Cytotoxic flavonoids from the fruits of Derris indica

2017 ◽  
Vol 19 (12) ◽  
pp. 1198-1203 ◽  
Author(s):  
Chalotorn Saraphon ◽  
Kampeebhorn Boonloh ◽  
Veerapol Kukongviriyapan ◽  
Chavi Yenjai
Keyword(s):  
Derris Indica

scholarly journals Methylkarranjic acid and Pongamol from Derris indica Seeds and their Antibacterial Activity

1970 ◽  
Vol 6 (1) ◽  
pp. 9-13 ◽  
Author(s):  
M Abdullahil Baki ◽  
Golam Sadik ◽  
KAM Shahadat Hossain Mondal ◽  
M Ashilk Mosaddik ◽  
M Mukhlesur Rahman
Keyword(s):  
Antibacterial Activity ◽  
Phenolic Compounds ◽  
Soluble Fraction ◽  
Ethanolic Extract ◽  
2D Nmr ◽  
Shigella Dysenteriae ◽  
E Coli ◽  
Nmr Data ◽  
Test Organisms ◽  
Derris Indica

Two phenolic compounds, methylkarranjic (1) acid and pongamol (2), were isolated from the petroleum ether soluble fraction of an ethanolic extract of Derris indica seeds. The structures of these compounds were confirmed by LC-MS and a series of 1D and 2D NMR data. The solvent solvent partionates of the ethanolic extract and compounds (1 and 2) exhibited moderate antibacterial activity against several test organisms. The minimum inhibitory concentrations (MICs) of 1 and 2 were found to be in the range of 32-128 μg/ml against Bacillus megatorium, Streptococcus β-haemolyticus, Shigella dysenteriae and E. coli. Key words: Derris indica; Leguminosae; Methylkarranjic acid; Pongamol; Antibacterial activity Dhaka Univ. J. Pharm. Sci. 6(1): 9-13, 2007 (June) The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

scholarly journals Allelopathy in a Leguminous Mangrove Plant, Derris indica: Protoplast Co-culture Bioassay and Rotenone Effect

2015 ◽  
Vol 10 (5) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Aya Inoue ◽  
Daisuke Mori ◽  
Reiko Minagawa ◽  
Yoshiharu Fujii ◽  
Hamako Sasamoto
Keyword(s):  
Suspension Culture ◽  
Basal Medium ◽  
Culture Method ◽  
Mangrove Plant ◽  
Lettuce Seedling ◽  
Mannitol Solution ◽  
Allelopathic Activity ◽  
Young Leaves ◽  
2,4 Dichlorophenoxyacetic Acid ◽  
Derris Indica

To investigate allelopathic activity of a leguminous mangrove plant, Derris indica, the ‘Protoplasts Co-culture Method’ for bioassay of allelopathy was developed using suspension culture. A suspension culture was induced from immature seed and sub-cultured in Murashige and Skoog's (MS) basal medium containing 10 μM each of 2,4-dichlorophenoxyacetic acid (2,4-D) and 6-benzyladenine (BA). The protoplasts were isolated using the separate wells method with 2% each of Cellulase RS, Driselase 20 and Macerozyme R10 in 0.4 M mannitol solution. Protoplast cultures of D. indica revealed that high concentrations of cytokinins, BA and thidiazuron, were effective for cell divisions. The co-cultures of D. indica protoplasts with recipient lettuce protoplasts using 96 multi-well culture plates were performed in MS basal medium containing 0.4 M mannitol solution and 1 μM 2,4-D and 0.1 μM BA. The protoplast density of D. indica used in co-culturing varied from 6 × 103 - 105 / mL. Very strong inhibitory allelopathic effects of D. indica protoplasts on lettuce protoplast growth were found. A similar strong inhibitory allelopathic activity of dried young leaves on lettuce seedling growth was also observed by using the sandwich method. Rotenone, which is a component of Derris root, dissolved in DMSO, was highly inhibitory on the growth of lettuce protoplasts in culture and this could be one of the causes of the strong allelopathic activity of D. indica.

Inhibitory effects of flavonoids from stem bark of Derris indica on the formation of advanced glycation end products

2014 ◽  
Vol 158 ◽  
pp. 437-441 ◽  
Author(s):  
Pornpat Anusiri ◽  
Siwattra Choodej ◽  
Pranom Chumriang ◽  
Sirichai Adisakwattana ◽  
Khanitha Pudhom
Keyword(s):  
Advanced Glycation End Products ◽  
Stem Bark ◽  
Inhibitory Effects ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products ◽  
Derris Indica

scholarly journals Antifungal Potentials of Derris indica (LAM.) Bennet Extractives

2014 ◽  
Vol 7 ◽  
pp. 61-65
Author(s):  
Omar Ali Mondal ◽  
KAMSH Mondal ◽  
Nurul Islam
Keyword(s):  
Activity Index ◽  
Pathogenic Fungi ◽  
Stem Bark ◽  
Bark Extract ◽  
Root Bark ◽  
Stem Wood ◽  
Wood Extracts ◽  
Wood Extract ◽  
Derris Indica ◽  
Activity Indices

