Acute Atherosis Lesions at the Fetal-Maternal Border: Current Knowledge and Implications for Maternal Cardiovascular Health

Decidua basalis, the endometrium of pregnancy, is an important interface between maternal and fetal tissues, made up of both maternal and fetal cells. Acute atherosis is a uteroplacental spiral artery lesion. These patchy arterial wall lesions containing foam cells are predominantly found in the decidua basalis, at the tips of the maternal arteries, where they feed into the placental intervillous space. Acute atherosis is prevalent in preeclampsia and other obstetric syndromes such as fetal growth restriction. Causal factors and effects of acute atherosis remain uncertain. This is in part because decidua basalis is challenging to sample systematically and in large amounts following delivery. We summarize our decidua basalis vacuum suction method, which facilitates tissue-based studies of acute atherosis. We also describe our evidence-based research definition of acute atherosis. Here, we comprehensively review the existing literature on acute atherosis, its underlying mechanisms and possible short- and long-term effects. We propose that multiple pathways leading to decidual vascular inflammation may promote acute atherosis formation, with or without poor spiral artery remodeling and/or preeclampsia. These include maternal alloreactivity, ischemia-reperfusion injury, preexisting systemic inflammation, and microbial infection. The concept of acute atherosis as an inflammatory lesion is not novel. The lesions themselves have an inflammatory phenotype and resemble other arterial lesions of more extensively studied etiology. We discuss findings of concurrently dysregulated proteins involved in immune regulation and cardiovascular function in women with acute atherosis. We also propose a novel hypothesis linking cellular fetal microchimerism, which is prevalent in women with preeclampsia, with acute atherosis in pregnancy and future cardiovascular and neurovascular disease. Finally, women with a history of preeclampsia have an increased risk of premature cardiovascular disease. We review whether presence of acute atherosis may identify women at especially high risk for premature cardiovascular disease.

A Smart Pest Control System Based on Automated Reverse Aerodynamics and Suction Technology

Many diseases (including malaria, one of the deadliest diseases especially to those living in developing nations which kills hundreds on daily basis) are transmitted by household insects. Mosquitoes, one of these insects, bites humans and sucks their blood and are pathogens of several diseases (especially malaria) which causes ill health and many times lead to death if it is not well treated. This necessitates the need to smartly eliminate them without chemicals, which may be harmful to human health. This research aims at the design and development of a smart insect trap which attracts and contains household insects and pests automatically. The device incorporates a dual power supply that powers and charges the system, sensors which detects the presence of insects and triggers the vacuum suction mechanism automatically, a charge controller for controlling the charging of the installed battery, an ultraviolet light emitting section that lures the insects to the device, a chamber for containment and dehydration of the insect, and a smart microcontroller based control system. The developed design is smart, environmentally safe, portable and highly cost effective yet very efficient in eliminating household pathogen-transmitting insects and pests Keywords: reverse aerodynamics, pest control, smart systems, insect trap, vacuum suction, mosquitoes.

Finite Element Analysis of Vertical and Horizontal Drainage Structures under Vacuum Combined Surcharge Preloading

Combined vacuum and surcharge preloading has gradually been widely used because of its advantages of low cost, green environmental protection, and good treatment effect. The conventional prefabricated vertical drain presents obvious defects in vacuum preloading treatment, such as obvious silting, serious bending of the drainage board, large attenuation of vacuum degree of drainage board along the depth, long construction period, and so on, which affect the final reinforcement effect. In this paper, the MIDAS finite element simulation of combined vacuum and surcharge preloading of prefabricated vertical drains (PVDs) and prefabricated horizontal drains (PHDs) is established through the comparative experiment of the engineering field. The comparative experimental study is carried out from the aspects of the vertical settlement, horizontal displacement, and pore water pressure. The results show that under combined vacuum and surcharge preloading, the consolidation effect of soft soil with PHDs is better than that with PVDs. When PHDs are used, the vertical settlement increases by 7.2% compared with PVDs; the horizontal displacement is larger; and the pore water pressure dissipates faster. This is because when the PHDs are adopted, the consolidation direction of the soil is consistent with the direction of the vacuum suction, which is mainly caused by vertical settlement. With the consolidation, the spacing between PHDs is gradually shortened, and the drainage distance is reduced, which can effectively reduce the consolidation time and improve the reinforcement effect of the soil. In addition, the PHDs can move downward uniformly with the soil during the consolidation process and have almost no bending deformation, which makes the vacuum transfer more uniform and effective.

Enhanced Non-Contact Grip Force and Swirl Stability by a Combined Venturi–Vortex Air Head

A combination of the venturi module and the vortex cup was proposed to solve vortex instability and to enhance grip capacity. Mounting a venturi suction pad inside the vortex cup improved vacuum generation efficiency. When the vortex cup properly maintained the non-contact air gap and generated an equivalent vacuum to achieve a sealing effect around the open gap of the suction pad, the combined head improved grip capacity and stabilized the non-contact environment. Furthermore, the flow patterns around the venturi chamber and the swirl inside the vortex cup were analyzed based on the design elements of each module. In a module that integrated some of the venturi’s features internally, increased air consumption of the vortex cup was required than that of the venturi. However, it supported a wide range of non-contact grips. The coupled model effectively protected the vacuum suction features of the venturi suction pad in all non-contact environments in that range.

