scholarly journals Optimization of Extraction Process of Valeriana officinalis L. Root Essential Oil and Study on Its Anti-Free Radical Activity

Author(s):  
Tianlin Miao ◽  
Hongjuan Zheng ◽  
Xue Wang ◽  
Ying Lan ◽  
Yuehua Zhang ◽  
...  
2019 ◽  
Vol 17 (1) ◽  
pp. 422-428 ◽  
Author(s):  
Hanoch Julianus Sohilait ◽  
Healthy Kainama

AbstractEssential oil from Eugenia caryophylata was normally used to heal many different deseaces. Various chemical compositions of essential oil distilled and steamed of Moluccas Eugenia caryophylata has been investigated by many different researchers. Even though an intensive research has been carried out of the local chemotypes, a very detail study has not been fully investigated to find out the complete chemical compounds from the plant essential oil and its content associated with their biological activities. In present paper, we assess the free radical scavenging of E. caryophylata collected from Moluccas islands, Indonesia. Essential oil was extracted from leaves, buds, and stems of plant by steam distillation and analyzed using GC-FID and GC-MS. The result showed that free radical activity of essential oil, main constituent and its derivatives were analized using in vitro method. Essential oil activity from stem obtained as (0.82±0.15 μg/mL) was higher than that from bud and leaf possessing both 1,1-diphenyl-2-picrylhydrazyl (DPPH) and (2,2’-azino-bis-3-ethylbenzthizoline-6-sulphonic acid (ABTS) radical scavenging assays by sinergism of eugenol, eugenyl acetate, β-caryophylene and humulene. The activity of isoeugenol (2) (3.59±0.54 μM) and (5.0±0.53 µM) scavenging DPPH and ABTS, respectively, as derivatives eugenol was higher than (3), (4) and (5). Although (6) was active originally, it was inactive after conversion of the ester. While the change of the double bond of location to conjungation structure caused more activity scavenging radicals than the starting molecule.


Diabetes ◽  
1992 ◽  
Vol 41 (8) ◽  
pp. 909-913 ◽  
Author(s):  
A. Collier ◽  
A. Rumley ◽  
A. G. Rumley ◽  
J. R. Paterson ◽  
J. P. Leach ◽  
...  

1991 ◽  
Vol 81 (s25) ◽  
pp. 17P-17P ◽  
Author(s):  
CIA Jack ◽  
MJ Jackson ◽  
E Ridgeway ◽  
CRK Hind

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Oluwakayode O. Odeja ◽  
Michael Gabriel Ibok ◽  
Ejike O. Okpala

Abstract Background Asparagus flagellaris leaves are ethnomedicinally used to treat syphilis, gonorrhea and other sexually transmitted diseases (STDs), with no reports on the volatile constituents. This study was aimed to quantitatively and qualitatively characterise the composition of essential oil, evaluates the free radical scavenging and antimicrobial capacity of the essential oil. Methods The essential oil was isolated by hydrodistillation method using all-glass Clevenger-type apparatus, while the identification and quantification of constituents were performed by gas chromatography-mass spectrometry (GC-MS) technique. The antioxidant activity on 2, 2-diphenyl-1-picrylhydrazyl (DPPH) was evaluated and the oil was also tested against 10 strains of microorganisms consisting of 6 bacteria: Escherichia coli, Salmonella typhi, Klebsiella pneumonia, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis and 4 fungi: Candida albicans, Penicillium notatum, Aspergillus niger and Rhizopus spp. using broth dilution and surface plate methods, respectively. Results A pale yellow essential oil with a characteristic scent was obtained, with a yield of 0.80% (w/w). A total of 28 compounds accounting for 97.41% of the total oil contents were identified. The oil was predominated by Thymol and its derivatives, accounting for 57.48%. The most abundance (% area) constituents of the essential oil were 5-Thymyl tiglate (18.49%), Thymyl-2-methyl butyrate (17.34%), Thymol hydroquinone dimethyl ether (10.52%), Thymol methyl ether (9.42%) and 5-Propyl-1, 3-benzodioxole (4.59%). The essential oil showed a significant free radical scavenging activity compared to the standard antioxidant drugs used in this study, with % inhibition varying from 88.06 ± 0.0001 to 93.05 ± 0.0006. The leaf essential oil exhibited antimicrobial activity on all the tested organisms at 500–125 μg/mL, with an 18–10 mm inhibitory zone. Conclusion The leaf essential oil of A. flagellaris contains notable chemical compounds responsible for its antioxidant and antimicrobial activities.


Gerontology ◽  
1992 ◽  
Vol 38 (5) ◽  
pp. 268-274 ◽  
Author(s):  
A.J. Sinclair ◽  
A.J. Girling ◽  
L. Gray ◽  
J. Lunec ◽  
A.H. Barnett

1994 ◽  
Vol 127 (6) ◽  
pp. 1443-1449 ◽  
Author(s):  
Ever D. Grech ◽  
Christopher M. Bellamy ◽  
Malcolm J. Jackson ◽  
Ronald A. Muirhead ◽  
E.Brian Faragher ◽  
...  

2009 ◽  
Vol 45 (3) ◽  
pp. 469-474 ◽  
Author(s):  
Josiane de Fátima Gaspari Dias ◽  
Obdúlio Gomes Miguel ◽  
Marilis Dallarmi Miguel

The essential oil obtained from flowers of Aster lanceolatus was submitted the CG-MS and presented as result thirteen substances with largest concentration; among them, the caryophyllene oxide with the larger one. The aromatic water obtained during the extraction process of this essential oil was forwarded to allelopathic test, and demonstrated to be capable to inhibit the germination and growth of Lactuca sativa.


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