scholarly journals In silico identification and experimental validation of cellular uptake by a new cell penetrating peptide P1 derived from MARCKS

Drug Delivery ◽  
2021 ◽  
Vol 28 (1) ◽  
pp. 1637-1648
Author(s):  
Linlin Chen ◽  
Xiangli Guo ◽  
Lidan Wang ◽  
Jingping Geng ◽  
Jiao Wu ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
In Silico ◽  
Experimental Validation ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
In Silico Identification

scholarly journals In silico identification and experimental validation of hits active against KPC-2 β-lactamase

PLoS ONE ◽  
2018 ◽  
Vol 13 (11) ◽  
pp. e0203241 ◽  
Author(s):  
Raphael Klein ◽  
Pasquale Linciano ◽  
Giuseppe Celenza ◽  
Pierangelo Bellio ◽  
Sofia Papaioannou ◽  
...  
Keyword(s):  
In Silico ◽  
Experimental Validation ◽  
In Silico Identification

scholarly journals A comparison of acyl-moieties for noncovalent functionalization of PLGA and PEG-PLGA nanoparticles with a cell-penetrating peptide

RSC Advances ◽  
2021 ◽  
Vol 11 (57) ◽  
pp. 36116-36124
Author(s):  
Omar Paulino da Silva Filho ◽  
Muhanad Ali ◽  
Rike Nabbefeld ◽  
Daniel Primavessy ◽  
Petra H. Bovee-Geurts ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Plga Nanoparticles ◽  
Cell Penetrating Peptides ◽  
Cell Penetrating Peptide ◽  
Noncovalent Functionalization ◽  
Cell Penetrating ◽  
A Cell

Noncovalent functionalization with acylated cell-penetrating peptides achieves an efficient cellular uptake of PLGA and PEG-PLGA nanoparticles.

Lipid–Cell-Penetrating-Peptide Conjugates as Effective Delivery Systems

Synlett ◽  
2017 ◽  
Vol 28 (15) ◽  
pp. 1897-1900
Author(s):  
Zi-Gang Li ◽  
Yan-Hong Jiang ◽  
Hui Zhao ◽  
Yuan Tian
Keyword(s):  
Cellular Uptake ◽  
Biological Research ◽  
Cell Penetrating Peptide ◽  
Peptide Conjugates ◽  
Cellular Toxicity ◽  
Wide Range ◽  
Cell Penetrating ◽  
Effective Delivery ◽  
Cellular Permeability ◽  
Small Molecule Therapeutics

A lipid–cell-penetrating-peptide (CPP) conjugate was designed to deliver cargoes with poor cellular permeability, including peptides or small-molecule therapeutics, into cells. The lipid–CPP conjugate facilitated the cellular uptake of cargoes noncovalently through an ATP-dependent micropinocytosis mechanism. This delivery system is simple, efficient, has minimal cellular toxicity, and might be useful in a wide range of biological research.

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