Development of a Guinea Pig Model for Low-Dose, Long-Term Exposure to Organophosphorus Nerve Agents

2004 ◽  
Vol 14 (3) ◽  
pp. 183-194 ◽  
Author(s):  
Chessley R. Atchison ◽  
Robert E. Sheridan ◽  
Steven M. Duniho ◽  
Tsung-Ming Shih
1999 ◽  
Vol 19 (8) ◽  
pp. 887-894 ◽  
Author(s):  
Yu-Ichiro Satoh ◽  
Kyoko Kasama ◽  
Mikiko Kuwabara ◽  
Hong-Yan Diao ◽  
Hirofumi Nakajima ◽  
...  

2001 ◽  
Vol 80 (3) ◽  
pp. 213-226 ◽  
Author(s):  
Mark A Chambers ◽  
Ann Williams ◽  
Dolores Gavier-Widén ◽  
Adam Whelan ◽  
Catherine Hughes ◽  
...  

2013 ◽  
Vol 21 (2) ◽  
pp. 253-255 ◽  
Author(s):  
Robert C. Seid ◽  
Christoph Reinisch ◽  
Robert Schlegl ◽  
Michael Moehlen ◽  
Andreas Meinke ◽  
...  

ABSTRACTDry tetanus toxoid (TTx) patches were formulated without any adjuvant, with excipients to impart antigen stabilization and to enhance skin delivery. The booster effects of the TTx patches were assessed using a guinea pig model. The study revealed significant rises in TTx IgG titers induced by the TTx patches after a low-dose subcutaneous (s.c.) prime with TTx adsorbed to aluminum hydroxide. The TTx patch can therefore be considered an effective alternative to a subcutaneous booster.


2013 ◽  
Vol 18 (6) ◽  
pp. 392-405 ◽  
Author(s):  
Jason Lee ◽  
Hudaifa Ismail ◽  
Jun Ho Lee ◽  
Gordana Kel ◽  
Jonathan O'Leary ◽  
...  

2012 ◽  
Vol 20 (6) ◽  
pp. 852-853 ◽  
Author(s):  
Shlomit Dachir ◽  
Maayan Cohen ◽  
Dikla Kamus-Elimeleh ◽  
Eliezer Fishbine ◽  
Rita Sahar ◽  
...  

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