Design and Implementation of a Low-Cost Microcontroller-Based an Industrial Delta Robot

This paper presents a practical design and control for a delta robot based on a low-cost microcontroller. The main purpose of the proposed delta robot is to improve and enhance industrial productivity such as fast pick-and-place tasks and fully autonomous production lines. Additionally, during a global pandemic similar to (COVID-19), some medical and food products suffer from a sudden increase and demand. Moreover, kinematics, workspace dynamics analysis took into consideration an optimized approach to achieve a viable yet efficient model representing them. Furthermore, stress analysis and material selection have been applied, targeting to achieve high customizability of the manipulator linages. Taking availability into considerations, most components are available locally for ease of manufacturing. To add a touch of machine vision to the robot, a camera module is mounted in an optimized fashion to optimize the robot's performance and increase its accuracy. Finally, various interchangeable end effectors can be mounted including a magnetic gripper, vacuum suction cup, soft-robotics grippers, and other types to suit our requirements and needs.

Influence of cerium content on the microstructure and thermal expansion properties of suction cast Al-Cu-Fe alloys

Low-expansion alloys are of great importance and can be used for the development of new aerospace materials. Herein, we report diverse rare earth quasicrystal alloys fabricated by the vacuum suction casting process. The effects of the addition of cerium (Ce) on the microstructure, thermal expansion properties and microhardness of the Al-Cu-Fe alloy were systematically investigated. This study discovered the tiny Al-Cu-Fe-Ce microstructure. A uniform distribution could be achieved after Ce addition amount is elevated. At the Ce addition amount of 1 at%, the lowest alloy thermal expansion coefficient was obtained. The alloy exhibited the maximum microhardness under these conditions. The microhardness of alloys containing 1 at% of Ce was approximately 2.4 times higher than the microhardness exhibited by alloys devoid of Ce additives. The coefficient of thermal expansion decreases by approximately 20%. The use of the suction casting process and the addition of an appropriate amount of Ce can potentially help design and develop Al-Cu-Fe-Ce alloys.

Design and simulation analysis of vacuum fish suction pump

Most of Chinese aquacultural products rely on artificial nets to catch in 2020. Fish suction pump can replace artificial net, is an important mechanical equipment of fish breeding industry. The development of fish suction pump is relatively backward and the level of automation is still to be improved, which is not conducive to the large-scale and rapid development of aquaculture in various countries. This paper designs a single tank vacuum suction fish pump, the suction fish pump mainly uses the tank and the air pressure difference, through the automatic control system on the suction fish pump and each stage of the control, relying on the gravity of the mixture of fish and water to release fish. In this paper, fluent was used to conduct simulation analysis on the flow diagram of fish-water mixture inhaled at work, and the flow diagram and velocity vector diagram of the internal flow field were obtained. The results show that the vacuum fish suction pump can effectively reduce the fish collision damage. The vacuum fish suction pump designed in this paper can effectively complete the fishing work of cultured fish, with the characteristics of high efficiency and low damage, which can provide theoretical reference for the design of vacuum fish suction pump in the future.

Role of SR vacuum cannula as novel technique for atonic PPH management study at Pannadhay Rajkiya Mahila Chikitsalaya and RNT Medical College, Udaipur

Background: Postpartum hemorrhage is a major obstetrical emergency and one of the important but preventable causes of maternal morbidity and mortality. It is often sudden, frequently unpredictable and catastrophic. In this study SR vacuum cannula will be applied to create negative pressure inside the uterine cavity with a specially designed uterine cannula, which is a simple, safe and cost-effective technique. The aim and objective of the study was to analyse the incidence, effectiveness of suction cannula in management of atonic PPH after failure of medical management over tamponade and the maternal outcome after suction technique.Methods: This observational study was conducted in Department of Obstetrics and Gynecology, RNT Medical College and Panna Dhay Rajkiya Mahila Chikitsalaya, Udaipur, Rajasthan. Patients requiring PPH management admitted to the obstetrics ward between August 2019 – December 2020. The Uterine Vacuum Retraction System consists of SR Suction cannula to control PPH after vaginal delivery. SR suction cannula for atonic PPH at caesarean delivery and High vacuum suction machine was used.Results: In majority of the patients bleeding was stopped within three minutes. 60 women (50%) bleeding was stopped within 3 minutes, in 38 women (31.7%) bleeding was stopped between 3-4 minutes and in 22 women (18.3%) bleeding was stopped >4 minutes. In 75 (62.5%) women negative pressure was applied only once, in 20 (16.7%) was applied two times and 25 women (20.8%) negative pressure was applied three times to stop bleeding. Blood collected in bottle after SR Cannula Application ranged from 100-150 ml.Conclusions: Vacuum suction cannulas should be made part and parcel of normal delivery tray to facilitate quick application. This simple and cost-effective technique takes very little time to organize and can stop bleeding within 3 minutes in atonic PPH as shown in this study.