Implications of molecular nanotechnology technical performance parameters on previously defined space system architectures

2001 ◽  
Vol 12 (1) ◽  
pp. 84-84
Author(s):  
T L McKendree
2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 139-140
Author(s):  
Frédéric A Vangroenweghe

Abstract Post-weaning Escherichia coli diarrhea (PWD) remains a major cause of economic losses for the pig industry. PWD, caused by enterotoxigenic E. coli (ETEC), typically provokes mild to severe watery diarrhea between 5–10 days after weaning. Recently, an oral live bivalent E. coli F4/F18 vaccine (Coliprotec® F4/F18; Elanco) was approved on the European market, which reduces the impact of PWD provoked by F4-ETEC and F18-ETEC. The objective was to compare technical results and antibiotic use following E. coli F4/F18 vaccination with previous standard therapeutic approach under field conditions. A 1600-sow farm (weaning at 26 days) with diagnosed problems of PWD due to F18-ETEC was selected. Piglets were vaccinated at 21 days with the oral live bivalent E. coli F4/F18 vaccine. At weaning, no standard group medication (ZnO and antibiotics) was applied for prevention of PWD. Several performance parameters were collected: treatment incidence (TI100), mortality and days in nursery. Statistical analysis was performed using JMP 14.0 – comparison of means. Oral E. coli F4/F18 vaccination significantly reduced TI100 (7 ± 2 days to 0 ± 1 days; P < 0.05). Mortality rate remained stable (2.05% in Control to 1.96% in Vaccinated group; P < 0.05). Days in nursery (40 ± 3 days) remained at the same level compared to pre-vaccination. The results show that live E. coli F4/F18 vaccination against PWD has led to similar technical performance parameters and mortality, in combination with a significant reduction in medication use. In conclusion, control of PWD through oral vaccination is a successful option in order to prevent piglets from the negative clinical outcomes of F18-ETEC infection during the post-weaning period.


2019 ◽  
Vol 25 (1) ◽  
pp. 47-52
Author(s):  
Marin-Marian Coman ◽  
Dorel Badea

Abstract Actual scientific approaches related to critical infrastructure reveal its importance within many of the society’s essential services that are necessary for day-to-day people’s life. Besides other critical infrastructure systems, the emerging development of the space system results in the embedment of it within the critical space infrastructure concept that is based on its description related to the importance of the services provided to population, public or governing institutions, and industry. This paper intends to present the manner in which the space system services influence population’s life and to emphasize the importance of the space infrastructure related to the process of planning and conducting military operations. The reliability and well functioning of the space system from the perspective as a critical infrastructure proves its paramount importance related to essential services provided to the population that results into social well-being. Nowadays, the majority of military operations depend on the development of space infrastructure and its reliability. Moreover, the military space operations are based on satellite control system architectures as well as the interconnected systems on surface and underground systems. From this side, the protection of critical space infrastructure and its resilience level should have a paramount value for all stakeholders that are using the space system services.


2019 ◽  
Vol 268 ◽  
pp. 67-72 ◽  
Author(s):  
Elise Vandekerckhove ◽  
Johnny Vlaminck ◽  
Rubén del Pozo Sacristán ◽  
Peter Geldhof

2003 ◽  
Vol 13 (1) ◽  
pp. 1380-1392 ◽  
Author(s):  
Daniel E. Hastings ◽  
Annalisa L. Weigel ◽  
Myles A. Walton

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 138-138
Author(s):  
Frédéric A Vangroenweghe ◽  
Annelies Van Poucke ◽  
Pascal Defoort

Abstract Post-weaning Escherichia coli diarrhea (PWD) remains a major cause of economic losses for the pig industry. PWD, caused by enterotoxigenic E. coli (ETEC), typically provokes mild to severe watery diarrhea between 5 and 10 days after weaning. Recently, an oral live bivalent E. coli F4/F18 vaccine (Coliprotec® F4/F18; Elanco) is available on the European market, which reduces the impact of PWD provoked by F4-ETEC and F18-ETEC. The objective was to compare technical results of E. coli F4/F18 vaccination with previous standard therapeutic approach under field conditions. A 1100-sow farm with diagnosed problems of PWD due to F18-ETEC was selected. Control piglets received the standard treatment protocol with antimicrobials during the post-weaning phase. Vaccinated piglets were immunized at 18 days with the oral live bivalent E. coli F4/ F18 vaccine. At weaning, no standard group medication (ZnO and antibiotics) was applied for prevention of PWD. Piglets were fed a commercial dry feed. Several performance parameters were collected: weight at d0-47, ADWG, ADFI, FCR, TI100 and mortality. Statistical analysis was performed with JMP 14.0 – comparison of means. Oral E. coli F4/F18 vaccination significantly reduced the mortality rate (3.56% to 1.67%; P< 0.05) and TI100 (10 to 0 days; P< 0.05). All other performance parameters (ADWG, ADFI and FCR) were at the same level compared to pre-vaccination. Live E. coli F4/F18 vaccination against PWD resulted in similar technical performance parameters, in combination with a significant reduction in the mortality and medication use. In conclusion, control of PWD through vaccination is a good option in order to prevent piglets from the negative clinical outcomes of F18-ETEC infection during the post-weaning period.


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