Stimuli-Responsive Materials: Thermo- and pH-Responsive Polymers for Drug Delivery

2016 ◽  
pp. 7635-7655 ◽  
Author(s):  
Jasbir Singh ◽  
Harmeet Kaur
Keyword(s):  
Drug Delivery ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Responsive Materials ◽  
Responsive Polymers ◽  
Ph Responsive Polymers

scholarly journals Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery

2020 ◽  
Vol 21 (13) ◽  
pp. 4724 ◽  
Author(s):  
Sofia Municoy ◽  
María I. Álvarez Echazú ◽  
Pablo E. Antezana ◽  
Juan M. Galdopórpora ◽  
Christian Olivetti ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Smart Materials ◽  
Controlled Drug Release ◽  
Stimuli Responsive ◽  
Responsive Materials ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Stimuli Response ◽  
Materials Used

Smart or stimuli-responsive materials are an emerging class of materials used for tissue engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state, light, and magnet fields) are being investigated for their potential to change a material’s properties, interactions, structure, and/or dimensions. The specificity of stimuli response, and ability to respond to endogenous cues inherently present in living systems provide possibilities to develop novel tissue engineering and drug delivery strategies (for example materials composed of stimuli responsive polymers that self-assemble or undergo phase transitions or morphology transformations). Herein, smart materials as controlled drug release vehicles for tissue engineering are described, highlighting their potential for the delivery of precise quantities of drugs at specific locations and times promoting the controlled repair or remodeling of tissues.

scholarly journals Review of Stimuli-Responsive Polymers in Drug Delivery and Textile Application

Molecules ◽  
2019 ◽  
Vol 24 (14) ◽  
pp. 2547 ◽  
Author(s):  
Sudipta CHATTERJEE ◽  
Patrick Chi-leung HUI
Keyword(s):  
Drug Delivery ◽  
Pluronic F127 ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Natural Polymers ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
General Drug ◽  
Different Temperatures ◽  
Synthetic Origin

This review describes some commercially available stimuli-responsive polymers of natural and synthetic origin, and their applications in drug delivery and textiles. The polymers of natural origin such as chitosan, cellulose, albumin, and gelatin are found to show both thermo-responsive and pH-responsive properties and these features of the biopolymers impart sensitivity to act differently under different temperatures and pH conditions. The stimuli-responsive characters of these natural polymers have been discussed in the review, and their respective applications in drug delivery and textile especially for textile-based transdermal therapy have been emphasized. Some practically important thermo-responsive polymers such as pluronic F127 (PF127) and poly(N-isopropylacrylamide) (pNIPAAm) of synthetic origin have been discussed in the review and they are of great importance commercially because of their in situ gel formation capacity. Some pH-responsive synthetic polymers have been discussed depending on their surface charge, and their drug delivery and textile applications have been discussed in this review. The selected stimuli-responsive polymers of synthetic origin are commercially available. Above all, the applications of bio-based or synthetic stimuli-responsive polymers in textile-based transdermal therapy are given special regard apart from their general drug delivery applications. A special insight has been given for stimuli-responsive hydrogel drug delivery systems for textile-based transdermal therapy, which is critical for the treatment of skin disease atopic dermatitis.

PH Responsive Polymers in Drug Delivery

2018 ◽  
Vol 11 (11) ◽  
pp. 5115
Author(s):  
Muhammad Fathiy Mutalabisin ◽  
Bappaditya Chatterjee ◽  
Juliana Md. Jaffri
Keyword(s):  
Drug Delivery ◽  
Ph Responsive ◽  
Responsive Polymers ◽  
Ph Responsive Polymers

Revisiting structure-property relationship of pH-responsive polymers for drug delivery applications

2017 ◽  
Vol 253 ◽  
pp. 46-63 ◽  
Author(s):  
Salime Bazban-Shotorbani ◽  
Mohammad Mahdi Hasani-Sadrabadi ◽  
Akbar Karkhaneh ◽  
Vahid Serpooshan ◽  
Karl I Jacob ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Structure Property ◽  
Ph Responsive ◽  
Responsive Polymers ◽  
Property Relationship ◽  
Structure Property Relationship ◽  
Drug Delivery Applications ◽  
Ph Responsive Polymers ◽  
Relationship Of
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