Cardiovascular Diseases (CVDs) are one of the foremost causes of deaths across the world. This review aims to evaluate the genetics and risk factors involved in CVDs and to assess the preventive measures which can be taken for diminishing the chances of developing CVDs. The goal of this review is to provide researchers and clinicians dealing with vascular disorders with a compendium of data about the genetic causes, risk factors, and preventive strategies to combat the development of CVDs. We searched online databases including PubMed for peer-reviewed scientific papers, case studies and review articles related to CVDs, emphasizing on the role of genetics and risk factors like diabetes, hypertension, smoking, alcohol consumption, obesity, age & gender in the progression of CVDs, and reviewing the role of diet and exercise in the prevention of CVDs. Managing the risk factors involved in CVDs is the most essential step for the inhibition of vascular diseases. Healthy lifestyle interventions consisting of a well-balanced diet and physical activity are very critical for the prevention of CVDs. Trials carried out on model organisms have indicated a direct link between diet and exercise on cardiovascular conditions. Strategies involved in the treatment of vascular diseases should also include low-fat diet plans like consumption of whole grains, fruits, vegetables, yogurts and avoiding high-saturated fat-containing foods with the addition of performing moderate aerobic exercises including cycling, swimming, hiking, and running to eliminate the root of the problem.
Role of SIRT1-FoxO1 Signaling in Dietary Saturated Fat-Dependent Upregulation of Liver Adiponectin Receptor 2 in Ethanol-Administered Mice
