Studies on Lanthanide(III) Ternary Mixed-Ligand Complexes with N-(2-Propionic Acid)-Salicyloyl Hydrazone and Isonicotinic Acid: Synthesis, Characterization, and Antibacterial Activities

2008 ◽  
Vol 38 (8) ◽  
pp. 642-646 ◽  
Author(s):  
F.-Y. Chen ◽  
Sh.-Y. He
Keyword(s):  
Propionic Acid ◽  
Isonicotinic Acid ◽  
Acid Synthesis ◽  
Antibacterial Activities ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes

scholarly journals Syntheses of Coordination Compounds of 2-Amino-3-Methylbutanoic Acid Their Mixed Ligand Complexes and Antibacterial Activities

2020 ◽  
Vol 10 (03) ◽  
pp. 67-85
Author(s):  
Temitayo O. Aiyelabola ◽  
Iyanuoluwa E. Okunade ◽  
Johan H. L. Jordaan ◽  
Daniel P. Otto
Keyword(s):  
Coordination Compounds ◽  
Antibacterial Activities ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes

scholarly journals Mono-and Binuclear Cobalt(II) Mixed Ligand Complexes of 2,2’-Bipyridine and Ethylenediamine: Synthesis, Characterization and Biological Application

2021 ◽  
Vol 12 (2) ◽  
pp. 1962-1973
Keyword(s):  
Antibacterial Activities ◽  
Spectroscopic Technique ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes ◽  
Diffusion Method ◽  
E Coli ◽  
Precursor Complex ◽  
Chloride Determination ◽  
Ft Ir ◽  
Physicochemical Methods

Antibiotic resistance of pathogens to the current commercially available drugs is a serious problem. To curve this problem, the discovery of active compounds with a new mode of action is insistent. In line with this, we report two new complexes; mononuclear [Co(L1)2(L2)(H2O)]Cl2 and binuclear [Co2(L1)4(L2)(H2O)2]Cl4 using precursor complex, [Co(L1)2(H2O)2]Cl2, synthesized before; where L1: 2,2’-bipyridine and L2: ethylenediamine. The precursor complex was prepared from CoCl2.6H2O and L1 in ethanol, treated with a different mole of L2 under optimized reaction conditions to give the corresponding mono-and binuclear cobalt(II) mixed ligand complexes. These complexes were characterized using the spectroscopic technique (ICP-OES, UV-Vis, FT-IR) and physicochemical methods (chloride determination, thermal analysis, and conductance measurement). Their antibacterial activities were also tested against two Gram-negative (Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae)) and two Gram-positive (Staphylococcus aureus (S. aureus), Streptococcus pyogenes (S. pyogenes)) bacteria using the disc diffusion method. The new complexes showed better activities against K. pneumoniae than the reference Gentamycin. Furthermore, [Co(L1)2(L2)(H2O)]Cl2 demonstrated better activity than Gentamycin against S. aureus and E. coli.

Sign in / Sign up

Export Citation Format

Share Document