Power of Experimental Design Studies for the Validation of Pharmaceutical Processes: Case Study of a Multilayer Tablet Manufacturing Process

2002 ◽  
Vol 28 (7) ◽  
pp. 841-848 ◽  
Author(s):  
F. Goutte ◽  
F. Guemguem ◽  
C. Dragan ◽  
G. Vergnault ◽  
P. Wehrlé
2019 ◽  
Vol 354 ◽  
pp. 199-210 ◽  
Author(s):  
S.C. Galbraith ◽  
B. Cha ◽  
Z. Huang ◽  
S. Park ◽  
H. Liu ◽  
...  

2012 ◽  
Vol 232 ◽  
pp. 823-827
Author(s):  
Frederic Danesi ◽  
Nicolas Gardan ◽  
Elvis Kwassi

This article focuses on the optimization of a design process, in the context of automotive subcontracting opportunity. This optimization is guided by the underlying manufacturing process and by the industrial knowledge. We first show that the actual design studies are biased by the final goal (a formal design) and do not take into account early industrial needs (a draft design to draw up an estimate). We then demonstrate how an automaker subcontractor optimizes the early design process thanks to industrial knowledge.


2011 ◽  
Vol 20 (4) ◽  
pp. 109-113
Author(s):  
Karen Copple ◽  
Rajinder Koul ◽  
Devender Banda ◽  
Ellen Frye

Abstract One of the instructional techniques reported in the literature to teach communication skills to persons with autism is video modeling (VM). VM is a form of observational learning that involves watching and imitating the desired target behavior(s) exhibited by the person on the videotape. VM has been used to teach a variety of social and communicative behaviors to persons with developmental disabilities such as autism. In this paper, we describe the VM technique and summarize the results of two single-subject experimental design studies that investigated the acquisition of spontaneous requesting skills using a speech generating device (SGD) by persons with autism following a VM intervention. The results of these two studies indicate that a VM treatment package that includes a SGD as one of its components can be effective in facilitating communication in individuals with autism who have little or no functional speech.


2021 ◽  
Vol 8 (1) ◽  
pp. 1896419
Author(s):  
Muhammad Hamad Sajjad ◽  
Khawar Naeem ◽  
Muhammad Zubair ◽  
Qazi Muhammad Usman Jan ◽  
Sikandar Bilal Khattak ◽  
...  

Author(s):  
R. Ascione ◽  
W. Polini ◽  
Q. Semeraro

Many well-known approaches exist in the literature for tolerance analysis. All the methods proposed in the literature consider the dimensional and the geometric tolerances applied to some critical points (contact points among profiles belonging to couples of parts) on the surface of the assembly components. These points are generally considered uncorrelated since the nominal surface is considered. Therefore, the methods proposed in the literature do not consider the actual surface due to a manufacturing process. Every manufacturing process leaves on the surface a signature, i.e., a systematic pattern that characterizes all the features machined with that process. The aim of the present work is to investigate the effects of considering the manufacturing signature in solving a tolerance stack-up function. A case study involving three parts has been defined and solved by means of a method of the literature, the variational method, with and without considering the correlation among the points of the same surface due to the manufacturing signature. This work represents a first step toward the integration of the design and the manufacturing in a concurrent engineering approach.


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