Treatment of
cyclododecane-r-1,c-5,c-9-triyl tris(p-toluenesulphonate) with sodium azide in
dimethyl-formamide at 100� for 6 h gave the corresponding cis,cis-triazide
which upon hydrogenation or reduction with lithium aluminium hydride gave
cyclododecane-r-1,c-5,c-9-triamine, isolated as the tris-salicylidene
derivative. Acid hydrolysis of this, removal of the salicylaldehyde, and
treatment of the aqueous solution with sodium carbonate and
2,3-dimethoxybenzoyl chloride gave r-1,c-5,c- 9-tris(2,3-dimethoxybenzamido)cyclododecane.
��� Treatment of
(E,E,E)-cyclododeca-1,5,9-triene with an excess of acetonitrile and sulphuric
acid at room temperature for three days gave 18% of
(E,E)-1-acetamidocyclododeca-4,8-diene; no di- or
tri-amides were isolated.