Efficient disassembly operation is considered a promising approach toward waste reduction and End-of-Use (EOU) product recovery. However, many kinds of uncertainty exist during the product lifecycle which make disassembly decision a complicated process. The optimum disassembly sequence may vary at different milestones depending on the purpose of disassembly (repair, maintenance, reuse and recovery), product quality conditions and external factors such as consumer preference, and the market value of EOU components. A disassembly sequence which is optimum for one purpose may not be optimum in future life cycles or other purposes. Therefore, there is a need for incorporating the requirements of the entire product life-cycle when obtaining the optimum disassembly sequence. This paper applies a fuzzy method to quantify the probability that each feasible disassembly transition will be needed during the entire product lifecycle. Further, the probability values have been used in an optimization model to find the disassembly sequence with maximum likelihood. An example of vacuum cleaner is used to show how the proposed method can be applied to quantify different users’ evaluation on the relative importance of disassembly selection criteria as well as the probability of each disassembly operation.