activity indices
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BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e056413
Author(s):  
Violeta Razanskaite ◽  
Constantinos Kallis ◽  
Bridget Young ◽  
Paula R Williamson ◽  
Keith Bodger

ObjectivesKnowledge of the extent of variation in outcome assessment for inflammatory bowel disease (IBD) in routine practice is limited. We aimed to describe and quantify variation in outcome coverage and to explore patient, clinician and practitioner factors associated with it.DesignProspective exploratory mixed-methods study.SettingIBD clinics at six hospitals in North West England with differing electronic health record (EHR) systems.MethodsMixed-methods study comprising: (a) structured observations of outcomes elicited during consultations (102 patients consulting 24 clinicians); (b) retrospective analysis of outcomes recorded in the EHR (909 consultations; 127 clinicians) and (c) semistructured interviews with the 24 observed clinicians. We determined whether specific outcome ‘sets’ were elicited or recorded, including: (1) a minimum set of symptom pairs (‘PRO-2’); (2) symptom sets from disease activity indices and (3) a reference list of 37 symptoms, signs and impacts. Factors associated with variation were explored in univariate and multivariate binary logistic regression analyses and from clinician interviews.ResultsPRO-2 coverage was not invariable (elicited during 81% of observed consultations; recorded in 56% of EHR) and infrequent for complete activity indices (all domains from Harvey-Bradshaw Index: elicited, 18%; recorded, 5%). The median number of outcomes from the reference list elicited per consultation was 12 (13-fold variation) and recorded in EHR was 7 (>20-fold variation). Symptom quantification (PRO-2) seldom adhered closely to standardised descriptors and an explicit timeframe was defined rarely. PRO-2 recording in EHR was associated with a diagnosis of ulcerative colitis (OR: 2.09 (95% CI 1.15 to 3.80)) and nurse-led consultations (OR: 6.98 (95% CI 3.28 to 14.83)) and a three-way model suggested 26% of total variability lay between clinicians, 17% between patients but the remainder was unexplained. Most clinicians expressed preference for individualised health status evaluations versus standardised outcome assessments.ConclusionsThere was little evidence for standardised assessment and recording of IBD outcomes and substantial intra-clinician and inter-clinician variation from one consultation to another. Nurses demonstrated a greater tendency to standardised practice.


Author(s):  
Christopher Ma ◽  
John K. MacDonald ◽  
Tran M. Nguyen ◽  
Joshua Chang ◽  
Niels Vande Casteele ◽  
...  

2021 ◽  
Vol 61 (6) ◽  
pp. 830-835
Author(s):  
M. G. Deminov ◽  
G. F. Deminova ◽  
V. Kh. Depuev ◽  
A. Kh. Depueva

Author(s):  
Sergey N. Filimonov ◽  
Raisa V. Gordeeva ◽  
Olga V. Kuzmenko ◽  
Elena A. Martynova ◽  
Svetlana V. Erdeeva ◽  
...  

The results of the use of electrostatic massage in the miners with vibration disease and with shoulder joint diseases are presented. In the all patients the rehabilitation program included electrostatic massage on the ELGOS device using a lead-out electrode according to the local-segmental method. Patients of the comparison group underwent manual massage of similar areas. Before and after the treatment, the clinical manifestations of vibration disease were evaluated by vibration sensitivity test using a Rydel-Seiffer vibrotone C 64 Hz / C 128 Hz. The dynamics of functional activity indices in the patients with shoulder joint diseases was assessed using a visual analog scale questionnaire. The work showed that the electrostatic massage contributes to a faster restoration of vibration sensitivity, the volume of movements in large joints and a reduction in the clinical manifestations of vibration disease (pain in the fingers, paresthesia, numbness, etc.), which has an advantage in the conditions of the COVID-19 pandemic, since the direct impact of the masseur’s hands on the patient’s body is excluded.


2021 ◽  
Vol 17 ◽  
Author(s):  
Laura Groseanu ◽  
Sorana Petrescu ◽  
Andra Balanescu ◽  
Violeta Bojinca ◽  
Daniela Opris-Belinski ◽  
...  

