scholarly journals A feasibility randomised control trial of individual cognitive stimulation therapy for dementia: impact on cognition, quality of life and positive psychology

2020 ◽  
pp. 1-9
Author(s):  
Luke Gibbor ◽  
Lycia Forde ◽  
Lauren Yates ◽  
Stavros Orfanos ◽  
Christina Komodromos ◽  
...  
2017 ◽  
Vol 9 (3-2) ◽  
Author(s):  
Stella Wong Jing Yong ◽  
Low Sew Kim ◽  
Pheh Kai Shuen

The Malaysian government estimated that in 2013, 5.5% of the Malaysian population comprises of senior citizens aged 60 years old and above. Recent research had revealed that 14.3% of the older Malaysians are at risk of Major Neurocognitive Disorder (MND; also known as dementia). As the elderly population increases gradually in the country, the chances of them suffering from MND are also expected to increase. MND is often associated with a decline in memory or thinking skills which are severe enough to affect the ability to perform everyday activities among those who are diagnosed with these symptoms. Cognitive Stimulation Therapy (CST) is a brief treatment for those suffering from mild to moderate MND. However, the efficacy of this treatment has not been evident in Malaysia.The aim of the present study is to identify the effectiveness of CST in stabilizing the declination of cognitive functions, as well as improving the quality of life among elderly suffering from mild to moderate MND. Thirty elderly diagnosed with mild and moderate MND will be invited to participate in a single group pre-post trial, involving a 45 minute CST treatment to be administered for 14 weeks on a regular weekly basis. The participants will be selected from residents of care centers elderly at Klang Valley area. The outcomes and effectiveness of the CST will be determined by the Montreal Cognitive Assessment (MoCA), and Quality of Life-Alzheimer’s Disease (QOL-AD). The former instrument will be used to examine the cognitive abilities of the elderly, while the latter will be used to determine issues related to the quality of life based on the participant and caregivers rating report. As the CST efficacies has been proven in several countries such as the United Kingdom, Hong Kong and Japan, the present study anticipates that it will also be effective in the Malaysia context and helps in treating MND.


2019 ◽  
Vol 12 ◽  
pp. 175628641985221 ◽  
Author(s):  
Iracema Leroi ◽  
Sabina Vatter ◽  
Lesley-Anne Carter ◽  
Sarah J. Smith ◽  
Vasiliki Orgeta ◽  
...  

Cognitive stimulation therapy (CST) is widely used with people with dementia, but there is no evidence of its efficacy in mild cognitive impairment or dementia in Parkinson’s disease (PD-MCI; PDD) or dementia with Lewy bodies (DLB). We aimed to explore the impact of ‘CST-PD’, which is home-based, individualized CST adapted for this population. In a single-blind, randomized controlled exploratory pilot trial (RCT), we randomized 76 participant–dyads [PD-MCI ( n = 15), PDD ( n = 40), DLB ( n = 21) and their care partners] to CST-PD or treatment as usual (TAU). CST-PD involves home-based cognitively stimulating and engaging activities delivered by a trained care partner. Exploratory outcomes at 12 weeks included cognition (Addenbrooke’s Cognitive Evaluation; ACE-III), neuropsychiatric symptoms and function. In care partners, we assessed burden, stress and general health status. Relationship quality and quality of life were assessed in both dyad members. At 12 weeks, the ACE-III showed a nonstatistically significant improvement in the CST-PD group compared with the TAU group, although neuropsychiatric symptoms increased significantly in the former. In contrast, care partners’ quality of life ( d = 0.16) and relationship quality (‘satisfaction’, d = 0.01; ‘positive interaction’, d = 0.55) improved significantly in the CST-PD group, and care burden ( d = 0.16) and stress ( d = 0.05) were significantly lower. Qualitative findings in the CST-PD recipients revealed positive ‘in the moment’ responses to the intervention, supporting the quantitative results. In conclusion, care-partner-delivered CST-PD may improve a range of care-partner outcomes that are important in supporting home-based care. A full-scale follow-up RCT to evaluate clinical and cost effectiveness is warranted.


BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e030933 ◽  
Author(s):  
Aimee Spector ◽  
Charlotte R Stoner ◽  
Mina Chandra ◽  
Sridhar Vaitheswaran ◽  
Bharath Du ◽  
...  

IntroductionIn low/middle-income countries (LMICs), the prevalence of people diagnosed with dementia is expected to increase substantially and treatment options are limited, with acetylcholinesterase inhibitors not used as frequently as in high-income countries (HICs). Cognitive stimulation therapy (CST) is a group-based, brief, non-pharmacological intervention for people with dementia that significantly improves cognition and quality of life in clinical trials and is cost-effective in HIC. However, its implementation in other countries is less researched. This protocol describes CST-International; an implementation research study of CST. The aim of this research is to develop, test, refine and disseminate implementation strategies for CST for people with mild to moderate dementia in three LMICs: Brazil (upper middle-income), India (lower middle-income) and Tanzania (low-income).Methods and analysisFour overlapping phases: (1) exploration of barriers to implementation in each country using meetings with stakeholders, including clinicians, policymakers, people with dementia and their families; (2) development of implementation plans for each country; (3) evaluation of implementation plans using a study of CST in each country (n=50, total n=150). Outcomes will include adherence, attendance, acceptability and attrition, agreed parameters of success, outcomes (cognition, quality of life, activities of daily living) and cost/affordability; (4) refinement and dissemination of implementation strategies, enabling ongoing pathways to practice which address barriers and facilitators to implementation.Ethics and disseminationEthical approval has been granted for each country. There are no documented adverse effects associated with CST and data held will be in accordance with relevant legislation. Train the trainer models will be developed to increase CST provision in each country and policymakers/governmental bodies will be continually engaged with to aid successful implementation. Findings will be disseminated at conferences, in peer-reviewed articles and newsletters, in collaboration with Alzheimer’s Disease International, and via ongoing engagement with key policymakers.


2003 ◽  
Vol 183 (3) ◽  
pp. 248-254 ◽  
Author(s):  
Aimee Spector ◽  
Lene Thorgrimsen ◽  
Bob Woods ◽  
Lindsay Royan ◽  
Steve Davies ◽  
...  

BackgroundA recent Cochrane review of reality orientation therapy identified the need for large, well-designed, multi-centre trials.AimsTo test the hypothesis that cognitive stimulation therapy (CST) for older people with dementia would benefit cognition and quality of life.MethodA single-blind, multi-centre, randomised controlled trial recruited 201 older people with dementia. The main outcome measures were change in cognitive function and quality of life. An intention-to-treat analysis used analysis of covariance to control for potential variability in baseline measures.ResultsOne hundred and fifteen people were randomised within centres to the intervention group and 86 to the control group. At follow-up the intervention group had significantly improved relative to the control group on the Mini-Mental State Examination (P=0.044), the Alzheimer's Disease Assessment Scale – Cognition (ADAS–Cog) (P=0.014) and Quality of Life – Alzheimer's Disease scales (P=0.028). Using criteria of 4 points or more improvement on the ADAS–Cog the number needed to treat was 6 for the intervention group.ConclusionThe results compare favourably with trials of drugs for dementia. CST groups may have worthwhile benefits for many people with dementia.


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