Can baseline C-reactive protein level predict functional outcome in acute ischaemic stroke? A meta-analysis

Biomarkers ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 525-532
Author(s):  
Ziyi Hu ◽  
Junyu Lai ◽  
Lisha Chen ◽  
Ying Yi ◽  
Renliang Li ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Functional Outcome ◽  
Acute Ischaemic Stroke ◽  
Protein Level ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Contrast extravasation and outcome of endovascular therapy in acute ischaemic stroke: a systematic review and meta-analysis

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e044917
Author(s):  
Tao Xu ◽  
You Wang ◽  
Jinxian Yuan ◽  
Yangmei Chen ◽  
Haiyan Luo
Keyword(s):  
Systematic Review ◽  
Ischaemic Stroke ◽  
Functional Outcome ◽  
Endovascular Therapy ◽  
Acute Ischaemic Stroke ◽  
Data Extraction ◽  
Meta Analysis ◽  
Poor Functional Outcome ◽  
Eligibility Criteria ◽  
Contrast Extravasation

ObjectiveContrast extravasation (CE) after endovascular therapy (EVT) is commonly present in acute ischaemic stroke (AIS) patients. Substantial uncertainties remain about the relationship between CE and the outcomes of EVT in patients with AIS. Therefore, we aimed to evaluate this association.DesignA systematic review and meta-analysis of published studies were performed.Data sourceWe systematically searched the Medline and Embase databases for relevant clinical studies. The last literature search in databases was performed in June 2020.Eligibility criteria for study selectionWe included studies exploring the associations between CE and the outcomes of EVT in patients with AIS undergoing EVT.Data extraction and synthesisTwo reviewers extracted relevant information and data from each article independently. We pooled ORs with CIs using a random-effects meta-analysis to calculate the associations between CE and outcomes of EVT. The magnitude of heterogeneity between estimates was quantified with the I2 statistic with 95% CIs.ResultsFifteen observational studies that enrolled 1897 patients were included. Patients with CE had higher risks of poor functional outcome at discharge (2.38, 95% CI 1.45 to 3.89 p=0.001; n=545) and poor functional outcome at 90 days (OR 2.16, 95% CI 1.20 to 3.90; n=1194). We found no association between CE and in-hospital mortality (OR 0.95, 95% CI 0.27 to 3.30; n=376) or 90-day mortality (OR 1.38, 95% CI 0.81 to 2.36; n=697) after EVT. Moreover, CE was associated with higher risks of post-EVT intracranial haemorrhage (ICH) (OR 6.68, 95% CI 3.51 to 12.70; n=1721) and symptomatic ICH (OR 3.26, 95% CI 1.97 to 5.40; n=1092).ConclusionsThis systematic review and meta-analysis indicates that in patients with AIS undergoing EVT, CE is associated with higher risks of unfavourable functional outcomes and ICH. Thus, we should pay more attention to CE in patients with AIS undergoing EVT.

Prognostic value of pre-therapy C-reactive protein level in diffuse large B-cell lymphoma: a meta-analysis

2018 ◽  
Vol 60 (2) ◽  
pp. 358-366 ◽  
Author(s):  
Wenqiong Qin ◽  
Qiang Yuan ◽  
Jingkui Wu ◽  
Haonan Yu ◽  
Ying Wang ◽  
...  
Keyword(s):  
B Cell ◽  
Protein Level ◽  
Prognostic Value ◽  
Cell Lymphoma ◽  
Meta Analysis ◽  
B Cell Lymphoma ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals Relationship between C-Reactive Protein Level and Diabetic Retinopathy: A Systematic Review and Meta-Analysis

PLoS ONE ◽  
2015 ◽  
Vol 10 (12) ◽  
pp. e0144406 ◽  
Author(s):  
Jian Song ◽  
Song Chen ◽  
Xiaoting Liu ◽  
Hongtao Duan ◽  
Jiahui Kong ◽  
...  
Keyword(s):  
Systematic Review ◽  
Diabetic Retinopathy ◽  
Protein Level ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Reactive Protein

Effects of ginseng on C-reactive protein level: A systematic review and meta-analysis of clinical trials

2019 ◽  
Vol 45 ◽  
pp. 98-103 ◽  
Author(s):  
Somayeh Saboori ◽  
Ebrahim Falahi ◽  
Esmaeil Yousefi Rad ◽  
Omid Asbaghi ◽  
Mohammad Zeinali Khosroshahi
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Protein Level ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Reactive Protein
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