Simultaneous voiding cystourethrography and voiding urosonography: Diagnostic comparison for vesicoureteral reflux

2003 ◽  
Vol 44 (3) ◽  
pp. 265-268
Author(s):  
M. Uhl ◽  
J. Kromeier ◽  
L.-B. Zimmerhackl ◽  
K. Darge

Purpose: To compare the diagnostic accuracy of contrast-enhanced voiding urosonography (VUS) and voiding cystourethrography (VCUG) during simultaneous performance of both examinations. Material and Methods: A total of 24 children, 16 girls and 8 boys, with a mean age of 3.5 years referred for reflux examination were recruited for the study. After transurethral bladder catheterization, radiographic contrast medium, followed directly by the US contrast medium, were administered. Fluoroscopic VCUG and VUS were carried out concurrently in the same patient. When 1 kidney was scanned by ultrasound, fluoroscopy was performed on the contralateral side. Results: In 19 of the 47 kidney-ureter-units (KUU) vesicoureteral reflux (VUR) was detected. In 16 units the reflux was detected by both VCUG and VUS. In 3 KUUs the reflux was detected only at VCUG. All 3 cases were grade 1. Taking the VCUG as the reference standard, VUS had 84% sensitivity, 100% specificity, 100% and 90% positive and negative predictive values, respectively. Conclusion: A dependable comparison could be achieved by performing VCUG and VUS at the same time and under the same conditions. It reconfirmed that VUS is reliable in the exclusion or verification of reflux.

2008 ◽  
Vol 136 (11-12) ◽  
pp. 617-620
Author(s):  
Milan Paunovic ◽  
Polina Pavicevic ◽  
Vladimir Radlovic ◽  
Vojkan Vukadinovic

INTRODUCTION Positional installation of contrast cystography (PIC cystography) represents a new method to identify vesicoureteral reflux (VUR) that is unrevealed by standard diagnostic procedures. It is performed by radiological examination of the vesicoureteral junction during cystoscopic installation of the contrast medium at the ureteral orifice. OBJECTIVE We studied the significance of PIC cystography to demonstrate VUR that failed to be revealed by standard voiding cystourethrography (MCUG), as well as the degree of the correlation of such a finding with endoscopic appearance and the position of the ureteral orifice (UO). METHOD The aim of the paper was to analyze a sample of 5 children (4 girls and 1 boy), aged 6-15 years (mean 9.8 years) with recurrent febrile urotract infections, complicated with scarring changes of the renal parenchyma and normal findings on MCUG. The grade of VUR demonstrated by PIC cystography was classified using the standard hydrodistensional scale. RESULTS All 5 patients had VUR, disclosed by PIC cystography, of whom in 4 it was unilateral and in one bilateral. Of 5 patients, 4 had VUR grade I and one grade II. All the children with VUR detected by PIC cystography also had evident cystoscopic abnormalities in the position and/or configuration of the ureteral orifice at the same side, while at the side with normal finding on PIC cystography, the endoscopic finding was also within normal limits. CONCLUSION PIC cystography is the method of choice in the confirmation of VUR as the cause of recurrent urotract infection and its complications in children with a normal finding on standard MCUG. In all our patients with VUR verified by PIC cystography, at the same side we also revealed endoscopic changes in the position and/or configuration of UO.


2015 ◽  
Vol 56 (6) ◽  
pp. 702-708 ◽  
Author(s):  
Karoline Meurer ◽  
Michael Laniado ◽  
Norbert Hosten ◽  
Bettina Kelsch ◽  
Barry Hogstrom

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Muhamad Idham Mohamed ◽  
Mohd Khairul Amran Mohammad ◽  
Hairil Rashmizal Abdul Razak ◽  
Khairunisak Abdul Razak ◽  
Wan Mazlina Md Saad

Emerging syntheses and findings of new metallic nanoparticles (MNPs) have become an important aspect in various fields including diagnostic imaging. To date, iodine has been utilized as a radiographic contrast medium. However, the raise concern of iodine threats on iodine-intolerance patient has led to search of new contrast media with lower toxic level. In this animal modeling study, 14 nm iron oxide nanoparticles (IONPs) with silane-polyethylene glycol (SiPEG) and perchloric acid have been assessed for toxicity level as compared to conventional iodine. The nanotoxicity of IONPs was evaluated in liver biochemistry, reactive oxygen species production (ROS), lipid peroxidation mechanism, and ultrastructural evaluation using transmission electron microscope (TEM). The hematological analysis and liver function test (LFT) revealed that most of the liver enzymes were significantly higher in iodine-administered group as compared to those in normal and IONPs groupsP<0.05. ROS production assay and lipid peroxidation indicator, malondialdehyde (MDA), also showed significant reductions in comparison with iodine groupP<0.05. TEM evaluation yielded the aberration of nucleus structure of iodine-administered group as compared to those in control and IONPs groups. This study has demonstrated the less toxic properties of IONPs and it may postulate that IONPs are safe to be applied as radiographic contrast medium.


1987 ◽  
Vol 28 (5) ◽  
pp. 601-602
Author(s):  
A. Alanen ◽  
P. Nummi ◽  
M. Kormano ◽  
K. Irjala

Relaxation times Tl of normal and abnormal urine samples were measured with a 0.02 tesla MRI device in a spectrometric mode. Protein containing urine from patients with glomerulonephritis showed a slight shortening of Tl relaxation time. Radiographic contrast medium, pH, osmolality or glucose in diabetes did not significantly change the Tl relaxation time of urine. Urine can be used as a T1 relaxation reference in MR imaging of the pelvis even if the patient has received radiographic contrast medium or has diabetes or proteinuria for any reason.


1991 ◽  
Vol 84 (1) ◽  
pp. 92-94 ◽  
Author(s):  
CONSTANCE A. JENNINGS ◽  
JOHN DEVEIKIS ◽  
NORIO AZUMI ◽  
HENRY YEAGER

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