scholarly journals Sensitivity and specificity of narrow-band imaging nasoendoscopy compared to histopathology results in patients with suspected nasopharyngeal carcinoma

2017 ◽  
Vol 884 ◽  
pp. 012114
Author(s):  
M Adham ◽  
Z Musa ◽  
Lisnawati ◽  
I Suryati
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Sensitivity And Specificity ◽  
Narrow Band ◽  
Narrow Band Imaging

Use of narrow-band imaging in detection of nasopharyngeal carcinoma

2013 ◽  
Vol 127 (2) ◽  
pp. 163-169 ◽  
Author(s):  
J F Thong ◽  
D Loke ◽  
R Karumathil Sivasankarannair ◽  
P Mok
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Papillary Adenocarcinoma ◽  
Nasopharyngeal Mass ◽  
Surface Patterns ◽  
Brown Centre ◽  
Epstein Barr ◽  
Characteristic Features ◽  
Adenoidal Tissue

AbstractAim:To compare narrow-band images of nasopharyngeal carcinoma with those of normal adenoidal tissue.Method:Patients with a nasopharyngeal mass were evaluated using both conventional white light and narrow-band light. Biopsies were performed and Epstein–Barr viral serology was tested for all patients.Results:Thirty consecutive patients were recruited. Twenty-one patients had normal adenoidal tissue and seven had nasopharyngeal carcinoma. One patient with papillary adenocarcinoma was excluded. The features of narrow-band imaging in normal adenoidal tissue were: (1) a regularly arranged follicular pattern, and (2) each ‘follicle’ comprising a pale centre with surrounding dark periphery. The features of narrow-band imaging in nasopharyngeal carcinoma were: (1) absence of surface patterns (n = 7), and/or (2) ‘reverse’, haphazard follicular pattern comprising a dark brown centre and pale periphery (n = 3).Conclusion:Narrow-band imaging of the surface of adenoidal tissue and nasopharyngeal carcinoma appears to identify distinct, characteristic features as described. Narrow-band imaging may be a useful adjunct in differentiating normal adenoidal tissue from malignancy. Further studies are needed to evaluate its diagnostic accuracy.

Use of Narrow-Band Imaging in Detection of Nasopharyngeal Carcinoma

2011 ◽  
Vol 145 (2_suppl) ◽  
pp. P187-P187
Author(s):  
Jiun Fong Thong ◽  
Karumathil Sivasankarannair Ranjini ◽  
David Loke ◽  
Paul Kan Hwei Mok
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Narrow Band ◽  
Narrow Band Imaging

Endoscopic diagnosis of laryngeal cancer and precancerous lesions by narrow band imaging

2010 ◽  
Vol 125 (3) ◽  
pp. 288-296 ◽  
Author(s):  
X-G Ni ◽  
S He ◽  
Z-G Xu ◽  
L Gao ◽  
N Lu ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Laryngeal Cancer ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Precancerous Lesions ◽  
Type I ◽  
Severe Dysplasia ◽  
Laryngeal Lesions ◽  
Type V

AbstractObjective:To investigate the characteristics of the laryngeal mucosal microvascular network in suspected laryngeal cancer patients, using narrow band imaging, and to evaluate the value of narrow band imaging endoscopy in the early diagnosis of laryngeal precancerous and cancerous lesions.Patients and methods:Eighty-five consecutive patients with suspected precancerous or cancerous laryngeal lesions were enrolled in the study. Endoscopic narrow band imaging findings were classified into five types (I to V) according to the features of the mucosal intraepithelial papillary capillary loops assessed.Results:A total of 104 lesions (45 malignancies and 59 nonmalignancies) was detected under white light and narrow band imaging modes. The sensitivity and specificity of narrow band imaging in detecting malignant lesions were 88.9 and 93.2 per cent, respectively. The intraepithelial papillary capillary loop classification, as determined by narrow band imaging, was closely associated with the laryngeal lesions' histological findings. Type I to IV lesions were considered nonmalignant and type V lesions malignant. For type Va lesions, the sensitivity and specificity of narrow band imaging in detecting severe dysplasia or carcinoma in situ were 100 and 79.5 per cent, respectively. In patients with type Vb and Vc lesions, the sensitivity and specificity of narrow band imaging in detecting invasive carcinoma were 83.8 and 100 per cent, respectively.Conclusion:Narrow band imaging is a promising approach enabling in vivo differentiation of nonmalignant from malignant laryngeal lesions by evaluating the morphology of mucosal capillaries. These results suggest endoscopic narrow band imaging may be useful in the early detection of laryngeal cancer and precancerous lesions.

