New Generation Large Aircrafts became a new member of China large airports. However, its heavy weight and high contact pressure would have great impact on the flexible runway pavement. in this paper, based on the multilayered elastic theory, the tensile stress distribution under different airplane was studied to obtain the critical load positions. Furthermore, parameter sensitivity analysis was conducted, including thickness and modulus of Asphalt Stabilized Base (ATB) layer. Results indicated that increasing ATB thickness can only decrease the tensile stress a little, and increasing the modulus of the ATB layer will be more efficient than increasing its thickness. Finally pavement design suggestions composing of both the structural and material considerations were proposed.