scholarly journals Continuous assessment of sweat lactic acid secretion using microfluidic sweat lactic acid monitoring system

2021 ◽  
Vol 1192 (1) ◽  
pp. 012006
Author(s):  
Y Goto ◽  
Y Suzuki ◽  
K Morisawa ◽  
A Hosoyama ◽  
Y Taira ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Monitoring System ◽  
Continuous Monitoring ◽  
Carbon Electrodes ◽  
Clinical Tests ◽  
Continuous Assessment ◽  
Lactate Oxidase ◽  
Sampling Device ◽  
Non Invasive ◽  
Phosphate Buffered Saline

Abstract A microfluidic sweat lactic acid (LA) monitoring system for non-invasive and continuous assessment of sweat LA was constructed and tested. Our system transports whole secretions from the skin to an electrochemical LA biosensor using a continuous flow of phosphate buffered saline at the skin’s surface. The LA biosensor was fabricated by modifying screen printed carbon electrodes with osmium wired horseradish peroxidase and lactate oxidase. For continuous monitoring purposes, the microfluidic LA biosensor was connected with a flow cell made of polydimethylsiloxane (PDMS). The sampling device was fabricated by laminating a medical plaster on a PDMS flow-channel. Before the clinical tests, the characteristics of the LA biosensor were evaluated. Sufficient sensitivity (0.4232 nA/µM) and selectivity to LA (> 50fold against glucose, glutamic acid, phenylalanine, ammonia and ethanol) were confirmed. Besides, the medical plaster-based attachment contributed to the reduced leakage between the skin and the sampling device. Under the approval of the ethical committees, LA monitoring of patients with cardiovascular disease at the intensive care unit was carried out. As a result, temporal changes of sweat LA were successfully monitored.

Non-invasive endocrine assessments in the domestic sow: towards an automated reproductive monitoring system for pig production

2004 ◽  
Vol 31 ◽  
pp. 169-174
Author(s):  
A. R. Pickard ◽  
J. M. Vazquez ◽  
R. M. Pemberton ◽  
J. P. Hart ◽  
T. T. Mottram
Keyword(s):  
Monitoring System ◽  
Vascular Access ◽  
Sampling Period ◽  
Automated System ◽  
Sampling Device ◽  
Access Port ◽  
Non Invasive ◽  
Saliva Collection ◽  
Hormone Analysis ◽  
Entire Sampling Period

AbstractA method for monitoring the reproductive status of female pigs, using non–invasive hormone analysis was developed. Plasma and saliva samples were collected from five reproductively active sows, and analysed for oestradiol–17ß and progesterone by immunoassay. The oestradiol–17ß content of the saliva samples was also measured using a novel biosensor–based method to demonstrate, in principle, the potential to develop an automated system for hormone analysis and interpretation. A hand–held saliva sampling device was designed and built for the purpose of this experiment. Plasma and saliva samples were collected for 3.5 months from four of the five sows. The vascular access port implanted into the fifth sow failed; therefore she could only be used for saliva collection. Saliva sampling was 100% successful for the first two weeks of the study. Over the entire sampling period, daily and twice weekly samples could be collected on 86% of the attempts made. Both progesterone and oestradiol–17ß were measured in saliva samples using conventional immunoassay techniques.

INVESTIGATION OF HAND KINEMATICS TOWARDS FRONT CRAWL SWIMMING USING NON-INVASIVE REAL-TIME MONITORING SYSTEM

2014 ◽  
Author(s):  
Rozaimi Ghazali ◽  
◽  
Asiah Mohd Pilus ◽  
Wan Mohd Bukhari Wan Daud ◽  
Mohd Juzaila Abd Latif ◽  
...  
Keyword(s):  
Real Time ◽  
Monitoring System ◽  
Real Time Monitoring ◽  
Front Crawl ◽  
Non Invasive ◽  
Hand Kinematics

scholarly journals Evaluating the Possibility of Translating Technological Advances in Non-Invasive Continuous Lactate Monitoring into Critical Care

Sensors ◽  
2021 ◽  
Vol 21 (3) ◽  
pp. 879
Author(s):  
Robert D. Crapnell ◽  
Ascanio Tridente ◽  
Craig E. Banks ◽  
Nina C. Dempsey-Hibbert
Keyword(s):  
Critical Care ◽  
Continuous Monitoring ◽  
Performance Monitoring ◽  
Plasma Concentrations ◽  
Lactate Production ◽  
Anaerobic Exercise ◽  
Response To Treatment ◽  
Diverse Range ◽  
Non Invasive ◽  
Technological Advances

Lactate is widely measured in critically ill patients as a robust indicator of patient deterioration and response to treatment. Plasma concentrations represent a balance between lactate production and clearance. Analysis has typically been performed with the aim of detecting tissue hypoxia. However, there is a diverse range of processes unrelated to increased anaerobic metabolism that result in the accumulation of lactate, complicating clinical interpretation. Further, lactate levels can change rapidly over short spaces of time, and even subtle changes can reflect a profound change in the patient’s condition. Hence, there is a significant need for frequent lactate monitoring in critical care. Lactate monitoring is commonplace in sports performance monitoring, given the elevation of lactate during anaerobic exercise. The desire to continuously monitor lactate in athletes has led to the development of various technological approaches for non-invasive, continuous lactate measurements. This review aims firstly to reflect on the potential benefits of non-invasive continuous monitoring technology within the critical care setting. Secondly, we review the current devices used to measure lactate non-invasively outside of this setting and consider the challenges that must be overcome to allow for the translation of this technology into intensive care medicine. This review will be of interest to those developing continuous monitoring sensors, opening up a new field of research.

scholarly journals Methodology: non-invasive monitoring system based on standing wave ratio for detecting water content variations in plants

Plant Methods ◽  
2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Yunjeong Yang ◽  
Ji Eun Kim ◽  
Hak Jin Song ◽  
Eun Bin Lee ◽  
Yong-Keun Choi ◽  
...  
Keyword(s):  
Water Content ◽  
Monitoring System ◽  
Standing Wave ◽  
Magnetic Particles ◽  
Experimental Plant ◽  
Invasive Monitoring ◽  
Monitoring Method ◽  
Non Invasive ◽  
Content Variation ◽  
Stem Water

Abstract Background Water content variation during plant growth is one of the most important monitoring parameters in plant studies. Conventional parameters (such as dry weight) are unreliable; thus, the development of rapid, accurate methods that will allow the monitoring of water content variation in live plants is necessary. In this study, we aimed to develop a non-invasive, radiofrequency-based monitoring system to rapidly and accurately detect water content variation in live plants. The changes in standing wave ratio (SWR) caused by the presence of stem water and magnetic particles in the stem water flow were used as the basis of plant monitoring systems. Results The SWR of a coil probe was used to develop a non-invasive monitoring system to detect water content variation in live plants. When water was added to the live experimental plants with or without illumination under drought conditions, noticeable SWR changes at various frequencies were observed. When a fixed frequency (1.611 GHz) was applied to a single experimental plant (Radermachera sinica), a more comprehensive monitoring, such as water content variation within the plant and the effect of illumination on water content, was achieved. Conclusions Our study demonstrated that the SWR of a coil probe could be used as a real-time, non-invasive, non-destructive parameter for detecting water content variation and practical vital activity in live plants. Our non-invasive monitoring method based on SWR may also be applied to various plant studies.

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