula closure in a coronary artery fistula

2019 ◽  
Vol 23 (1) ◽  
pp. 33-42 ◽  
Author(s):  
Haoyao Cao ◽  
Yue Qiu ◽  
Ding Yuan ◽  
Jianqun Yu ◽  
Da Li ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Coronary Artery ◽  
Coronary Artery Fistula ◽  
Fistula Closure

A Giant Right Coronary Artery of Diffuse Ectasia Induced by a Right Ventricular Fistula

2015 ◽  
Vol 18 (6) ◽  
pp. 253
Author(s):  
Renyuan Li ◽  
Yiming Ni ◽  
Peng Teng ◽  
Weidong Li
Keyword(s):  
Coronary Artery ◽  
Right Coronary Artery ◽  
Artery Bypass ◽  
Coronary Artery Fistula ◽  
Rare Entity ◽  
Fistula Closure ◽  
Unique Case ◽  
Coronary Ectasia ◽  
The Right ◽  
Giant Size

<p>Coronary artery fistula (CAF) is a rare entity. Sometimes it may associate with mild diffuse or segmental coronary ectasia. CAF with giant coronary artery is exceptionally rare. We present a unique case of a 49-year-old female patient with a giant right coronary artery of diffuse ectasia coexisting with a fistula draining into the right ventricle. To our best knowledge, CAF with diffuse coronary ectasia of such giant size has never been reported. The patient was treated successfully by resection of the dilated right coronary artery, fistula closure, and coronary artery bypass grafting.</p>

scholarly journals An introduction to computational fluid dynamics based on numerical simulation of pulsatile flow in the left coronary artery

2012 ◽  
Vol 3 ◽  
pp. 366-374
Author(s):  
Jarosław Wasilewski ◽  
Kryspin Mirota ◽  
Sylwia Peryt-Stawiarska ◽  
Andrzej Nowakowski ◽  
Lech Poloński ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Numerical Simulation ◽  
Computational Fluid Dynamics ◽  
Coronary Artery ◽  
Pulsatile Flow ◽  
Left Coronary Artery

Long-Term Follow-Up of Pediatric Patients After Congenital Coronary Artery Fistula Closure

2020 ◽  
Vol 41 (7) ◽  
pp. 1346-1353
Author(s):  
Xiaoyong Li ◽  
Laichun Song ◽  
Ming Xu ◽  
Gangcheng Zhang ◽  
Jing Jin
Keyword(s):  
Coronary Artery ◽  
Pediatric Patients ◽  
Coronary Artery Fistula ◽  
Fistula Closure ◽  
Long Term Follow Up ◽  
Congenital Coronary Artery Fistula

scholarly journals Functional assessment of coronary artery disease by intravascular ultrasound and computational fluid dynamics simulation

2014 ◽  
Vol 33 (10) ◽  
pp. 645.e1-645.e4 ◽  
Author(s):  
Sebastián Carrizo ◽  
Xinzhou Xie ◽  
Rafael Peinado-Peinado ◽  
Angel Sánchez-Recalde ◽  
Santiago Jiménez-Valero ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Coronary Artery Disease ◽  
Computational Fluid Dynamics ◽  
Coronary Artery ◽  
Intravascular Ultrasound ◽  
Functional Assessment ◽  
Dynamics Simulation ◽  
Computational Fluid Dynamics Simulation ◽  
Artery Disease

scholarly journals The relationship between coronary stenosis morphology and fractional flow reserve: a computational fluid dynamics modelling study

2021 ◽  
Author(s):  
Roberto T F Newcombe ◽  
Rebecca C Gosling ◽  
Vignesh Rammohan ◽  
Patricia V Lawford ◽  
D Rodney Hose ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Coronary Artery ◽  
Fractional Flow Reserve ◽  
Computational Modelling ◽  
Fractional Flow ◽  
Cfd Modelling ◽  
Flow Reserve ◽  
The Relationship ◽  
Lesion Severity

