Outcome of patients less than 55 years of age with high-risk acute leukemia who did not have an human leukocyte antigen-identical related donor: a long-term study of 97 consecutive patients

2005 ◽  
Vol 46 (6) ◽  
pp. 841-849 ◽  
Author(s):  
Jérôme Cornillon ◽  
Abir Fawaz ◽  
Stéphane Depil ◽  
Françoise Dufosse ◽  
Alain Duhamel ◽  
...  
Keyword(s):  
High Risk ◽  
Acute Leukemia ◽  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Term Study ◽  
Leukocyte Antigen ◽  
Long Term Study ◽  
Related Donor

Outcome of patients less than 55 years of age with high-risk acute leukemia who did not have an HLA-identical related donor: A long-term study of 97 consecutive patients

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 6636-6636
Author(s):  
I. Yakoub-Agha ◽  
J. Cornillon ◽  
S. Depil ◽  
F. Bauters ◽  
J. P. Jouet ◽  
...  
Keyword(s):  
High Risk ◽  
Acute Leukemia ◽  
Term Study ◽  
Long Term Study ◽  
Related Donor

Outcome of patients less than 55 years of age with high-risk acute leukemia who did not have an HLA-identical related donor: A long-term study of 97 consecutive patients

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 6636-6636
Author(s):  
I. Yakoub-Agha ◽  
J. Cornillon ◽  
S. Depil ◽  
F. Bauters ◽  
J. P. Jouet ◽  
...  
Keyword(s):  
High Risk ◽  
Acute Leukemia ◽  
Term Study ◽  
Long Term Study ◽  
Related Donor

A survey of fully haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: a risk factor analysis of outcomes for patients in remission at transplantation

Blood ◽  
2008 ◽  
Vol 112 (9) ◽  
pp. 3574-3581 ◽  
Author(s):  
Fabio Ciceri ◽  
Myriam Labopin ◽  
Franco Aversa ◽  
Jakob M. Rowe ◽  
Donald Bunjes ◽  
...  
Keyword(s):  
Stem Cell ◽  
High Risk ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Acute Leukemia ◽  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Hematopoietic Stem ◽  
Leukocyte Antigen ◽  
Matched Donor

Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) is an alternative treatment to patients with high-risk acute leukemia lacking a human leukocyte antigen-matched donor. We analyzed 173 adults with acute myeloid leukemia (AML) and 93 with acute lymphoblastic leukemia (ALL) who received a haplo-HSCT in Europe. All grafts were T cell–depleted peripheral blood progenitor cells from a direct family or other related donor. At transplantation, there were 25 patients with AML in CR1 (complete remission 1), 61 in more than or equal to CR2, and 87 in nonremission, and 24 with ALL in CR1, 37 in more than or equal to CR2, and 32 in nonremission. Median follow-up was 47 months in AML and 29 months in the ALL groups. Engraftment was observed in 91% of the patients. Leukemia-free survival at 2 years was 48% plus or minus 10%, 21% plus or minus 5%, and 1% for patients with AML undergoing transplantation in CR1, more than or equal to CR2, and nonremission, and 13% plus or minus 7%, 30% plus or minus 8%, and 7% plus or minus 5% in ALL patients, respectively. In conclusion, haplo-HSCT can be an alternative option for the treatment of high-risk acute leukemia patients in remission, lacking a human leukocyte antigen-matched donor.

scholarly journals Related Donor Human Leukocyte Antigen Typing: Developing a Process for Utilization of Buccal Swabs Versus Blood Tubes

2016 ◽  
Vol 22 (3) ◽  
pp. S457-S458
Author(s):  
Kim Schmit-Pokorny ◽  
Cathy Gebhart ◽  
Sophia Hauxwell ◽  
Jeanine Schademann ◽  
JoAnn Tate
Keyword(s):  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Human Leukocyte Antigen Typing ◽  
Leukocyte Antigen ◽  
Buccal Swabs ◽  
Related Donor

scholarly journals Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies

2021 ◽  
Vol Volume 14 ◽  
pp. 2697-2712
Author(s):  
Safak Gül-Klein ◽  
Henriette Hegermann ◽  
Robert Röhle ◽  
Moritz Schmelzle ◽  
Frank Tacke ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Specific Antibodies ◽  
Leukocyte Antigen ◽  
Protocol Biopsies ◽  
Donor Specific Antibodies

scholarly journals Pretransplant human leukocyte antigen antibodies detected by single-antigen bead assay are a risk factor for long-term kidney graft loss even in the absence of donor-specific antibodies

2016 ◽  
Vol 29 (9) ◽  
pp. 988-998 ◽  
Author(s):  
Rudolf Richter ◽  
Caner Süsal ◽  
Stefanie Köhler ◽  
Sara Qidan ◽  
Alicia Schödel ◽  
...  
Keyword(s):  
Risk Factor ◽  
Human Leukocyte Antigen ◽  
Graft Loss ◽  
Human Leukocyte ◽  
Kidney Graft ◽  
Specific Antibodies ◽  
Leukocyte Antigen ◽  
Single Antigen ◽  
Donor Specific Antibodies

Transplantation of the highly human leukocyte antigen–sensitized patient: long-term outcomes and future directions

2006 ◽  
Vol 20 (3) ◽  
pp. 146-156 ◽  
Author(s):  
Alice Peng ◽  
Ashley Vo ◽  
Stanley C. Jordan
Keyword(s):  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Long Term Outcomes ◽  
Future Directions ◽  
Leukocyte Antigen
Sign in / Sign up

Export Citation Format

Share Document