Practices of publication and experimentation in the Atlantic world inspired physicians, natural philosophers, clerics, and others conversant in learning about climatic conditions, sanitation, and the sciences of anatomy, botany, chemistry, and statistics to forge connections with one another and with lay communities to improve medical care in New Spain. Beginning in 1768, the rise of a scientific periodical press in New Spain provided a novel means to collect and disseminate learning about health care, natural remedies, and scientific developments. In effect reproducing a conceit of colonial healing manuals, the print culture of the Enlightenment went further to shape a repository of vernacular knowledge from correspondents in cities, towns, and villages. Ultimately this venue failed to incorporate, as some hoped, a broader sector of the lower classes into scientific and medical practice.