PREPARATION AND CHARACTERIZATION OF POLYLACTIDE-POLY(ETHYLENE GLYCOL)-POLYLACTIDE TRIBLOCK POLYMERS AND A PRELIMINARYIN VIVOEXAMINATION OF THE BLOOD CIRCULATION TIME FOR THE NANOPARTICLES MADE THEREFROM

1999 ◽  
Vol 36 (12) ◽  
pp. 1863-1877 ◽  
Author(s):  
Kazuo Sakurai ◽  
Yuichiro Nakada ◽  
Tomomi Nakamura ◽  
Reiko Tudomi ◽  
Junko Matumoto ◽  
...  
2005 ◽  
Vol 288-289 ◽  
pp. 163-166 ◽  
Author(s):  
You Rong Duan ◽  
W.S. Liu ◽  
J. Liu ◽  
Z.R. Zhang

The objective of this study was to evaluate the in vivo characteristics of poly (ethylene glycol)-poly (lacticacid-co-glycolicacid)-poly (ethylene- glycol) (PELGE) copolymers as drug carriers. In order to test this circulation time, mitoxantrone (DHAQ) was used as a model drug in this study. DHAQ nanoparticles (DHAQ-NP) were prepared, subsequently the DHAQ-NP were evaluated by measuring the drug concentration in plasma after intravenous administration via the tail vein of mice. The circulation time of the DHAQ-NP were tested. The results showed prolonged mitoxantrone (DHAQ) residence in systemic blood circulation.


RSC Advances ◽  
2017 ◽  
Vol 7 (86) ◽  
pp. 54603-54609 ◽  
Author(s):  
Changqiang Wu ◽  
Li Yang ◽  
Zhuzhong Chen ◽  
Houbing Zhang ◽  
Danyang Li ◽  
...  

PEGylated Mn2+ complexes show higher relaxivity and longer blood circulation time than free Mn2+ complexes.


2013 ◽  
Vol 27 (2) ◽  
pp. 216-226 ◽  
Author(s):  
Md. Kamal Khan ◽  
Mohammed Mizanur Rahman ◽  
Bodrun Nesa ◽  
Romana Nasrin ◽  
Swajal Molla ◽  
...  

RSC Advances ◽  
2015 ◽  
Vol 5 (46) ◽  
pp. 36715-36726 ◽  
Author(s):  
Bakhshali Massoumi ◽  
Somayeh Davtalab ◽  
Mehdi Jaymand ◽  
Ali Akbar Entezami

The aim of this study is the synthesis, and characterization of novel type AB2 Y-shaped miktoarm star conductive polyaniline-modified poly(ethylene glycol), and preparation of its electrospun nanofibers blend with poly(ε-caprolactone).


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