Association of maternal blood lead concentration with the risk of small for gestational age: A dose-response meta-analysis

2021 ◽  
pp. 1-9
Author(s):  
Ahmad Habibian Sezavar ◽  
Bahman Pourhassan ◽  
Nader Rahimi Kakavandi ◽  
Mohammad Reza Hooshangi Shayeste ◽  
Morteza Abyadeh
Keyword(s):  
Dose Response ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Lead Concentration ◽  
Meta Analysis ◽  
Blood Lead ◽  
Maternal Blood ◽  
Blood Lead Concentration

Fetal and Infant Lead Exposure: Effects on Growth in Stature

PEDIATRICS ◽  
1989 ◽  
Vol 84 (4) ◽  
pp. 604-612
Author(s):  
Rakesh Shukla ◽  
Robert L. Bornschein ◽  
Kim N. Dietrich ◽  
C. R. Buncher ◽  
Omer G. Berger ◽  
...  
Keyword(s):  
Growth Rate ◽  
Longitudinal Analysis ◽  
Lead Exposure ◽  
Growth Rates ◽  
Lead Concentration ◽  
Blood Lead ◽  
Maternal Blood ◽  
Blood Lead Concentration ◽  
Blood Lead Levels ◽  
Lead Levels

The growth of a cohort of 260 infants was prospectively followed up from birth. Blood lead and stature measurements were obtained every 3 months until 15 months of age. Fetal lead exposure was indexed by measuring lead in maternal blood during pregnancy. A longitudinal analysis revealed that covariate adjusted growth rates in stature were negatively related to the infants' postnatal blood lead concentration, as indexed by increase in average blood lead values from 3 to 15 months. However, this relationship between growth rate and change in blood lead concentration was evidenced only among those infants whose mothers had prenatal blood lead levels greater than the maternal cohort median of 7.7 γg/dL (P = .01). The expected stature of a child born to a mother with a prenatal blood lead concentration more than 7.7 γg/dL is about 2 cm shorter at 15 months of age if, postnatally, the infant incurred a 10-γg/dL blood lead increase during the 3-to 15-month interval of life, compared with an infant who has no increase.

Blood lead concentration among oral/inhaled opium users: systematic review and meta-analysis

2021 ◽  
Vol 51 (1) ◽  
pp. 24-35 ◽  
Author(s):  
Vahid Farnia ◽  
Maghdad Pirsaheb ◽  
Namam Ali Azadi ◽  
Borhan Mansouri ◽  
Farnaz Radmehr
Keyword(s):  
Systematic Review ◽  
Lead Concentration ◽  
Meta Analysis ◽  
Blood Lead ◽  
Blood Lead Concentration

Maternal and Cord Blood Adiponectin Concentrations in Small for Gestational Age: A Meta-Analysis

2017 ◽  
Vol 72 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Eita Goto
Keyword(s):  
Cord Blood ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
English Language ◽  
Meta Analysis ◽  
Maternal Blood ◽  
Healthy Controls ◽  
Adiponectin Concentration ◽  
Promoting Effect ◽  
Significant Difference

Background: Adiponectin, which may have a growth-promoting effect through its insulin-sensitizing action, is thought to play a key role in fetal growth. This study was performed to determine whether maternal and/or cord blood adiponectin concentrations differ between small for gestational age (SGA) and healthy controls. Methods: Databases were searched to identify good quality English language studies providing the number of SGA and healthy controls, and the means and standard deviations of maternal or cord blood adiponectin concentration in both groups. A meta-analysis was performed to summarize the standardized mean differences (SMDs) in maternal and cord blood adiponectin concentrations between SGA and healthy controls. Results: There was no statistically significant difference in maternal blood adiponectin concentration between SGA and healthy controls (n = 8, p = 0.951). However, cord blood adiponectin concentration was significantly lower in SGA than in healthy controls (n = 6, p = 0.028), and the effect was large (i.e., SMD >0.7). Conclusions: Maternal blood adiponectin concentration is not low in SGA compared with healthy controls. However, SGA shows lower cord blood adiponectin concentration than healthy controls.

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