Proton Tl Relaxation Time of Normal and Abnormal Urine

1987 ◽  
Vol 28 (5) ◽  
pp. 601-602
Author(s):  
A. Alanen ◽  
P. Nummi ◽  
M. Kormano ◽  
K. Irjala
Keyword(s):  
Relaxation Time ◽  
Mr Imaging ◽  
Contrast Medium ◽  
Relaxation Times ◽  
Urine Samples ◽  
Medium Ph ◽  
T1 Relaxation ◽  
Radiographic Contrast Medium ◽  
Radiographic Contrast

Relaxation times Tl of normal and abnormal urine samples were measured with a 0.02 tesla MRI device in a spectrometric mode. Protein containing urine from patients with glomerulonephritis showed a slight shortening of Tl relaxation time. Radiographic contrast medium, pH, osmolality or glucose in diabetes did not significantly change the Tl relaxation time of urine. Urine can be used as a T1 relaxation reference in MR imaging of the pelvis even if the patient has received radiographic contrast medium or has diabetes or proteinuria for any reason.

scholarly journals Intra-arterial and intravenous applications of Iosimenol 340 injection, a new non-ionic, dimeric, iso-osmolar radiographic contrast medium: phase 2 experience

2015 ◽  
Vol 56 (6) ◽  
pp. 702-708 ◽  
Author(s):  
Karoline Meurer ◽  
Michael Laniado ◽  
Norbert Hosten ◽  
Bettina Kelsch ◽  
Barry Hogstrom
Keyword(s):  
Contrast Medium ◽  
Phase 2 ◽  
Radiographic Contrast Medium ◽  
Radiographic Contrast

scholarly journals Nanotoxic Profiling of Novel Iron Oxide Nanoparticles Functionalized with Perchloric Acid and SiPEG as a Radiographic Contrast Medium

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Muhamad Idham Mohamed ◽  
Mohd Khairul Amran Mohammad ◽  
Hairil Rashmizal Abdul Razak ◽  
Khairunisak Abdul Razak ◽  
Wan Mazlina Md Saad
Keyword(s):  
Lipid Peroxidation ◽  
Iron Oxide ◽  
Contrast Medium ◽  
Iron Oxide Nanoparticles ◽  
Perchloric Acid ◽  
Metallic Nanoparticles ◽  
Oxide Nanoparticles ◽  
Radiographic Contrast Medium ◽  
Hematological Analysis ◽  
Radiographic Contrast

Emerging syntheses and findings of new metallic nanoparticles (MNPs) have become an important aspect in various fields including diagnostic imaging. To date, iodine has been utilized as a radiographic contrast medium. However, the raise concern of iodine threats on iodine-intolerance patient has led to search of new contrast media with lower toxic level. In this animal modeling study, 14 nm iron oxide nanoparticles (IONPs) with silane-polyethylene glycol (SiPEG) and perchloric acid have been assessed for toxicity level as compared to conventional iodine. The nanotoxicity of IONPs was evaluated in liver biochemistry, reactive oxygen species production (ROS), lipid peroxidation mechanism, and ultrastructural evaluation using transmission electron microscope (TEM). The hematological analysis and liver function test (LFT) revealed that most of the liver enzymes were significantly higher in iodine-administered group as compared to those in normal and IONPs groupsP<0.05. ROS production assay and lipid peroxidation indicator, malondialdehyde (MDA), also showed significant reductions in comparison with iodine groupP<0.05. TEM evaluation yielded the aberration of nucleus structure of iodine-administered group as compared to those in control and IONPs groups. This study has demonstrated the less toxic properties of IONPs and it may postulate that IONPs are safe to be applied as radiographic contrast medium.

Eosinophilic Pneumonia Associated With Reaction to Radiographic Contrast Medium

1991 ◽  
Vol 84 (1) ◽  
pp. 92-94 ◽  
Author(s):  
CONSTANCE A. JENNINGS ◽  
JOHN DEVEIKIS ◽  
NORIO AZUMI ◽  
HENRY YEAGER
Keyword(s):  
Contrast Medium ◽  
Eosinophilic Pneumonia ◽  
Radiographic Contrast Medium ◽  
Radiographic Contrast

Effect of cerebral angiography on subsequent brain scintigraphy

1974 ◽  
Vol 41 (6) ◽  
pp. 688-690
Author(s):  
Edward B. Silberstein ◽  
Alan B. Ashare
Keyword(s):  
Contrast Medium ◽  
Cerebral Angiography ◽  
Content Type ◽  
Radiographic Contrast Medium ◽  
Radiographic Contrast ◽  
Fine Print

✓ The authors report examination of 27 brain scintigraphs performed 1 day following cerebral angiography, and 48 performed within 2 weeks. No artifactual areas of uptake were produced in the scintigraphs by the radiographic contrast medium.

