TheOxford Handbook of Treatment Processes and Outcomes in Psychologypresents a multidisciplinary approach to a biopsychosocial, translational model of psychological treatment across the life span. It describes cutting edge research across developmental, clinical, counseling, and school psychology; social work; neuroscience; and psychopharmacology. TheHandbookemphasizes the development of individual differences in resilience and mental health concerns, including social, environmental, and epigenetic influences across the life span, particularly during childhood. TheHandbookis a primer for practitioners and researchers, and is a guide for clinics and oversight bodies responsible for decision making regarding training of staff and the evaluation of treatment effectiveness. TheHandbookis appropriate reading for students in graduate programs in psychology, social work, and counseling. ThisHandbookpresents work by experts from multiple disciplines to readers who otherwise might have difficulty gaining direct access to the works by these authors. Detailed discussions are offered that expand on areas of research and practice that already have a substantive research base, such as self-regulation, resilience, defining evidence-based treatment, and describing client-related variables that influence treatment processes. TheHandbookalso includes chapters devoted to newer areas of research (e.g., neuroimaging, medications as adjuncts to psychological treatment, and the placebo effect). Additionally, it includes chapters that address treatment outcomes, such as evaluating therapist effectiveness, examining treatment outcomes from different perspectives, and assessing the length of treatment necessary to achieve clinical improvement. TheHandbookprovides entrée into research as well as “hands on” guidance and suggestions for practice and oversight, making it a valuable resource for graduate students, seasoned practitioners, researchers, and agencies alike.