Background: No fully validated index is available for assessing overall disease activity in systemic sclerosis (SSc). Objectives: To estimate the effect of disease activity as measured by different disease activity indices on the risk of subsequent organ damage. Methods: The European Systemic sclerosis study group activity index (EScSG AI), the European Scleroderma Trials and Research Group Activity Index (r-EUSTAR AI), 12 point activity index proposed by Minier (12point AI) were calculated for 91 patients; the CRISS (The Composite Response Index for Systemic Sclerosis) for patients included after 2016. Data were analysed by parametric and non-parametric tests and logistic regression. Results: EscSG AI, r-EUSTAR AI and 12point AI correlated with lung involvement. EScSG AI and r-EUSTAR AI correlated with diffuse skin involvement. EscSG AI correlated with digital ulcers and diffuse cutaneous involvement and r-EUSTAR AI with renal crisis. Bivariate analysis showed an inverse correlation between the three disease activity scores and forced vital capacity (FVC) (p<0.001) and diffusing capacity for carbon monoxide (DLCO) (p<0.001) and positive correlation with pulmonary fibrosis (p<0.001), modified Rodnan skin score (mRSS) (p<0.001), health assessment questionnaire (HAQ) (p<0.001), systolic pulmonary pressure (sPAP) (p<0.001), C-reactive protein (CRP) (p<0.001) and capillaroscopy scoring (p<0.001) at both baseline visit and at the 3-year follow-up visit. Logistic regression revealed that baseline EScSG AI adjusted for gender and age and that baseline 12-point AI both adjusted and unadjusted predicted worse skin involvement at 3-year follow-up; while adjusted EScSG AI predicted decreasing of DLCO. Also, 12-point AI predicted decline of FVC and higher HAQ scores at 3-year follow up; while baseline r-EUSTAR AI was able to predict muscular deterioration, decline of FVC and the increase of HAQ score during 3 years of following. An active disease according to EScSG AI at first visit predicted progression of joint involvement while an active disease at baseline showed by r-EUSTAR AI predicted muscular deterioration, FVC and DLCO worsening, as well as an increasing in HAQ score during the follow-up period. r-EUSTAR AI was the only score to predict the decrease of FVC in a multiple regression prediction model [OR= 1.306 (1.025, 1.665), p=0.31] while baseline EScSG AI best predicted worsening of DLCO [OR=1.749 (1.104, 2.772), p=0.017]. Conclusion: Our study could not establish a gold standard to assess disease activity in SSc; especially EscSG AI and r-EUSTAR AI could quantify and predict major organ involvement in daily practice. CRISS can be useful as an outcome measure for patients with short disease duration included in clinical studies.


2021 ◽  
Author(s):  
Volker Runkel ◽  
Guido Gerding ◽  
Ulrich Marckmann

An accessible and comprehensive guide to all things acoustic bat detection. This highly illustrated handbook provides an in-depth understanding of acoustic detection principles, study planning, data handling, properties of bat calls, manual identification of species, automatic species recognition, analysis of results, quality assurance and the background physics of sound. No other method of detecting bats is so popular and widespread in the context of environmental assessment and voluntary work as acoustic detection, and its increased use has driven the development of a large number of sophisticated devices and analytical methods. Acoustic detection has become a standard approach for establishing the presence of bats, carrying out species identification and monitoring levels of activity. The resolution, accuracy and scale with which these tasks can be done has risen dramatically with the availability of automated real-time recording. But anyone interested in acoustic recording will quickly recognise that there are still quite a few open questions about the limits and possibilities of acoustic detection. Clear definitions of how to handle the data are usually missing, for example, and there are no clearly described activity indices. In response to the lack of thorough information on the underlying science of acoustic detection, the authors present this handbook.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Rafael Alexandre de Oliveira Deucher ◽  
Arthur de Sá Ferreira ◽  
Leila Paula Alves da Silva Nascimento ◽  
Mariana Soares da Cal ◽  
Jannis Vasileios Papathanasiou ◽  
...  

