Structural heterogeneity of the C3b/C4b receptor (Cr 1) on human peripheral blood cells.
1983 ◽
Vol 157
(6)
◽
pp. 2160-2165
◽
Keyword(s):
In these studies CR 1 polymorphism previously demonstrated on erythrocytes (E) was also found on CR 1-bearing peripheral blood leukocytes including polymorphonuclear (PMN), eosinophils, monocytes, and B lymphocytes. However several cell-specific differences in CR1 were found: (a) an approximately 5,000-dalton increase in CR 1 on PMN and eosinophils, (b) unequal band intensity among heterozygotes suggests that there is preferential expression of 220,000- or 225,000-dalton receptors on leukocytes compared to E, and (c) "minor" bands, approximately 15,000 daltons larger than the major receptor molecule, were found on E but not on leukocytes. These observations constitute a unique example of heterogeneity of an integral membrane receptor.
1979 ◽
Vol 91
(9-10)
◽
pp. 1117-1125
Keyword(s):
1979 ◽
Vol 91
(9-10)
◽
pp. 1101-1115
1996 ◽
Vol 51
(7-8)
◽
pp. 493-499
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1982 ◽
Vol 109
(2)
◽
pp. 363-369
◽
1992 ◽
Vol 267
(10)
◽
pp. 6886-6892
◽
Keyword(s):
Keyword(s):