scholarly journals Parent-of-origin effects on voluntary exercise levels and body composition in mice

2010 ◽  
Vol 40 (2) ◽  
pp. 111-120 ◽  
Author(s):  
Scott A. Kelly ◽  
Derrick L. Nehrenberg ◽  
Kunjie Hua ◽  
Ryan R. Gordon ◽  
Theodore Garland ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Fat ◽  
Wheel Running ◽  
Voluntary Exercise ◽  
Phenotypic Variance ◽  
In Utero Environment ◽  
Dependent Activity ◽  
Health Related ◽  
Parent Of Origin ◽  
Origin Effects

Despite the health-related benefits of exercise, many people do not engage in enough activity to realize the rewards, and little is known regarding the genetic or environmental components that account for this individual variation. We created and phenotyped a large G4 advanced intercross line originating from reciprocal crosses between mice with genetic propensity for increased voluntary exercise (HR line) and the inbred strain C57BL/6J. G4 females (compared to males) ran significantly more when provided access to a running wheel and were smaller with a greater percentage of body fat pre- and postwheel access. Change in body composition resulting from a 6-day exposure to wheels varied between the sexes with females generally regulating energy balance more precisely in the presence of exercise. We observed parent-of-origin effects on most voluntary wheel running and body composition traits, which accounted for 3–13% of the total phenotypic variance pooled across sexes. G4 individuals descended from progenitor (F0) crosses of HR♀ and C57BL/6J♂ ran greater distances, spent more time running, ran at higher maximum speeds/day, and had lower percent body fat and higher percent lean mass than mice descended from reciprocal progenitor crosses (C57BL/6J♀ × HR♂). For some traits, significant interactions between parent of origin and sex were observed. We discuss these results in the context of sex dependent activity and weight loss patterns, the contribution of parent-of-origin effects to predisposition for voluntary exercise, and the genetic (i.e., X-linked or mtDNA variations), epigenetic (i.e., genomic imprinting), and environmental (i.e., in utero environment or maternal care) phenomena potentially modulating these effects.

scholarly journals Genome-wide random regression analysis for parent-of-origin effects of body composition allometries in mouse

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Jingli Zhao ◽  
Shuling Li ◽  
Lijuan Wang ◽  
Li Jiang ◽  
Runqing Yang ◽  
...  
Keyword(s):  
Body Composition ◽  
Regression Analysis ◽  
Random Regression ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Body Composition of Children in the Pre-pubertal and Early-pubertal Period: Are There Some Age-related and Intersexual Differences?

GYMNASIUM ◽  
2019 ◽  
Vol XIX (2) ◽  
pp. 64
Author(s):  
Pavol Čech ◽  
Pavel Ružbarský ◽  
Ľubomír Paučír ◽  
Dalibor Dzugas
Keyword(s):  
Body Composition ◽  
Body Fat ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
Age Related ◽  
Health Related ◽  
Wallis Anova ◽  
Vega 1

The aim of the presented study was to assess changes in body composition and intersexual differences among children at pre-pubertal and early-pubertal age. The research was designed as a non-randomized cross-section study. The screened sample consisted of 136 girls and 212 boys assigned into three groups according to their age. Body composition was measured using a direct segmental multi-frequency bioelectrical impedance analysis (DSM-BIA). To examine the association between obesity and selected health-related parameters, Kruskal-Wallis ANOVA and Eta2 were used. For evaluation of intersexual differences, Mann-Whitney U-test was used. The presented article is the part of VEGA 1/0840/17 project. From the perspective of age, neither in the group of girls nor boys we recorded any differences in indicators of body composition, namely in body fat mass index, body fat percentage and, in addition, in the group of girls in the waist to hip ratio parameter.

Wheel running of kangaroo rats, Dipodomys merriami, as related to food deprivation and body composition

1978 ◽  
Vol 44 (1) ◽  
pp. 17-20 ◽  
Author(s):  
D. B. Dill ◽  
L. F. Soholt ◽  
J. D. Morris
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Body Weight ◽  
Food Deprivation ◽  
Body Fat ◽  
Wheel Running ◽  
Initial Amount ◽  
Kangaroo Rats ◽  
Dipodomys Merriami ◽  
Percentage Of Body Fat

Kangaroo rats deprived of food ran themselves to death in 48 h in wheel cages. Despite the loss of 14.5% of body weight the ratio of water to protein was the same after the run as it was in control rats. Metabolic measurements at rest and in the running wheel and weight loss in the 48-h run were used to estimate fuels used and water expended. Two-thirds of the initial amount of fat and 9% of the protein were metabolized. The terminal mean percentage of body fat was about twice that observed in rats trapped in the spring of 1967, when seed production was low: death in the 48-h run could not have been due to depletion of body fat alone. The powerful activity drive seen in hungary kangaroo rats presumably is intensified in dry years when food is scarce and may deplete their reserves enough to result in death from starvation.

scholarly journals Nutrition and body composition of elite rhythmic gymnasts from Bulgaria

