scholarly journals Thermal Treatment Options for Benign Thyroid Nodules—The Role of Radio-Frequency Ablation and Laser Therapy

2021 ◽  
Vol 33 (1) ◽  
pp. 17-20
Author(s):  
Erivelto Volpi
Keyword(s):  
Thermal Treatment ◽  
Radio Frequency ◽  
Laser Therapy ◽  
Thyroid Nodules ◽  
Treatment Options ◽  
Radio Frequency Ablation ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

Virtually-tracked US-guided radio frequency ablation of benign thyroid nodules: preliminary evaluation

2014 ◽  
Author(s):  
Laura Camerieri ◽  
Giovanni Turtulici ◽  
Angelo Corazza ◽  
Simone Schiaffino ◽  
Riccardo Sartoris ◽  
...  
Keyword(s):  
Radio Frequency ◽  
Thyroid Nodules ◽  
Radio Frequency Ablation ◽  
Preliminary Evaluation ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

What Is the Role of Radiofrequency Ablation for Benign Thyroid Nodules?

2021 ◽  
Author(s):  
Peter Horwich ◽  
Brent A. Chang ◽  
Ameya A. Asarkar ◽  
Gregory W. Randolph ◽  
Cherie‐Ann O. Nathan
Keyword(s):  
Radiofrequency Ablation ◽  
Thyroid Nodules ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

scholarly journals Benign Aspirates on Follow-Up FNA May Be Enough in Patients with Initial Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Ga Ram Kim ◽  
Jung Hyun Yoon ◽  
Eun-Kyung Kim ◽  
Hee Jung Moon ◽  
Jin Young Kwak
Keyword(s):  
Thyroid Nodules ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Risk Of Malignancy ◽  
Benign Nodules ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid ◽  
Undetermined Significance

Background.Management of thyroid nodules with benign aspirates following atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) is not well established. We reviewed the risk of malignancy and the role of ultrasound (US) features among thyroid nodules with benign results following initial AUS/FLUS diagnoses.Methods.From December 2009 to February 2011, a total of 114 nodules in 114 patients diagnosed as benign on follow-up fine-needle aspiration (FNA) after AUS/FLUS results were included in our study. Eight among 114 nodules were confirmed pathologically and 106 were clinically observed by a follow-up FNA or US. Suspicious US features were defined as markedly hypoechogenicity, irregular or microlobulated margin, presence of microcalcifications, and taller than wide shape.Results.There were 110 (96.5%) benign nodules and 4 (3.5%) malignant nodules. Two (4.8%) among 42 nodules without suspicious US features and 2 (2.8%) out of 72 nodules with suspicious US features were confirmed as malignancy, but there were no significant associations between the malignancy rate and US features (P=0.625).Conclusion.Clinical follow-up instead of surgical excision or continuous repeat FNA may be enough for benign thyroid nodules after AUS/FLUS. The role of US features might be insignificant in the management of these nodules.

scholarly journals Role of Duplex Power Doppler Ultrasound in Differentiation between Malignant and Benign Thyroid Nodules

2010 ◽  
Vol 11 (6) ◽  
pp. 594 ◽  
Author(s):  
Oktay Algin ◽  
Efnan Algin ◽  
Gokhan Gokalp ◽  
Gokhan Ocakoğlu ◽  
Cüneyt Erdoğan ◽  
...  
Keyword(s):  
Doppler Ultrasound ◽  
Thyroid Nodules ◽  
Power Doppler ◽  
Power Doppler Ultrasound ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

scholarly journals Role of cytological characteristics of benign thyroid nodules on effectiveness of their treatment with levothyroxine

2013 ◽  
Vol 6 ◽  
pp. 1083-1089
Author(s):  
Mustafa Cesu ◽  
Mehtap Akcil ◽  
Sibel Ertek ◽  
Rifat Emral ◽  
Safak Bulut ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
Cytological Characteristics ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

Evidence-Based Assessment of the Role of Ultrasonography in the Management of Benign Thyroid Nodules

2008 ◽  
Vol 32 (7) ◽  
pp. 1253-1263 ◽  
Author(s):  
Lilah F. Morris ◽  
Nagesh Ragavendra ◽  
Michael W. Yeh
Keyword(s):  
Thyroid Nodules ◽  
Evidence Based ◽  
Benign Thyroid Nodules ◽  
Benign Thyroid

scholarly journals The Mitochondrial DNA Control Region might have useful Diagnostic and Prognostic Biomarkers for Thyroid Tumors

2018 ◽  
Author(s):  
Rifat Bircan ◽  
Hülya Iliksu Gözü ◽  
Ulu Esra ◽  
Şükran Sarikaya ◽  
Aylin Ege Gül ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Somatic Mutations ◽  
Thyroid Nodules ◽  
Turkish Population ◽  
Thyroid Tumor ◽  
Thyroid Tumors ◽  
Benign Thyroid Nodules ◽  
Cold Thyroid Nodules ◽  
Benign Thyroid

AbstractBackgroundIt is currently present in the literature that mitochondrial DNA (mtDNA) defects are associated with a great number of diseases including cancers. The role of mitochondrial DNA (mtDNA) variations in the development of thyroid cancer is a highly controversial topic. In this study, we investigated the role of mt-DNA control region (CR) variations in thyroid tumor progression and the influence of mtDNA haplogroups on susceptibility to thyroid tumors.Material & methodFor this purpose, totally 108 hot thyroid nodules (HTNs), 95 cold thyroid nodules (CTNs), 48 papillary thyroid carcinoma (PTC) samples with their surrounding tissues and 104 healthy control subject’s blood samples were screened for entire mtDNA CR variations by using Sanger sequencing. The obtained DNA sequences were anaysed with the mistomaster, a web-based bioinformatics tool.ResultsMtDNA haplogroup U was significantly associated with susceptibility to benign and malign thyroid entities on the other hand J haplogroup was associated with a protective role for benign thyroid nodules. Besides, 8 SNPs (T146C, G185A, C194T, C295T, G16129A, T16304C, A16343G and T16362C) in mtDNA CR region were associated with the occurrence of benign and malign thyroid nodules in Turkish population. By contrast with the healthy Turkish population and HTNs, frequency of C7 repeats in D310 polycytosine sequence was found higher in cold thyroid nodules and PTC samples. Beside this, the frequency of somatic mutations in mtMSI regions including T16189C and D514 CA dinucleotide repeats were found higher in PTC samples than the benign thyroid nodules. Conversely, the frequency of somatic mutations in D310 was detected higher in HTNs than CTNs and PTCs.ConclusionmtDNA D310 instability do not play a role in tumorogenesis of the PTC but the results indicates that it might be used as a diagnostic clonal expansion biomarker for premalignant thyroid tumor cells. Beside this, D514 CA instability might be used as prognostic biomarker in PTCs. Also, we showed that somatic mutation rate is less frequent in more aggressive tumors when we examined micro- and macro carcinomas as well as BRAFV600E mutation.

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