Narrow band imaging endoscopy of the nasopharynx is not more useful than white light endoscopy for suspected nasopharyngeal carcinoma

2016 ◽  
Vol 273 (10) ◽  
pp. 3363-3369 ◽  
Author(s):  
Alexander C. Vlantis ◽  
John K. S. Woo ◽  
Michael C. F. Tong ◽  
Ann D. King ◽  
William Goggins ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
White Light ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
White Light Endoscopy

The Diagnostic Value of Narrow-Band Imaging for the Detection of Nasopharyngeal Carcinoma

ORL ◽  
2012 ◽  
Vol 74 (5) ◽  
pp. 235-239 ◽  
Author(s):  
Haidi Yang ◽  
Yiqing Zheng ◽  
Qiujian Chen ◽  
Hao Xiong ◽  
Bin Chen ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Diagnostic Value

scholarly journals A meta-analysis of narrow-band imaging for the diagnosis of primary nasopharyngeal carcinoma

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 759 ◽  
Author(s):  
David CM Yeung ◽  
Alexander C Vlantis ◽  
Eddy WY Wong ◽  
Michael CF Tong ◽  
Jason YK Chan
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Likelihood Ratio ◽  
White Light ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Positive Likelihood Ratio ◽  
Negative Likelihood Ratio ◽  
Detection Rates ◽  
White Light Endoscopy ◽  
Significant Difference

Background: Narrow band imaging (NBI), an endoscopic technique featuring an augmented definition of microvasculature and mucosal patterns. NBI is increasingly advocated as a tool to characterize neoplasia and intestinal metaplasia in endoscopic standards, such as for colorectal polyps and tumors. Recently NBI has also been studied in the detection of Nasopharyngeal Carcinoma (NPC). Here we aimed to assess the diagnostic utility of NBI for the diagnosis of NPC. Methods: A meta-analysis of studies comparing narrow-band imaging and white light endoscopy in the diagnosis of primary nasopharyngeal carcinoma was performed. The review process involved two independent investigators. The databases used were MEDLINE, PubMed, the Cochrane library, Embase, and the Web of Science. Statistical analysis was performed with OpenMetaAnalyst, MetaDiSc version 1.4, and Medcalc version 17.9.7.  Results: Five studies including 2480 patients were included. The sensitivity and specificity for narrow-band imaging were 0.90 (0.73-0.97) and 0.95 (0.81-0.99) respectively. The positive likelihood ratio and negative likelihood ratio were 18.82 (0.31-82.1) and 0.08 (0.02-0.31). For white light endoscopy, the sensitivity and specificity were 0.77 (0.58-0.89) and 0.91 (0.79-0.96). The positive likelihood ratio was 7.61 (3.61-16.04), and the negative likelihood ratio was 0.21 (0.11-0.39). The odds ratio for detection rates between narrow-band imaging and white light endoscopy was 4.29 (0.56-33.03, p = 0.16). Area under the curve for narrow-band imaging was 0.98 (SE: 0.02), and for white light it was 0.93 (SE: 0.03). There was no significant difference in the receiver operating characteristic curves between the two modalities (p = 0.14). Conclusion: Narrow-band imaging showed a higher sensitivity and positive likelihood ratio for the diagnosis of nasopharyngeal carcinoma. However, there was no significant difference in detection rates compared to white light endoscopy. Further investigation with a uniform diagnostic criteria and terminology is needed for narrow-band imaging in the diagnosis of nasopharyngeal carcinoma.

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