Assessment of S-phase coated medical grade stainless steel (Ortron 90) for use in the human joint replacement corrosion–wear environment

2008 ◽  
Vol 41 (10) ◽  
pp. 105305 ◽  
Author(s):  
P A Dearnley ◽  
C G Figueiredo Pina ◽  
J Fisher
Keyword(s):  
Stainless Steel ◽  
Joint Replacement ◽  
S Phase ◽  
Corrosion Wear ◽  
Human Joint ◽  
Medical Grade

Low-Temperature Plasma Surface Modification of Medical Grade Austenitic Stainless Steel to Combat Wear and Corrosion

2008 ◽  
Vol 373-374 ◽  
pp. 296-299 ◽  
Author(s):  
Joseph P. Buhagiar ◽  
Han Shan Dong
Keyword(s):  
Stainless Steel ◽  
Corrosion Resistance ◽  
Austenitic Stainless Steel ◽  
Low Temperature ◽  
S Phase ◽  
Low Temperature Plasma ◽  
Temperature Plasma ◽  
Phase Layer ◽  
Wear And Corrosion ◽  
Medical Grade

The novel low temperature plasma alloying technique that simultaneously introduces both nitrogen and carbon into the surface of austenitic stainless steel has been used in the past to create a hybrid N-C S-Phase. This S-Phase layer boasts of high hardness and wear resistance without any detriment to corrosion resistance. In this study, the afore mentioned hybrid N-C S-Phase was successfully implemented in the surface of two medical grade austenitic stainless steels: ASTM F138 and F1586. At an optimum process temperature of 430°C a very hard, 20μm precipitate-free S-Phase layer was created. Anodic Polarization tests in Ringer’s solution showed that the corrosion resistance of this layer was similar to that of the untreated alloys. Both dry-wear and corrosion-wear (Ringer’s) behaviour of the surface treated alloys showed an improvement of more than 350% and 40% respectively when compared to the untreated material.

scholarly journals Molecular characterisation of osteoblasts from bone obtained from people of Polynesian and European ancestry undergoing joint replacement surgery

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dorit Naot ◽  
Jarome Bentley ◽  
Cluny Macpherson ◽  
Rocco P. Pitto ◽  
Usha Bava ◽  
...  
Keyword(s):  
Gene Expression ◽  
Real Time ◽  
Joint Replacement ◽  
Real Time Pcr ◽  
S Phase ◽  
European Ancestry ◽  
Mineral Density ◽  
Differentiation Markers ◽  
Joint Replacement Surgery ◽  
Bone Properties

AbstractPopulation studies in Aotearoa New Zealand found higher bone mineral density and lower rate of hip fracture in people of Polynesian ancestry compared to Europeans. We hypothesised that differences in osteoblast proliferation and differentiation contribute to the differences in bone properties between the two groups. Osteoblasts were cultured from bone samples obtained from 30 people of Polynesian ancestry and 25 Europeans who had joint replacement surgeries for osteoarthritis. The fraction of cells in S-phase was determined by flow cytometry, and gene expression was analysed by microarray and real-time PCR. We found no differences in the fraction of osteoblasts in S-phase between the groups. Global gene expression analysis identified 79 differentially expressed genes (fold change > 2, FDR P < 0.1). Analysis of selected genes by real-time PCR found higher expression of COL1A1 and KRT34 in Polynesians, whereas BGLAP, DKK1, NOV, CDH13, EFHD1 and EFNB2 were higher in Europeans (P ≤ 0.01). Osteoblasts from European donors had higher levels of late differentiation markers and genes encoding proteins that inhibit the Wnt signalling pathway. This variability may contribute to the differences in bone properties between people of Polynesian and European ancestry that had been determined in previous studies.

scholarly journals Electropolishing of medical-grade stainless steel in preparation for surface nano-texturing

2011 ◽  
Vol 16 (4) ◽  
pp. 1389-1397 ◽  
Author(s):  
Feroze Nazneen ◽  
Paul Galvin ◽  
Damien W. M. Arrigan ◽  
Michael Thompson ◽  
Pasquale Benvenuto ◽  
...  
Keyword(s):  
Stainless Steel ◽  
Medical Grade
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