2019 ◽  
Vol 15 (1) ◽  
pp. 108-116 ◽  
Author(s):  
Silvia Miteva ◽  
Iliya Yanev ◽  
Stefan Kolimechkov ◽  
Lubomir Petrov ◽  
Lubomir Mladenov ◽  
...  
Keyword(s):  
Body Composition ◽  
Muscle Mass ◽  
Body Fat ◽  
Nutrient Intake ◽  
The Body ◽  
Ideal Weight ◽  
National Team ◽  
Health Related ◽  
Female Gymnasts ◽  
Rhythmic Gymnasts

Rhythmic gymnastics is a sport in which special consideration is given to diet and body appearance. The purpose of this study was to assess the nutrient intake and body composition of elite rhythmic gymnasts in comparison with guidelines for female gymnasts. Twenty-one elite rhythmic gymnasts from Bulgaria were divided into three groups: First National Team, mean age 24.2; Second National Team, mean age 17.8; and Junior National Team, mean age 12.6. Body fat and muscle mass were estimated by skinfold methods, and a food frequency questionnaire was applied to assess the nutrient intake. The gymnasts showed low per cent of body fat (13.9% for the First National Team, 17.0% for the Second National Team, and 15.6% for the Junior National Team) and high per cent muscle mass (44.0, 40.5, and 37.6%, respectively). They kept their weight close to the ideal one, as recommended by the coaches, and the following equation best corresponded to the recommended ideal weight: height (cm) − 118. The energy intake was lower than the calculated energy requirements, in addition to low intake of fat and carbohydrates. The relative protein intake was 1.7 g/kg for the First National Team, 1.7 g/kg for the Second National Team, and 1.9 g/kg for Junior National Team, and the energy contribution of proteins was higher than the recommended 15%. Rhythmic gymnasts should be encouraged to maintain their ideal weight without great variance from the health-related guidelines, and coaches should consider not only the body image, but also the norms relating to body composition in women when determining ideal weight.

scholarly journals Partitioning Phenotypic Variance Due to Parent-of-Origin Effects Using Genomic Relatedness Matrices

2017 ◽  
Vol 48 (1) ◽  
pp. 67-79 ◽  
Author(s):  
Charles Laurin ◽  
Gabriel Cuellar-Partida ◽  
Gibran Hemani ◽  
George Davey Smith ◽  
Jian Yang ◽  
...  
Keyword(s):  
Phenotypic Variance ◽  
Parent Of Origin ◽  
Origin Effects ◽  
Genomic Relatedness

scholarly journals Fitness knowledge, cardiorespiratory endurance and body composition of high school students

2013 ◽  
Vol 5 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Skip M. Williams ◽  
Dan Phelps ◽  
Kelly R. Laurson ◽  
David Q. Thomas ◽  
Dale D. Brown
Keyword(s):  
High School ◽  
Body Composition ◽  
High School Students ◽  
Body Fat ◽  
Aerobic Capacity ◽  
Percent Body Fat ◽  
School Students ◽  
Health Related ◽  
Exam Scores ◽  
Health Related Fitness

Summary Study aim: The purpose of this study was to determine if high school physical education seniors’ health-related fitness knowledge is related to their aerobic capacity and body composition. Material and methods: The FitSmart test assessed students (n = 171) health-related fitness knowledge. Aerobic capacity was calculated based on the students PACER score. Body Composition was measured using the Tanita TBF 300A body composition analyzer. Results: Aerobic fitness was a statistically significant predictor of exam score (β = 0.563, p < 0.001), but percent body fat was not (β = 0.185, p =0.074). Comparing the health-related fitness exam scores by the FITNESSGRAM classification system, students who were classified as Very Lean and High Risk for body composition had lower exam scores than those classified in the healthy fitness zone. Conclusions: The results confirmed previous findings that students have inadequate health-related fitness knowledge. Furthermore, the study extends these findings by identifying some associations of percent body fat and estimated VO2max to health-related fitness knowledge.

scholarly journals Partitioning phenotypic variance due to parent-of-origin effects using genomic relatedness matrices

2017 ◽  
Author(s):  
Charles Laurin ◽  
Gabriel Cuellar Partida ◽  
Gibran Hemani ◽  
George Davey Smith ◽  
Jian Yang ◽  
...  
Keyword(s):  
Phenotypic Variance ◽  
Parent Of Origin ◽  
Origin Effects ◽  
Genomic Relatedness

Reaction of University Students to Body Composition Assessment in Physical Education Activity Classes

1991 ◽  
Vol 10 (3) ◽  
pp. 249-260 ◽  
Author(s):  
Mary A. Steinhardt ◽  
Debra J. Macklem
Keyword(s):  
Body Composition ◽  
Physical Education ◽  
Body Fat ◽  
Psychological Impact ◽  
The Body ◽  
Body Composition Assessment ◽  
Technical Accuracy ◽  
Health Related ◽  
Skinfold Measurements ◽  
Education Activity

