Theoretical and Practical Application of Traditional and Accelerated Titration Phase I Clinical Trial Designs: The Wayne State University Experience

Journal of Biopharmaceutical Statistics ◽

10.1080/10543400902800460 ◽

2009 ◽

Vol 19 (3) ◽

pp. 414-423 ◽

Author(s):

Elisabeth I. Heath ◽

Patricia M. LoRusso ◽

S. Percy Ivy ◽

Larry Rubinstein ◽

Michaele C. Christian ◽

...

Keyword(s):

Clinical Trial ◽

Phase I ◽

Phase I Clinical Trial ◽

State University ◽

Practical Application ◽

Wayne State University ◽

Titration Phase ◽

Clinical Trial Designs ◽

University Experience

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Adaptive Bayesian phase I clinical trial designs for estimating the maximum tolerated doses for two drugs while fully utilizing all toxicity information

Biometrical Journal ◽

10.1002/bimj.202000142 ◽

2021 ◽

Author(s):

Yuzi Zhang ◽

Michael Kutner ◽

Zhengjia Chen

Keyword(s):

Clinical Trial ◽

Phase I ◽

Phase I Clinical Trial ◽

Clinical Trial Designs

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Another look at two phase I clinical trial designs

Statistics in Medicine ◽

10.1002/(sici)1097-0258(19991030)18:20<2683::aid-sim193>3.0.co;2-z ◽

1999 ◽

Vol 18 (20) ◽

pp. 2683-2690 ◽

Author(s):

John O'Quigley

Keyword(s):

Clinical Trial ◽

Phase I ◽

Phase I Clinical Trial ◽

Two Phase ◽

Clinical Trial Designs

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An evaluation of phase I clinical trial designs in the continuous dose-response setting

Statistics in Medicine ◽

10.1002/sim.903 ◽

2001 ◽

Vol 20 (16) ◽

pp. 2399-2408 ◽

Author(s):

Barry E. Storer

Keyword(s):

Clinical Trial ◽

Phase I ◽

Dose Response ◽

Phase I Clinical Trial ◽

Continuous Dose ◽

Clinical Trial Designs

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Phase I Clinical Trial of a Genetically Modified and Oncolytic Vaccinia Virus GL-ONC1 in patients with peritoneal carcinomatosis

Zeitschrift für Gastroenterologie ◽

10.1055/s-0032-1324086 ◽

2012 ◽

Vol 50 (08) ◽

Author(s):

UM Lauer ◽

M Zimmermann ◽

U Koppenhöfer ◽

M Bitzer ◽

NP Malek ◽

...

Keyword(s):

Clinical Trial ◽

Phase I ◽

Vaccinia Virus ◽

Peritoneal Carcinomatosis ◽

Genetically Modified ◽

Phase I Clinical Trial

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SAFETY OF A NEW CUBAN PNEUMOCOCCAL CONJUGATE VACCINE: A PHASE I CLINICAL TRIAL IN INFANTS 7 MONTH-OLD

10.26226/morressier.5731f0d7d462b8029237fd99 ◽

2016 ◽

Author(s):

Rinaldo Puga-Gomez

Keyword(s):

Clinical Trial ◽

Phase I ◽

Conjugate Vaccine ◽

Pneumococcal Conjugate Vaccine ◽

Phase I Clinical Trial

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Faculty Opinions recommendation of Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1118816.793494158 ◽

2014 ◽

Author(s):

Thomas Flaig

Keyword(s):

Prostate Cancer ◽

Clinical Trial ◽

Phase I ◽

Abiraterone Acetate ◽

Selective Inhibitor ◽

Phase I Clinical Trial ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant

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Faculty Opinions recommendation of A phase I clinical trial of Ad5/3-Δ24, a novel serotype-chimeric, infectivity-enhanced, conditionally-replicative adenovirus (CRAd), in patients with recurrent ovarian cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718026292.793481389 ◽

2013 ◽

Author(s):

Steve Plaxe ◽

Kristy Ward

Keyword(s):

Ovarian Cancer ◽

Clinical Trial ◽

Phase I ◽

Recurrent Ovarian Cancer ◽

Phase I Clinical Trial ◽

Conditionally Replicative Adenovirus

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Faculty Opinions recommendation of GTL001, A Therapeutic Vaccine for Women Infected with Human Papillomavirus 16 or 18 and Normal Cervical Cytology: Results of a Phase I Clinical Trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726394953.793529283 ◽

2017 ◽

Author(s):

Lucy Dorrell

Keyword(s):

Clinical Trial ◽

Human Papillomavirus ◽

Phase I ◽

Therapeutic Vaccine ◽

Phase I Clinical Trial ◽

Cervical Cytology ◽

Human Papillomavirus 16 ◽

Normal Cervical Cytology

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Faculty Opinions recommendation of Randomized phase I clinical trial of anti-α-synuclein antibody BIIB054.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.736011651.793576740 ◽

2020 ◽

Author(s):

Roger Barker

Keyword(s):

Clinical Trial ◽

Phase I ◽

Phase I Clinical Trial

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Local delivery of CAR T cells targeting fibroblast activation protein is safe in patients with pleural mesothelioma: first report of FAPME, a phase I clinical trial

Annals of Oncology ◽

10.1016/j.annonc.2020.10.474 ◽

2021 ◽

Vol 32 (1) ◽

pp. 120-121

Author(s):

S. Hiltbrunner ◽

C. Britschgi ◽

P. Schuberth ◽

L. Bankel ◽

T.D.L. Nguyen-Kim ◽

...

Keyword(s):

Clinical Trial ◽

T Cells ◽

Phase I ◽

Local Delivery ◽

Fibroblast Activation Protein ◽

Phase I Clinical Trial ◽

Pleural Mesothelioma ◽

First Report ◽

Car T Cells ◽

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