Mayo's Older African Americans Normative Studies: Norms for Boston Naming Test, Controlled Oral Word Association, Category Fluency, Animal Naming, Token Test, Wrat-3 Reading, Trail Making Test, Stroop Test, and Judgment of Line Orientation

2005 ◽  
Vol 19 (2) ◽  
pp. 243-269 ◽  
Author(s):  
John A. Lucas ◽  
Robert J. Ivnik ◽  
Glenn E. Smith ◽  
Tanis J. Ferman ◽  
Floyd B. Willis ◽  
...  
2012 ◽  
Vol 18 (6) ◽  
pp. 1086-1090 ◽  
Author(s):  
Myriam Barandiaran ◽  
Ainara Estanga ◽  
Fermín Moreno ◽  
Begoña Indakoetxea ◽  
Ainhoa Alzualde ◽  
...  

AbstractMutations in the progranulin (PGRN) gene have been identified as a cause of frontotemporal dementia (FTD). However, little is known about the neuropsychological abilities of asymptomatic carriers of these mutations. The aim of the study was to assess cognitive functioning in asymptomatic c.709-1G>A PGRN mutation carriers. We hypothesized that poorer neuropsychological performance could be present before the development of clinically significant FTD symptoms. Thirty-two asymptomatic first-degree relatives of FTD patients carrying the c.709-1G>A mutation served as study participants, including 13 PGRN mutation carriers (A-PGRN+) and 19 non-carriers (PGRN-). A neuropsychological battery was administered. We found that the A-PGRN+ participants obtained significantly poorer scores than PGRN- individuals on tests of attention (Trail-Making Test Part A), mental flexibility (Trail-Making Test Part B), and language (Boston Naming Test). Poorer performance on these tests in asymptomatic PGRN mutation carriers may reflect a prodromal phase preceding the onset of clinically significant symptoms of FTD. (JINS, 2012, 18, 1086–1090)


2005 ◽  
Vol 19 (3-4) ◽  
pp. 280-328 ◽  
Author(s):  
Brett A. Steinberg ◽  
Linas A. Bieliauskas ◽  
Glenn E. Smith ◽  
Christopher Langellotti ◽  
Robert J. Ivnik

2020 ◽  
Vol 25 ◽  
pp. 15-29
Author(s):  
Priscilla Ras ◽  
Djaina Satoer ◽  
Geert-Jan Rutten ◽  
Arnaud Vincent ◽  
Evy Visch-Brink

Patiënten met een laaggradig glioom (langzaam groeiende hersentumor) rapporteren vaak woordvindproblemen, terwijl deze met de huidig gebruikte benoemtests in de praktijk vaak niet geobjectiveerd worden. In deze studie worden de resultaten van een sensitieve snelle benoemtest (SBT) voor objecten besproken, toegepast bij deze patiëntengroep. Via deze nieuwe test werden reactietijden verzameld van 18 patiënten met een vermeend laaggradig glioom en van 20 gezonde participanten. Om uit te sluiten dat bij glioompatiënten tragere reactietijden worden gevonden als gevolg van algehele cognitieve traagheid, zijn de resultaten van een test voor cognitieve snelheid (Trail Making Test-A, TMT-A) meegenomen in het onderzoek. De resultaten op de SBT zijn vergeleken met de resultaten op de klinisch veel gehanteerde Boston Naming Test (BNT) om zo de toegevoegde waarde van de SBT te kunnen evalueren. Tevens is het effect van woordfrequentie en Age of Acquisition (AoA) op de benoemtijden onderzocht. Glioompatiënten waren significant langzamer in het benoemen van de objecten dan de gezonde participanten. De tragere reactietijdenwerden niet verklaard door een algeheel tragere verwerkingssnelheid. Ook de BNT-scores konden de lagere reactietijden op de SBT niet verklaren. Een kwalitatieve vergelijking tussen de resultaten van de BNT en de SBT duidde op een hogere sensitiviteit van de SBT voor woordvindproblemen. In de groep gezonde participanten wordt een effect gevonden van woordfrequentie en AoA op de benoemsnelheden, in de patiëntengroep is echter geen effect van deze variabelen waar te nemen. De resultaten laten een duidelijk verschil in benoemsnelheid zien tussen laaggradige glioompatiënten en gezonde participanten, terwijl patiënten zelden een afwijkende score behaalden op de BNT. Het lijkt zinvol om de SBT te gebruiken in de klinische praktijk, waarbij reactietijden als een belangrijk component meegenomen worden voor het diagnosticeren van woordvindproblemen bij glioompatiënten.