The use of skinfold measurements is a popular method to determine percentage of body fat because of its relative simplicity. Although attention has been paid to its technical accuracy and validity, less consideration has been given to the psychological impact on participants. The purpose of this study was to determine students’ (N = 128) reactions to having skinfold measurements taken in university physical education classes. Skinfold measurements were taken, and a questionnaire administered during the 2nd and 13th weeks of the semester. The questionnaire was used to assess (a) if students were self-conscious or uncomfortable during the measurements, (b) if knowing percent body fat motivated students to exercise, and (c) if the procedure should remain a standard part of class. Descriptive results indicated most students agreed that percent fat measurement was a valuable part of the class. On the pretest, after controlling for sex, regression analysis revealed that percent fat significantly predicted feelings of self-consciousness (R2 =.08; β = .36) and motivation to exercise (R2 = .07; β.24). On the posttest, percent fat again predicted feelings of self-consciousness (R2 = .21; β = .58) but did not predict motivation to exercise. Also, students with greater percent fat felt the body composition assessment should be optional (R2 = .08; β = −.36). Although results of this study support body composition assessment in university health-related activity classes, the need for sensitivity to the emotional needs and privacy of individuals is recommended.

scholarly journals Quantitative genomics of voluntary exercise in mice: transcriptional analysis and mapping of expression QTL in muscle

2014 ◽  
Vol 46 (16) ◽  
pp. 593-601 ◽  
Author(s):  
Scott A. Kelly ◽  
Derrick L. Nehrenberg ◽  
Kunjie Hua ◽  
Theodore Garland ◽  
Daniel Pomp
Keyword(s):  
Body Composition ◽  
Candidate Genes ◽  
Wheel Running ◽  
Expression Profiles ◽  
Voluntary Exercise ◽  
Transcriptional Analysis ◽  
Expression Qtl ◽  
Cis Acting ◽  
Intensity Of Exercise ◽  
The Brain

Motivation and ability both underlie voluntary exercise, each with a potentially unique genetic architecture. Muscle structure and function are one of many morphological and physiological systems acting to simultaneously determine exercise ability. We generated a large ( n = 815) advanced intercross line of mice (G4) derived from a line selectively bred for increased wheel running (high runner) and the C57BL/6J inbred strain. We previously mapped quantitative trait loci (QTL) contributing to voluntary exercise, body composition, and changes in body composition as a result of exercise. Using brain tissue in a subset of the G4 ( n = 244), we have also previously reported expression QTL (eQTL) colocalizing with the QTL for the higher-level phenotypes. Here, we examined the transcriptional landscape of hind limb muscle tissue via global mRNA expression profiles. Correlations revealed an ∼1,168% increase in significant relationships between muscle transcript expression levels and the same exercise and body composition phenotypes examined previously in the brain. The exercise trait most often significantly correlated with gene expression in the brain was running duration while in the muscle it was maximum running speed. This difference may indicate that time spent engaging in exercise behavior may be more influenced by central (neurobiological) mechanisms, while intensity of exercise may be largely controlled by peripheral mechanisms. Additionally, we used subsets of cis-acting eQTL, colocalizing with QTL, to identify candidate genes based on both positional and functional evidence. We discuss three plausible candidate genes ( Insig2, Prcp, Sparc) and their potential regulatory role.

Estimates of variances due to parent of origin effects for weights of Australian beef cattle

2012 ◽  
Vol 52 (4) ◽  
pp. 215 ◽  
Author(s):  
Karin Meyer ◽  
Bruce Tier
Keyword(s):  
Animal Model ◽  
Large Scale ◽  
Relationship Matrix ◽  
Phenotypic Variance ◽  
Maternal Parent ◽  
Hereford Cattle ◽  
Paternal Parent ◽  
Parent Of Origin ◽  
Origin Effects ◽  
Set Up

Estimates of variances due to differential expression of paternally and maternally derived genes can be obtained from animal model type analyses by fitting appropriate gametic effects. This is feasible for large-scale analyses, because the inverse of the gametic relationship matrix can be set up directly from a list of pedigrees. We present a series of analyses applying such a model to large sets of records for birth, weaning, yearling and final weights of Australian Angus and Hereford cattle. On one hand, results show that maternal genetic effects on these traits are largely confounded with maternal parent of origin effects, so that it is difficult to reliably separate the respective variance components. On the other hand, paternal parent of origin effects tend to act similarly to sire × herd effects so that estimates of their variance are inflated by any effects not modelled and contributing to such apparent interaction. Fitting an animal model with both parent of offspring effects, maternal genetic and permanent environmental effects as well as sire × herd and maternal grand-sire × herd of origin of dam interactions as additional random effects yielded estimates of the variance due to paternal parent of origin effects of 5–7% of the phenotypic variation for birth and weaning weights and of 0–1% for yearling and final weights. Corresponding estimates for maternal parent of origin effects were 0–11% for birth and weaning weights and 7–8% for yearling and final weights, while sire and maternal grand-sire interaction effects explained from 0 to 4% of the phenotypic variance.

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