Solid dispersions are one of the most promising strategies to improve the oral bioavailability of poorly water soluble drugs.
By reducing drug particle size to the absolute minimum, and hence improving drug wettability, bioavailability may be
significantly improved. This article reviews the various preparation techniques for solid dispersion and compiles some of
the recent technology transfers. The different types of solid dispersions based on the molecular arrangement have been
highlighted. Some of the practical aspects to be considered for the preparation of solid dispersions, such as selection of
carrier, solvent and methods of physicochemical characterization, along with an insight into the molecular arrangement of
drugs in solid dispersions are also discussed. In this review, it is intended to discuss the recent advances related on the area
of solid dispersions.