Antifungal activity of the D. indica (Lam.) Bennet. extractives collected in CHCl3 and methanol were tested against seven pathogenic fungi F. vasinfectum, A. fumigatus, A. niger, A. flavus, Mucor sp., C. albicans and P. notatum at concentrations of 50 and 200 ?g/disc along with a standard Nystatin (50 ?g/disc). The fruit shell extract showed activity index against C. albicans and P. notatum. The leaf and the root bark extracts were responsive on A. fumigatus, C. albicans, P. notatum and F. vasinfectum. For the root wood extract F. vasinfectum, A. fumigatus,, C. albicans were responsive. For the seed, stem bark and stem wood extract showed activity index against A. flavus, C. albicans, A. fumigatus P. notatum and Mucor sp. According to the intensity of activity indices D. indica extracts (CHCl3) could be arranged in a descending order of fruit shell > leaf > root bark > root wood > seed >stem wood> stem bark extract. For the MeOH extracts the fruit shell, leaf, root bark and root wood extracts showed activity indices against A. fumigatus, C. albicans , P. notatum , Mucor sp., F vasinfectum, and A. flavus. In case of the seed, stem bark and stem wood extracts A. flavus, C. albicans, A. fumigatus, P. notatum and Mucor sp. were responsive. According to the intensity of activity indices D. indica extracts (MeOH) could be arranged in a descending order of fruit shell > leaf > root bark > root wood >seed> stem bark > stem wood extract. DOI: http://dx.doi.org/10.3329/jles.v7i0.20122 J. Life Earth Sci., Vol. 7: 61-65, 2012

scholarly journals Newer Constituents of Derris Indica Stem

2008 ◽  
Vol 3 (8) ◽  
pp. 1934578X0800300 ◽  
Author(s):  
Thangaraj Shankar ◽  
Shanmugam Muthusubramanian ◽  
Rathinasamy Gandhidasan
Keyword(s):  
Spectral Studies ◽  
New Compounds ◽  
Derris Indica

Two new compounds, 5,7-dihydroxy-6-methyl-4′-methoxyisoflavone (6-methylbiochanin A) (1) and cis-3,5-diphenylpiperidine-2,6-dione (2) were isolated from the young stems of Derris indica along with desmethoxykanugin (3), 3′, 5′-dimethoxy-(2″, 3″: 7, 8)furanoflavone (4) and 7,4′-dimethyldaidzein (5). The structures of these compounds were determined by means of chemical and spectral studies.

Chromatographic Analysis for Fatty Acids and Lipid-Soluble Bioactives of Derris indica Crude Seed Oil

2009 ◽  
Vol 70 (1-2) ◽  
pp. 103-108 ◽  
Author(s):  
Mohamed Fawzy Ramadan ◽  
Khaled Mohamed Mohamed Wahdan ◽  
Hefnawy T. M. Hefnawy ◽  
S. G. Kinni ◽  
L. N. Rajanna ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Chromatographic Analysis ◽  
Seed Oil ◽  
Derris Indica

4-Methoxy-7-phenyl-6,7-dihydrofuro[3,2-g]chromen-5-one

2006 ◽  
Vol 62 (5) ◽  
pp. o1984-o1986
Author(s):  
Suchada Chantrapromma ◽  
Hoong-Kun Fun ◽  
Sorwaporn Koysomboon ◽  
Kan Chantrapromma
Keyword(s):  
Title Compound ◽  
Phenyl Ring ◽  
Methoxy Group ◽  
Π Interactions ◽  
Compound C ◽  
Derris Indica

The title compound, C18H12O4, known as pinnatin, is a furanoflavone isolated from Derris indica (Lam.). The furanoflavone nucleus is almost planar. The phenyl ring is axially attached to the furanoflavone skeleton. The methoxy group deviates slightly from the plane of the molecule. The molecules are linked in a zigzag manner through C—H...O interactions into molecular ribbons along the b axis. Further stabilization is provided by weak C—H...π and π–π interactions.

scholarly journals A NEW ALKALOID FROM DERRIS INDICA (LAM) BENNETT SEED OIL: ISOLATION AND CHARACTERIZATION

2021 ◽  
pp. 56-59
Author(s):  
NUZHAT TABASSUM ◽  
VIDYASAGAR G. M.
Keyword(s):  
Column Chromatography ◽  
Seed Oil ◽  
Herbal Medicines ◽  
Antimicrobial Properties ◽  
Crystalline Fraction ◽  
Traditional Medicines ◽  
Traditional Health ◽  
Isolation And Characterization ◽  
Traditional Health Care ◽  
Derris Indica

Objective: The aim of the study was to isolate alkaloid compound from seed oil of Derris indica (Lam) Bennett where relevant antimicrobial properties in traditional medicines. Methods: The plant was selected based on their usage in traditional medicines and ethnopharmacological importance. Crude extract from D. indica seeds fractioned with different solvents through column chromatography. Isolated pure fraction was identified and characterized using UV, FTIR, 1HNMR and Mass spectroscopy. Results: D. indica seeds hexane extract on fractionation with ethyl acetate and methanol through column chromatography yielded a crystalline fraction. The fraction was identified as alkaloid group and characterized as a 2-(6-methoxyphenanthridin-8-yl) propan-2-ol. The compound is a new report from D. indica seed oil. Conclusion: The usage of D. indica plant is much in traditional health care for treatment of diseases. Isolation of alkaloid compound from D. indica seeds in traditional herbal medicines may be found a good source of drug discovery.

scholarly journals Acetylcholinesterase inhibition and cytotoxicity of flavonoids and chalcones from Derris indica

ScienceAsia ◽  
2016 ◽  
Vol 42 (4) ◽  
pp. 247 ◽  
Author(s):  
Thurdpong Sribuhom ◽  
Chalotorn Saraphon ◽  
Phatharapoll Decharchoochart ◽  
Chantana Boonyarat ◽  
Chavi Yenjai
Keyword(s):  
Acetylcholinesterase Inhibition ◽  
Derris Indica
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