Assessment ◽  
2016 ◽  
Vol 25 (4) ◽  
pp. 498-512 ◽  
Author(s):  
Samuel Adjorlolo

The sociocultural differences between Western and sub-Saharan African countries make it imperative to standardize neuropsychological tests in the latter. However, Western-normed tests are frequently administered in sub-Saharan Africa because of challenges hampering standardization efforts. Yet a salient topical issue in the cross-cultural neuropsychology literature relates to the utility of Western-normed neuropsychological tests in minority groups, non-Caucasians, and by extension Ghanaians. Consequently, this study investigates the diagnostic accuracy, sensitivity, and specificity of executive function (EF) tests (The Stroop Test, Trail Making Test, and Controlled Oral Word Association Test), and a Revised Quick Cognitive Screening Test (RQCST) in a sample of 50 patients diagnosed with moderate traumatic brain injury and 50 healthy controls in Ghana. The EF test scores showed good diagnostic accuracy, with area under the curve (AUC) values of the Trail Making Test scores ranging from .746 to .902. With respect to the Stroop Test scores, the AUC values ranged from .793 to .898, while Controlled Oral Word Association Test had AUC value of .787. The RQCST scores discriminated between the groups, with AUC values ranging from .674 to .912. The AUC values of composite EF score and a neuropsychological score created from EF and RQCST scores were .936 and. 942, respectively. Additionally, the Stroop Test, Trail Making Test, EF composite score, and RQCST scores showed good to excellent sensitivities and specificities. In general, this study has shown that commonly used EF tests in Western countries have diagnostic accuracy, sensitivity, and specificity when administered in Ghanaian samples. The findings and implications of the study are discussed.


2020 ◽  
Vol 10 (10) ◽  
pp. 702 ◽  
Author(s):  
Jan Wilke ◽  
Vanessa Stricker ◽  
Susanne Usedly

Resistance exercise has been demonstrated to improve brain function. However, the optimal workout characteristics are a matter of debate. This randomized, controlled trial aimed to elucidate differences between free-weight (REfree) and machine-based (REmach) training with regard to their ability to acutely enhance cognitive performance (CP). A total of n = 46 healthy individuals (27 ± 4 years, 26 men) performed a 45-min bout of REfree (military press, barbell squat, bench press) or REmach (shoulder press, leg press, chest press). Pre- and post-intervention, CP was examined using the Stroop test, Trail Making Test and Digit Span test. Mann–Whitney U tests did not reveal between-group differences for performance in the Digit Span test, Trail Making test and the color and word conditions of the Stroop test (p > 0.05). However, REfree was superior to REmach in the Stroop color-word condition (+6.3%, p = 0.02, R = 0.35). Additionally, REfree elicited pre-post changes in all parameters except for the Digit Span test and the word condition of the Stroop test while REmach only improved cognitive performance in part A of the Trail Making test. Using free weights seems to be the more effective RE method to acutely improve cognitive function (i.e., inhibitory control). The mechanisms of this finding merit further investigation.


2009 ◽  
Vol 24 (4) ◽  
pp. 343-354 ◽  
Author(s):  
J. Pena-Casanova ◽  
S. Quinones-Ubeda ◽  
N. Gramunt-Fombuena ◽  
M. Aguilar ◽  
L. Casas ◽  
...  