Background: The integrity of the autonomic nervous system (ANS) is essential for keeping physiological processes stable, even under stress. Since there is growing interest in heart rate variability (HRV) analysis for the noninvasive assessment of the ANS in sickle cell anemia (SCA) patients, we studied the behavior of the ANS in the presence of a stressor that simulates daily-life multitasking, the Glittre ADL test (GA-T). Objectives: To evaluate the involvement of the ANS using HRV in adults with SCA during the GA-T and to quantify the strength of the correlation of HRV with lung and muscle functions. Methods: In this cross-sectional study, 16 adults with SCA and 12 healthy controls without sickle cell disease underwent HRV assessment during the GA-T, pulmonary function tests (spirometry, diffusing capacity for carbon monoxide (DLCO), and respiratory muscle testing). Peripheral muscle function [handgrip strength (HGS) and quadriceps strength (QS)] were also measured. Results: Compared to the healthy controls, adults with SCA showed lower HRV, with worse parasympathetic modulation due to reductions in the following indices: the root-mean-square difference of successive normal iRRs (iRR) (RMSSD); the percentage of pairs of consecutive iRRs whose difference is > 50 m (pNN50); the high-frequency component of heart rate variability (HF); and the standard deviation of instantaneous beat-to-beat variability (SD1) (P < 0.001 for all). Compared to healthy controls, individuals with SCA showed greater sympathovagal imbalance (higher ratio between low-frequency and HF components) and lower complexity of the ANS (lower approximate entropy). The GA-T time was correlated with parasympathetic activity indices: RMSSD (rs = -0.650, P < 0.01); pNN50 (rs = -0.932, P < 0.0001), HF (rs = -0.579, P < 0.01), and SD1 (rs = -0.814, P < 0.0001). Correlations between parasympathetic activity indices and DLCO, HGS, and QS measures were also significant. Conclusions: Adults with SCA have low HRV, with low parasympathetic activity, sympathovagal imbalance, and abnormal ANS complexity. In addition, lower HRV is associated with longer GA-T time, greater impairment of pulmonary diffusion, and greater muscle strength dysfunction.


Author(s):  
Sizheng Steven Zhao ◽  
Elena Nikiphorou ◽  
Adam Young ◽  
Patrick D. W. Kiely

AbstractThis study aimed to examine the progression of large joint involvement from early to established RA in terms of range of movement (ROM) and time to joint surgery, according to the presence of rheumatoid factor (RF). We used a historical longitudinal cohort of early RA patients. Patients were deemed RF negative if all repeated assessments were negative. The rate of progression from normal to any loss of range of movement (ROM) from years 3 to 14 were modelled using generalized estimating equations, for elbows, wrists, hips, knees and ankle, adjusting for confounders. Time to joint surgery was analysed using multivariable Cox models. A total of 1458 patients were included (66% female, mean age 55 years) and 74% were RF-positive. The prevalence of any loss of ROM, from year 3 through to 14 was highest in the wrist followed by ankle, knee, elbow and hip. Odds of loss of ROM increased over time in all joint regions assessed, at around 7–13% per year from year 3 to 14. Time to surgery was similar according to RF-status for the wrist and ankle, but RF-positive cases had a lower hazard of surgery at the elbow (HR 0.37, 0.15–0.90), hip (HR 0.69, 0.48–0.99) and after 10 years at the knee (HR 0.41, 0.25–0.68). Large joints become progressively involved in RA, most frequently affecting the wrist followed by ankle, which is overlooked in composite disease activity indices. RF-negative and positive cases progressed similarly. Treat-to-target approaches should be followed irrespective of RF status.


2021 ◽  
Vol 82 (1) ◽  
pp. 49-51
Author(s):  
A. M. Zainutdinov

The characteristic of structural subdivisions of Нашу Mondor hospital in France, the organization of its surgical service, activity indices of the hospital are given. The peculiarities of work of physicians- interns, teaching of students are described, the merits in organization of medical service to patients, the quality of diagnosis and treatment are noted.


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