Supporting clinical decision making during deep brain stimulation surgery by means of a stochastic dynamical model

2014 ◽  
Vol 11 (5) ◽  
pp. 056019 ◽  
Author(s):  
Sofia D Karamintziou ◽  
George L Tsirogiannis ◽  
Pantelis G Stathis ◽  
George A Tagaris ◽  
Efstathios J Boviatsis ◽  
...  
Keyword(s):  
Decision Making ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Dynamical Model ◽  
Deep Brain Stimulation Surgery ◽  
Deep Brain

Using imaging to identify psychogenic parkinsonism before deep brain stimulation surgery

2012 ◽  
Vol 116 (1) ◽  
pp. 114-118 ◽  
Author(s):  
Michael H. Pourfar ◽  
Chris C. Tang ◽  
Alon Y. Mogilner ◽  
Vijay Dhawan ◽  
David Eidelberg
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Metabolic Networks ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Number Of Patients ◽  
Normal Expression ◽  
Deep Brain Stimulation Surgery ◽  
Deep Brain

The frequency with which patients with atypical parkinsonism and advanced motor symptoms undergo deep brain stimulation (DBS) procedures is unknown. However, the potential exposure of these patients to unnecessary surgical risks makes their identification critical. As many as 15% of patients enrolled in recent early Parkinson disease (PD) trials have been found to lack evidence of a dopaminergic deficit following PET or SPECT imaging. This suggests that a number of patients with parkinsonism who are referred for DBS may not have idiopathic PD. The authors report on 2 patients with probable psychogenic parkinsonism who presented for DBS surgery. They found that both patients had normal caudate and putamen [18F]-fluorodopa uptake on PET imaging, along with normal expression of specific disease-related metabolic networks for PD and multiple system atrophy, a common form of atypical neurodegenerative parkinsonism. The clinical and PET findings in these patients highlight the role of functional imaging in assisting clinical decision making when the diagnosis is uncertain.

scholarly journals The UF Deep Brain Stimulation Cognitive Rating Scale (DBS-CRS): Clinical Decision Making, Validity, and Outcomes

2020 ◽  
Vol 14 ◽  
Author(s):  
Lauren Kenney ◽  
Brittany Rohl ◽  
Francesca V. Lopez ◽  
Jacob A. Lafo ◽  
Charles Jacobson ◽  
...  
Keyword(s):  
Decision Making ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Clinical Decision Making ◽  
Rating Scale ◽  
Clinical Decision ◽  
Deep Brain

scholarly journals Time for a New 3-D Image for Globus Pallidus Internus Deep Brain Stimulation Targeting and Programming

2021 ◽  
pp. 1-5
Author(s):  
Joshua K. Wong ◽  
Justin D. Hilliard ◽  
Vanessa M. Holanda ◽  
Aysegul Gunduz ◽  
Aparna Wagle Shukla ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Globus Pallidus ◽  
Brain Stimulation ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Globus Pallidus Internus ◽  
The Past ◽  
Functional Zones ◽  
Spatial Boundary ◽  
Deep Brain

Deep brain stimulation (DBS) is an effective neuromodulatory therapy for Parkinson’s disease (PD). Early studies using globus pallidus internus (GPi) DBS for PD profiled the nucleus as having two functional zones. This concept disseminated throughout the neuromodulation community as the “GPi triangle”. Although our understanding of the pallidum has greatly evolved over the past 20 years, we continue to reference the triangle in our clinical decision-making process. We propose a new direction, termed the spatial boundary hypothesis, to build upon the 2-dimensional outlook on GPi DBS. We believe an updated 3-D GPi model can produce more consistent, positive patient outcomes.

Deep Brain Stimulation Surgery

2012 ◽  
pp. 903-920
Author(s):  
Ryan Uitti ◽  
Yashiko Baba ◽  
Robert Wharen
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Deep Brain Stimulation Surgery ◽  
Deep Brain
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