MTR and T1 provide complementary information in MS NAWM, but not in lesions

2000 ◽  
Vol 6 (5) ◽  
pp. 327-331 ◽  
Author(s):  
C M Griffin ◽  
G JM Parker ◽  
G J Barker ◽  
A J Thompson ◽  
D H Miller
Keyword(s):  
Relaxation Time ◽  
White Matter ◽  
Mixed Model ◽  
Relaxation Times ◽  
Tissue Type ◽  
Tissue Characterisation ◽  
Complementary Information ◽  
T1 Relaxation Time ◽  
T1 Relaxation ◽  
The Relationship

MTR and T1 relaxation times are abnormal in MS lesions and NAWM, and may reflect tissue damage such as demyelination and axonal loss. Their relationship and potential to provide complementary information in tissue characterisation is explored. The aim of this study was to document the relationship between magnetisation transfer ratio (MTR) and T1 relaxation time in Multiple Sclerosis (MS) lesions and normal appearing white matter (NAWM) in order to determine whether the combination provides a more comprehensive tissue characterisation than either parameter in isolation. Ten patients with relapsing remitting MS and 10 age matched healthy controls underwent imaging using a protocol which included the measurement of both MTR and T1 relaxation times. The MTR and T1 values were compared statistically using a commonly adopted correlation approach and a mixed-model regression approach. There was a strong correlation between MTR and T1 in MS lesions (r=0.74). The correlation was seen equally in T1 hypointense and isointense lesions. The relationship was much weaker in MS NAWM (r=0.24) and no correlation was found in control white matter (r=0.06). Mixed-model regression analysis confirmed that the relationship between T1 and MTR is strongly dependent upon tissue type (MS lesion, MS NAWM, or control white matter). The relationship between MTR and T1 relaxation time measurements varies markedly between pathological and normal tissue types. In MS, the complementary information obtained from MTR and T1 is most apparent in NAWM. The results emphasise the potential for combinations of MR parameters to improve tissue characterisation, which in turn should improve understanding of disease pathology and treatment monitoring.

Simultaneous voiding cystourethrography and voiding urosonography: Diagnostic comparison for vesicoureteral reflux

2003 ◽  
Vol 44 (3) ◽  
pp. 265-268
Author(s):  
M. Uhl ◽  
J. Kromeier ◽  
L.-B. Zimmerhackl ◽  
K. Darge
Keyword(s):  
Contrast Medium ◽  
Vesicoureteral Reflux ◽  
Contralateral Side ◽  
Voiding Cystourethrography ◽  
Voiding Urosonography ◽  
Predictive Values ◽  
Contrast Enhanced ◽  
Radiographic Contrast Medium ◽  
The Us ◽  
Radiographic Contrast

Purpose: To compare the diagnostic accuracy of contrast-enhanced voiding urosonography (VUS) and voiding cystourethrography (VCUG) during simultaneous performance of both examinations. Material and Methods: A total of 24 children, 16 girls and 8 boys, with a mean age of 3.5 years referred for reflux examination were recruited for the study. After transurethral bladder catheterization, radiographic contrast medium, followed directly by the US contrast medium, were administered. Fluoroscopic VCUG and VUS were carried out concurrently in the same patient. When 1 kidney was scanned by ultrasound, fluoroscopy was performed on the contralateral side. Results: In 19 of the 47 kidney-ureter-units (KUU) vesicoureteral reflux (VUR) was detected. In 16 units the reflux was detected by both VCUG and VUS. In 3 KUUs the reflux was detected only at VCUG. All 3 cases were grade 1. Taking the VCUG as the reference standard, VUS had 84% sensitivity, 100% specificity, 100% and 90% positive and negative predictive values, respectively. Conclusion: A dependable comparison could be achieved by performing VCUG and VUS at the same time and under the same conditions. It reconfirmed that VUS is reliable in the exclusion or verification of reflux.

Kinin Activation as a Predictive Assay for Adverse Reactions to Radiographic Contrast Medium

1984 ◽  
Vol 25 (4) ◽  
pp. 337-342 ◽  
Author(s):  
D. H. Carr ◽  
A. C. Walker
Keyword(s):  
Contrast Medium ◽  
Conversion Rate ◽  
Adverse Reactions ◽  
Factor Xii ◽  
C1 Esterase Inhibitor ◽  
Radiographic Contrast Medium ◽  
Radiographic Contrast ◽  
Predictive Assay ◽  
Esterase Inhibitor

The rate of conversion in vitro, of prekallikrein to kallikrein has been measured in 74 reactors to contrast medium and 70 controls. The conversion rate is significantly more rapid in reactors than controls. There was no difference in C1-esterase inhibitor and factor XII levels between reactors and controls. This retrospective investigation suggests that prekallikrein/kallikrein conversion rate may form the basis of a test for differentiating between reactors and non-reactors.

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