Targeting AMPK-ULK1-mediated autophagy for combating BET inhibitor resistance in acute myeloid leukemia stem cells

Ji Eun Jang; Ju-In Eom; Hoi-Kyung Jeung; June-Won Cheong; Jung Yeon Lee; Jin Seok Kim; Yoo Hong Min

doi:10.1080/15548627.2016.1278328

Targeting AMPK-ULK1-mediated autophagy for combating BET inhibitor resistance in acute myeloid leukemia stem cells

Autophagy ◽

10.1080/15548627.2016.1278328 ◽

2017 ◽

Vol 13 (4) ◽

pp. 761-762 ◽

Cited By ~ 28

Author(s):

Ji Eun Jang ◽

Ju-In Eom ◽

Hoi-Kyung Jeung ◽

June-Won Cheong ◽

Jung Yeon Lee ◽

...

Keyword(s):

Stem Cells ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Stem Cells ◽

Bet Inhibitor ◽

Inhibitor Resistance ◽

Acute Myeloid

Download Full-text

AMPK–ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-16-1903 ◽

2016 ◽

Vol 23 (11) ◽

pp. 2781-2794 ◽

Cited By ~ 46

Author(s):

Ji Eun Jang ◽

Ju-In Eom ◽

Hoi-Kyung Jeung ◽

June-Won Cheong ◽

Jung Yeon Lee ◽

...

Keyword(s):

Stem Cells ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Stem Cells ◽

Bet Inhibitor ◽

Acute Myeloid

Download Full-text

Faculty Opinions recommendation of Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718326593.793493199 ◽

2014 ◽

Author(s):

Xiaoyan Jiang ◽

Katharina Rothe

Keyword(s):

Stem Cells ◽

Acute Myeloid Leukemia ◽

Growth Factor ◽

Myeloid Leukemia ◽

Growth Factor Receptor ◽

Leukemia Stem Cells ◽

Human Acute Myeloid Leukemia ◽

Acute Myeloid

Download Full-text

Cell Surface Marker Phenotypes and Gene Expression Profiles of Murine Radiation-Induced Acute Myeloid Leukemia Stem Cells are Similar to Those of Common Myeloid Progenitors

Radiation Research ◽

10.1667/rr2374.1 ◽

2011 ◽

Vol 176 (3) ◽

pp. 311-322 ◽

Cited By ~ 13

Author(s):

Tokuhisa Hirouchi ◽

Miyuki Akabane ◽

Satoshi Tanaka ◽

Ignacia Braga-Tanaka ◽

Akiko Todate ◽

...

Keyword(s):

Gene Expression ◽

Stem Cells ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Expression Profiles ◽

Gene Expression Profiles ◽

Surface Marker ◽

Leukemia Stem Cells ◽

Radiation Induced ◽

Acute Myeloid

Download Full-text

Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia: Yin and Yang

Cancer Biology and Medicine ◽

10.20892/j.issn.2095-3941.2016.0023 ◽

2016 ◽

Vol 13 (2) ◽

pp. 248-259 ◽

Cited By ~ 44

Author(s):

Hong-Sheng Zhou ◽

Bing Z. Carter ◽

Michael Andreeff ◽

Bing Z. Carter ◽

...

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Stem Cells ◽

Bone Marrow Niche ◽

Yin And Yang ◽

Acute Myeloid

Download Full-text

Ex Vivo Assays to Study Self-Renewal and Long-Term Expansion of Genetically Modified Primary Human Acute Myeloid Leukemia Stem Cells

Leukemia - Methods in Molecular Biology™ ◽

10.1007/978-1-59745-418-6_14 ◽

2009 ◽

pp. 287-300 ◽

Cited By ~ 18

Author(s):

Jan Jacob Schuringa ◽

Hein Schepers

Keyword(s):

Stem Cells ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Ex Vivo ◽

Genetically Modified ◽

Leukemia Stem Cells ◽

Self Renewal ◽

Human Acute Myeloid Leukemia ◽

Acute Myeloid

Download Full-text

Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells

Cell Reports ◽

10.1016/j.celrep.2020.107688 ◽

2020 ◽

Vol 31 (9) ◽

pp. 107688 ◽

Cited By ~ 1

Author(s):

Josephine Wesely ◽

Andriana G. Kotini ◽

Franco Izzo ◽

Hanzhi Luo ◽

Han Yuan ◽

...

Keyword(s):

Stem Cells ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Stem Cells ◽

Human Leukemia ◽

Acute Myeloid

Download Full-text

To PARP or not to PARP?—Toward sensitizing acute myeloid leukemia stem cells to immunotherapy

The EMBO Journal ◽

10.15252/embj.2019103479 ◽

2019 ◽

Vol 38 (21) ◽

Cited By ~ 4

Author(s):

Benjamin Heyman ◽

Catriona Jamieson

Keyword(s):

Stem Cells ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Stem Cells ◽

Acute Myeloid

Download Full-text

Abstract 4619: PF-04449913 reverts multi drug resistance (MDR) by a strong down-regulation ofABCA2andBCL2on leukemia stem cells in phase I acute myeloid leukemia and chronic myeloid leukemia treated patients

10.1158/1538-7445.am2012-4619 ◽

2012 ◽

Author(s):

Cristina Papayannidis ◽

Viviana Guadagnuolo ◽

Ilaria Iacobucci ◽

Sandra Durante ◽

Carolina Terragna ◽

...

Keyword(s):

Stem Cells ◽

Drug Resistance ◽

Acute Myeloid Leukemia ◽

Chronic Myeloid Leukemia ◽

Phase I ◽

Myeloid Leukemia ◽

Leukemia Stem Cells ◽

Multi Drug Resistance ◽

Down Regulation ◽

Acute Myeloid

Download Full-text

Abstract 469: Selective targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells

10.1158/1538-7445.am2020-469 ◽

2020 ◽

Author(s):

Inge Van der Werf ◽

Phoebe Mondala ◽

Raymond Diep ◽

Larisa Balaian ◽

Cayla Mason ◽

...

Keyword(s):

Stem Cells ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Stem Cells ◽

Pediatric Acute Myeloid Leukemia ◽

Selective Targeting ◽

Acute Myeloid

Download Full-text

Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia

Nature Medicine ◽

10.1038/s41591-018-0233-1 ◽

2018 ◽

Vol 24 (12) ◽

pp. 1859-1866 ◽

Cited By ~ 150

Author(s):

Daniel A. Pollyea ◽

Brett M. Stevens ◽

Courtney L. Jones ◽

Amanda Winters ◽

Shanshan Pei ◽

...

Keyword(s):

Stem Cells ◽

Acute Myeloid Leukemia ◽

Energy Metabolism ◽

Myeloid Leukemia ◽

Leukemia Stem Cells ◽

Acute Myeloid

Download Full-text