Optimizing ZnO/CdS Nano Composite Controlled by Fe Doping Towards Efficiency in Water Treatment and Antimicrobial Activity

Nanocrystalline composite zinc oxide (ZnO) and CdS with Fe doping thin films grown on glass substrate by chemical method. The parameters like temperature of the solution, UV exposure, pH of solution, immersion time, immersion cycles, have been controlled and standardized for nanocrystalline film. The synthesis NPs were analyzed by X-ray diffraction (XRD). Rietveld method shows that Fe-doped composite ZnO/CdS is a single pure phase and wurtzite structure. Samples were analyzed by sophisticated various instrument like XRD, UV- Visible spectrometer, HRTEM, HRSEM and composition was analyzed by EDX attached with HRTEM. The band gap was calculated by absorption spectroscopy and found that absorption was blue-shifted. The electron structure shows that doping changes the crystal structure and transition level create better efficiency and creates octahedral symmetry. The antibacterial studies showed that the 5.0 wt% Fe-doped exhibited maximum antibacterial effect.

Antibacterial Studies of Penicillin G Loaded Carboxylic Cellulose Acetate Nanoparticles

Cellulose acetate nanoparticles (CCA NPs) with mean particles sizes of 97 nm were synthesized via the nanoprecipitation process. The antibacterial properties of these CCA NPs were evaluated against Gram (+) and Gram (-) bacteria, respectively. The CCA NPs exhibited good antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA) (+), Staphylococcus epidermis (+), Escherichia coli (-), Bacillus cereus (+), and Salmonella typhimurium (-) in range of MIC of 2.5×102 to 5.0×102 µg.mL-1 and MBC of 5.0×102 to 1.0×103 µg.mL-1. Penicillin G (PenG)-loaded CCA NPs demonstrated synergistic antibacterial activities against Gram (+) and Gram (-) bacteria. PenG-loaded CCA NPs also exhibited promising antimicrobial activity against the Methicillin-resistant staphylococcus aureus (MRSA) superbug, which is resistant to penicillin G. These promising antibacterial properties suggested that CCA NPs could potentially serve as an alternative potent antimicrobial agent for both Gram (+) and Gram (-) bacteria as well as the superbug MRSA.