Disruption of Transitions in High-Risk Substance Use from Adolescence to Young Adulthood: School, Employment, and Romantic Relationship Factors

2020 ◽  
Vol 55 (7) ◽  
pp. 1129-1137
Author(s):  
Gabriel J. Merrin ◽  
Megan E. Ames ◽  
Clea Sturgess ◽  
Bonnie J. Leadbeater
2008 ◽  
Vol 20 (1) ◽  
pp. 291-318 ◽  
Author(s):  
Eun Young Mun ◽  
Michael Windle ◽  
Lisa M. Schainker

AbstractData from a community-based sample of 1,126 10th- and 11th-grade adolescents were analyzed using a model-based cluster analysis approach to empirically identify heterogeneous adolescent subpopulations from the person-oriented and pattern-oriented perspectives. The model-based cluster analysis is a new clustering procedure to investigate population heterogeneity utilizing finite mixture multivariate normal densities and accordingly to classify subpopulations using more rigorous statistical procedures for the comparison of alternative models. Four cluster groups were identified and labeled multiproblem high-risk, smoking high-risk, normative, and low-risk groups. The multiproblem high risk exhibited a constellation of high levels of problem behaviors, including delinquent and sexual behaviors, multiple illicit substance use, and depressive symptoms at age 16. They had risky temperamental attributes and lower academic functioning and educational expectations at age 15.5 and, subsequently, at age 24 completed fewer years of education, and reported lower levels of physical health and higher levels of continued involvement in substance use and abuse. The smoking high-risk group was also found to be at risk for poorer functioning in young adulthood, compared to the low-risk group. The normative and the low risk groups were, by and large, similar in their adolescent and young adult functioning. The continuity and comorbidity path from middle adolescence to young adulthood may be aided and abetted by chronic as well as episodic substance use by adolescents.


2001 ◽  
Vol 33 (5) ◽  
pp. 649-658 ◽  
Author(s):  
Jean T. Shope ◽  
Patricia F. Waller ◽  
Trivellore E. Raghunathan ◽  
Sujata M. Patil

2004 ◽  
Author(s):  
Kristina M. Jackson ◽  
Kenneth J. Sher ◽  
John E. Schulenberg

2020 ◽  
Author(s):  
Joseph D. Deak ◽  
D. Angus Clark ◽  
Mengzhen Liu ◽  
C. Emily Durbin ◽  
William G. Iacono ◽  
...  

Objective: Molecular genetic studies of alcohol and nicotine have identified many genome-wide loci. We examined the predictive utility of drinking and smoking polygenic scores (PGS) for alcohol and nicotine use from late childhood to early adulthood, substance-specific versus broader-liability PGS effects, and if PGS performance varied between consumption versus pathological use. Methods: Latent growth curve models with structured residuals were used to assess the predictive utility of drinks per week and regular smoking PGS for measures of alcohol and nicotine consumption and problematic use from age 14 to 34. PGSs were generated from the largest discovery sample for alcohol and nicotine use to date (i.e., GSCAN), and examined for associations with alcohol and nicotine use in the Minnesota Twin Family Study (N=3225).Results: The drinking PGS was a significant predictor of age 14 problematic alcohol use and increases in problematic use during young adulthood. The smoking PGS was a significant predictor for all nicotine use outcomes. After adjusting for the effects of both PGSs, the smoking PGS demonstrated incremental predictive utility for most alcohol use outcomes and remained a significant predictor of nicotine use trajectories. Conclusions: Higher PGS for drinking and smoking were associated with more problematic levels of substance use longitudinally. The smoking PGS seems to capture both nicotine-specific and non-specific genetic liability for substance use, and may index genetic risk for broader externalizing behavior. Validation of PGS within longitudinal designs may have important clinical implications should future studies support the clinical utility of PGS for substance use disorders.


Author(s):  
Margaret H. Lloyd Sieger

Children in foster care due to parental substance use disorder are at high risk for delayed permanency. Understudied is the effect of foster care factors on these children’s exits from care. This study analyzed 10 years of federal child welfare data to understand the effect of foster care placement, provider, and support factors for this vulnerable group. Results revealed that several foster care variables influenced time to, and likelihood of, permanency for children with substance-related removals. Foster care setting, foster parent age and race, and several types of federal supports affected permanency trajectories. Children in homes receiving more federal supports were less likely to achieve permanency, suggesting the insufficiency of these supports to counteract the effects of socioeconomic risk on permanency.


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