Circular RNA Expression Profiles Following Negative Pressure Wound Therapy in Burn Wounds with Experimental Pseudomonas aeruginosa Infection

Driveline infections and sepsis are amongst the most common causes of morbidity and mortality in a patient with a left ventricular assist device. In this case, we present a patient with a multi drug resistant pseudomonas aeruginosa driveline exit site infection. Initially, it was treated with dual antibiotics, followed by surgical debridement utilizing Dakin’s solution irrigation and standard negative pressure wound therapy. Wound healing was minimal determined by poor granulation appearance, unchanged size from surgical debridement, purulent drainage, and the wound base remained colonized with multi drug resistant pseudomonas aeruginosa. A novel treatment of VeraFlo negative pressure wound therapy in conjunction with indwelling Dakin’s solution into the wound base was introduced. This treatment resulted in improved granulation appearance, decreased drainage, decreasing in wound size, with positive changes noticeable in 7 days. We suggest that the use of VeraFlo negative pressure wound therapy may be used for treatment for cumbersome driveline infections.

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Negative Pressure Wound Therapy with Instillation Use in Burn Wounds - First Experiences

10.26226/morressier.594bbebfd462b8028d893e0c ◽

2017 ◽

Author(s):

Sigrid Eberwein

Keyword(s):

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Wound Therapy ◽

Burn Wounds

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Negative-Pressure Wound Therapy for Large Burn Wounds

Burns, Infections and Wound Management - Recent Clinical Techniques, Results, and Research in Wounds ◽

10.1007/15695_2018_112 ◽

2018 ◽

pp. 251-259

Author(s):

David E. Varon ◽

Jessica D. Smith ◽

Riyam Mistry ◽

Neel A. Kantak ◽

Eric G. Halvorson

Keyword(s):

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Wound Therapy ◽

Burn Wounds

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Comprehensive analysis of lncRNA and miRNA expression profiles and ceRNA network construction in negative pressure wound therapy

Annals of Translational Medicine ◽

10.21037/atm-21-3626 ◽

2021 ◽

Vol 9 (17) ◽

pp. 1383-1383

Author(s):

Jie Wu ◽

Yong Qin ◽

Zhirui Li ◽

Jiantao Li ◽

Litao Li ◽

...

Keyword(s):

Mirna Expression ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Expression Profiles ◽

Comprehensive Analysis ◽

Wound Therapy ◽

Network Construction ◽

Cerna Network ◽

Mirna Expression Profiles

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Negative pressure wound therapy reduces the motility of Pseudomonas aeruginosa and enhances wound healing in a rabbit ear biofilm infection model

Antonie van Leeuwenhoek ◽

10.1007/s10482-018-1045-5 ◽

2018 ◽

Vol 111 (9) ◽

pp. 1557-1570 ◽

Cited By ~ 3

Author(s):

Wang Guoqi ◽

Li Zhirui ◽

Wang Song ◽

Li Tongtong ◽

Zhang Lihai ◽

...

Keyword(s):

Pseudomonas Aeruginosa ◽

Wound Healing ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Infection Model ◽

Wound Therapy ◽

Rabbit Ear ◽

Biofilm Infection

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An Application of a Negative-Pressure Wound Dressing for Partial- or Full-Thickness Burn Wounds

The International Journal of Lower Extremity Wounds ◽

10.1177/1534734620933439 ◽

2020 ◽

pp. 153473462093343

Author(s):

Yulong Cheng ◽

Zengding Zhou ◽

Huan Hu ◽

Wenbo Li ◽

Yi Liu ◽

...

Keyword(s):

Hospital Stay ◽

Negative Pressure ◽

Medical Records ◽

Wound Dressing ◽

Small Area ◽

Negative Pressure Wound Therapy ◽

Full Thickness ◽

Wound Therapy ◽

Vacuum Suction ◽

Burn Wounds

Negative-pressure wound therapy is widely used in burn populations. Traditionally, negative-pressure devices use persistent vacuum suction, requiring a longer hospital stay. In this study, we applied a novel negative-pressure wound dressing for burn wounds, which eliminates the hospital stay. The medical records of 39 patients with partial-/full-thickness burns treated by negative-pressure wound dressing were retrospectively analyzed. The average burn area, burn degree, healing duration, cost, and incidents during treatment were determined and compared with previous data for conventional therapies. In conclusion, for patients diagnosed with partial-thickness or full-thickness burns and a burn area <34.6 ± 2.21 cm2, the negative-pressure wound dressing is a reliable option, especially for burnt children. Moreover, the negative-pressure wound dressing treatment was not only much cheaper than conventional therapies, but also eliminated hospital stay in patients with small-area deep burn wounds.

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