CNS Spectrums ◽  
2017 ◽  
Vol 23 (1) ◽  
pp. 10-23 ◽  
Author(s):  
Ahmed Elgebaly ◽  
Mohamed Elfil ◽  
Attia Attia ◽  
Mayar Magdy ◽  
Ahmed Negida

BackgroundStudies comparing subthalamus (STN) and globus pallidus internus (GPi) deep brain stimulation (DBS) for the management of Parkinson’s disease in terms of neuropsychological performance are scarce and heterogeneous. Therefore, we performed a systematic review and metaanalysis to compare neuropsychological outcomes following STN DBS versus GPi DBS.MethodsA computer literature search of PubMed, the Web of Science, and Cochrane Central was conducted. Records were screened for eligible studies, and data were extracted and synthesized using Review Manager (v. 5.3 for Windows).ResultsSeven studies were included in the qualitative synthesis. Of them, four randomized controlled trials (n=345 patients) were pooled in the metaanalysis models. The standardized mean difference (SMD) of change in the Stroop color-naming test favored the GPi DBS group (SMD=–0.31,p=0.009). However, other neuropsychological outcomes did not favor either of the two groups (Stroop word-reading:SMD=–0.21,p=0.08; the Wechsler Adult Intelligence Scale (WAIS) digits forward:SMD=0.08,p=0.47; Trail Making Test Part A:SMD=–0.05,p=0.65; WAIS–R digit symbol:SMD=–0.16,p=0.29; Trail Making Test Part B:SMD=–0.14,p=0.23; Stroop color–word interference:SMD=–0.16,p=0.18; phonemic verbal fluency: bilateral DBSSMD=–0.04,p=0.73, and unilateral DBSSMD=–0.05,p=0.83; semantic verbal fluency: bilateral DBSSMD=–0.09,p=0.37, and unilateral DBSSMD=–0.29,p=0.22; Boston Naming Test:SMD=–0.11,p=0.33; Beck Depression Inventory: bilateral DBSSMD=0.15,p=0.31, and unilateral DBSSMD=0.36,p=0.11).ConclusionsThere was no statistically significant difference in most of the neuropsychological outcomes. The present evidence does not favor any of the targets in terms of neuropsychological performance.


2017 ◽  
Vol 41 (S1) ◽  
pp. s241-s242
Author(s):  
A. Tmava ◽  
I. Eicher ◽  
D.E. Seitz ◽  
S. Mörkl ◽  
C. Blesl ◽  
...  

BackgroundDespite its high effectiveness, electroconvulsive therapy (ECT) is not a widely used method to treat depression. One of the reasons for this could be the fear of cognitive side effects. The aim of this study was to investigate effects of ECT on cognitive function.MethodsWe conducted a prospective study with a sample size of 23 patients (10 male), who met the criteria of treatment-resistant depression according to ICD–10 and gave their informed consent for ECT treatment. Before and after ECT, the following investigations have been performed: Beck depression inventory (BDI), Montgomery-Asberg depression rating scale (MADRS), Mehrfachwahl-Wortschatz-Intelligenztest (MWT-B), trail making test (TMT) A and B, stroop-test, mini mental state examination (MMSE) and the German version of the California verbal learning test (MGT).ResultsAfter ECT treatment, we found highly significant changes of depression-scales BDI (P = 0.028) and MADR-Scale (P = 0.001). IQ as measured by the MWT-B (P = 0.851), executive functions as measured by trail making test A (P = 0.568) and B (P = 0.372) and stroop-test, memory functions as measured by the MGT (P = 0.565) (Figure 1) and MMSE (P = 0.678) did not differ significantly after ECT treatment.ConclusionThere were no significant differences in cognitive function before and after ECT treatment. To confirm these findings, it would be necessary to perform larger studies.Disclosure of interestThe authors have not supplied their declaration of competing interest.


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