Abstract Background International guidelines mandate the use of fractional flow reserve (FFR) and/or non-hyperaemic pressure ratios to assess the physiological significance of moderate coronary artery lesions to guide revascularisation decisions. However, they remain underused such that visual estimation of lesion severity continues to be the predominant decision-making tool. It would be pragmatic to have an improved understanding of the relationship between lesion morphology and haemodynamics. Aims To compute virtual FFR (vFFR) in idealised coronary artery geometries with a variety of stenosis and vessel characteristics Methods Coronary artery geometries were modelled, based upon physiologically realistic branched arteries. Common stenosis characteristics were studied, including % narrowing, length, eccentricity, shape, number, position relative to branch, and distal (myocardial) resistance. Computational fluid dynamics (CFD) modelling was used to calculate vFFRs using the VIRTUheartTM system. Results Percentage lesion severity had the greatest effect upon FFR. Any ≥80% diameter stenosis in two views (i.e. concentric) was physiologically significant (FFR ≤ 0.80), irrespective of length, shape or vessel diameter. Almost all eccentric stenoses and all 50% concentric stenoses were physiologically non-significant, whilst 70% uniform concentric stenoses about 10mm long straddled the ischaemic threshold (FFR 0.80). A low microvascular resistance (MVR) reduced FFR on average by 0.05, and a high MVR increased it by 0.03. Conclusions Using computational modelling, we have produced an analysis of virtual FFR that relates stenosis characteristics to haemodynamic significance. The strongest predictor of a positive virtual FFR was a concentric, ≥80% diameter stenosis. The importance of MVR was quantified. Other lesion characteristics have a limited impact.

Investigation of Wall Shear Stress Over an Early Atherosclerotic Plaque in the Left Coronary Artery of a Patient by Intravascular Ultrasound and Computational Fluid Dynamics

2009 ◽  
Author(s):  
Jin Suo ◽  
Michael McDaniel ◽  
Saurabh Dhawan ◽  
Habib Samady ◽  
Don Giddens
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Coronary Artery ◽  
Intravascular Ultrasound ◽  
Atherosclerotic Plaque ◽  
Left Coronary Artery ◽  
Invasive Coronary Angiography ◽  
Local Flow ◽  
Measured Flow

A small isolated region with mild atherosclerotic thickening in the left anterior descending (LAD) coronary artery was identified in a relatively young patient using invasive coronary angiography. The left main (LM) coronary artery and LAD were reconstructed based on biplanar angiography images and intravascular ultrasound (IVUS). The flow field in the lumen was simulated by computational fluid dynamics (CFD) with Doppler-measured flow boundary conditions. The results offer insight into the local flow environment in the neighborhood of an early atherosclerotic plaque in a specific human subject under in vivo conditions. The investigation is continuing with other patients who have mild plaques in the left coronary artery in an effort to elucidate in vivo atherogenesis.

scholarly journals Integrating Patient-Specific Electrocardiogram Signals and Image-Based Computational Fluid Dynamics Method to Analyze Coronary Blood Flow in Patients during Cardiac Arrhythmias

2019 ◽  
Vol 40 (2) ◽  
pp. 264-272
Author(s):  
Szu-Hsien Chou ◽  
Kuan-Yu Lin ◽  
Zhen-Ye Chen ◽  
Chun-Jung Juan ◽  
Chien-Yi Ho ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Blood Flow ◽  
Coronary Artery ◽  
Cardiac Arrhythmia ◽  
Coronary Arteries ◽  
Flow Rate ◽  
Blood Flow Rate ◽  
Patient Specific ◽  
Ecg Signals

Abstract Purpose The aim of this study was to use the computational fluid dynamics (CFD) method, patient-specific electrocardiogram (ECG) signals, and computed tomography three-dimensional image reconstruction technique to investigate the blood flow in coronary arteries during cardiac arrhythmia. Methods Two patients with premature ventricular contraction-type cardiac arrhythmia and one with atrial fibrillation-type cardiac arrhythmia were investigated. The inlet velocity of the coronary artery in simulation was applied with the measured velocity profile of the left ventricular outflow tract (LVOT) from the Doppler echocardiography. The measured patient central aortic blood pressure waveform was employed for the coronary artery outlet in simulation. The no-slip boundary condition was applied to the arterial wall. Results For the patient with irregular cardiac rhythms (Case I), the coronary blood flow rate under the shortened and lengthened cardiac rhythms were 0.66 and 0.96 mL/s, respectively. In Case II, the maximum velocity at the LVOT under a normal heartbeat was found to be 101 cm/s, whereas the average value was 73 cm/s. In Case III, the patient was also diagnosed with a congenital stenosis problem at the myocardial bridge (MCB) at the LAD. The measured blood flow rate at the MCB of the LAD for the three heartbeats in Case III was found to be 0.68, 1.08, and 1.14 mL/s. Conclusion The integration of patient-specific ECG signals and image-based CFD methods can clearly analyze hemodynamic information for patients during cardiac arrhythmia. The cardiac arrhythmia can reduce the blood flow in the coronary arteries.

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