scholarly journals Estimation and Testing of Parent-of-Origin Effects for Quantitative Traits

2003 ◽  
Vol 72 (4) ◽  
pp. 1035-1039 ◽  
Author(s):  
John C. Whittaker ◽  
Neda Gharani ◽  
Peter Hindmarsh ◽  
Mark I. McCarthy
Keyword(s):  
Quantitative Traits ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Detection of Parent-of-Origin Effects for Quantitative Traits in Complete and Incomplete Nuclear Families With Multiple Children

2011 ◽  
Vol 174 (2) ◽  
pp. 226-233 ◽  
Author(s):  
Feng He ◽  
Ji-Yuan Zhou ◽  
Yue-Qing Hu ◽  
Fengzhu Sun ◽  
Jingyuan Yang ◽  
...  
Keyword(s):  
Quantitative Traits ◽  
Nuclear Families ◽  
Parent Of Origin ◽  
Origin Effects

Detection of parent-of-origin effects for quantitative traits using general pedigree data

2014 ◽  
Vol 93 (2) ◽  
pp. 339-347 ◽  
Author(s):  
HAI-QIANG HE ◽  
WEI-GAO MAO ◽  
DONGDONG PAN ◽  
JI-YUAN ZHOU ◽  
PING-YAN CHEN ◽  
...  
Keyword(s):  
Quantitative Traits ◽  
Pedigree Data ◽  
General Pedigree ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Assessment of Parent-of-Origin Effects in Linkage Analysis of Quantitative Traits

2001 ◽  
Vol 68 (4) ◽  
pp. 951-962 ◽  
Author(s):  
Robert L. Hanson ◽  
Sayuko Kobes ◽  
Robert S. Lindsay ◽  
William C. Knowler
Keyword(s):  
Linkage Analysis ◽  
Quantitative Traits ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals A Powerful Test of Parent-of-Origin Effects for Quantitative Traits Using Haplotypes

PLoS ONE ◽  
2011 ◽  
Vol 6 (12) ◽  
pp. e28909 ◽  
Author(s):  
Rui Feng ◽  
Yinghua Wu ◽  
Gun Ho Jang ◽  
Jose M. Ordovas ◽  
Donna Arnett
Keyword(s):  
Quantitative Traits ◽  
Powerful Test ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals A powerful genome-wide feasible approach to detect parent-of-origin effects in studies of quantitative traits

2009 ◽  
Vol 18 (3) ◽  
pp. 379-384 ◽  
Author(s):  
Nadezhda M Belonogova ◽  
Tatiana I Axenovich ◽  
Yurii S Aulchenko
Keyword(s):  
Quantitative Traits ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Correction: A Powerful Test of Parent-of-Origin Effects for Quantitative Traits Using Haplotypes

PLoS ONE ◽  
2012 ◽  
Vol 7 (7) ◽  
Author(s):  
Rui Feng ◽  
Yinghua Wu ◽  
Gun Ho Jang ◽  
Jose M. Ordovas ◽  
Donna Arnett
Keyword(s):  
Quantitative Traits ◽  
Powerful Test ◽  
Parent Of Origin ◽  
Origin Effects

Analysis of parent of origin effects in Sorbs using long range phasing algorithms

2014 ◽  
Vol 9 (S 01) ◽  
Author(s):  
X Liu ◽  
M Scholz ◽  
A Tönjes ◽  
M Stumvoll ◽  
PF Stadler ◽  
...  
Keyword(s):  
Long Range ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Parent-of-origin effects on voluntary exercise levels and body composition in mice

2010 ◽  
Vol 40 (2) ◽  
pp. 111-120 ◽  
Author(s):  
Scott A. Kelly ◽  
Derrick L. Nehrenberg ◽  
Kunjie Hua ◽  
Ryan R. Gordon ◽  
Theodore Garland ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Fat ◽  
Wheel Running ◽  
Voluntary Exercise ◽  
Phenotypic Variance ◽  
In Utero Environment ◽  
Dependent Activity ◽  
Health Related ◽  
Parent Of Origin ◽  
Origin Effects

Despite the health-related benefits of exercise, many people do not engage in enough activity to realize the rewards, and little is known regarding the genetic or environmental components that account for this individual variation. We created and phenotyped a large G4 advanced intercross line originating from reciprocal crosses between mice with genetic propensity for increased voluntary exercise (HR line) and the inbred strain C57BL/6J. G4 females (compared to males) ran significantly more when provided access to a running wheel and were smaller with a greater percentage of body fat pre- and postwheel access. Change in body composition resulting from a 6-day exposure to wheels varied between the sexes with females generally regulating energy balance more precisely in the presence of exercise. We observed parent-of-origin effects on most voluntary wheel running and body composition traits, which accounted for 3–13% of the total phenotypic variance pooled across sexes. G4 individuals descended from progenitor (F0) crosses of HR♀ and C57BL/6J♂ ran greater distances, spent more time running, ran at higher maximum speeds/day, and had lower percent body fat and higher percent lean mass than mice descended from reciprocal progenitor crosses (C57BL/6J♀ × HR♂). For some traits, significant interactions between parent of origin and sex were observed. We discuss these results in the context of sex dependent activity and weight loss patterns, the contribution of parent-of-origin effects to predisposition for voluntary exercise, and the genetic (i.e., X-linked or mtDNA variations), epigenetic (i.e., genomic imprinting), and environmental (i.e., in utero environment or maternal care) phenomena potentially modulating these effects.

scholarly journals Mutations in the FIE and MEA Genes That Encode Interacting Polycomb Proteins Cause Parent-of-Origin Effects on Seed Development by Distinct Mechanisms

2000 ◽  
Vol 12 (12) ◽  
pp. 2367-2381 ◽  
Author(s):  
Ramin Yadegari ◽  
Tetsu Kinoshita ◽  
Ofra Lotan ◽  
Gal Cohen ◽  
Anat Katz ◽  
...  
Keyword(s):  
Seed Development ◽  
Polycomb Proteins ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Genome-Wide Linkage Analysis Assessing Parent-of-Origin Effects in the Inheritance of Type 2 Diabetes and BMI in Pima Indians

Diabetes ◽  
2001 ◽  
Vol 50 (12) ◽  
pp. 2850-2857 ◽  
Author(s):  
R. S. Lindsay ◽  
S. Kobes ◽  
W. C. Knowler ◽  
P. H. Bennett ◽  
R. L. Hanson
Keyword(s):  
Type 2 Diabetes ◽  
Linkage Analysis ◽  
Pima Indians ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects
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