Acellular Human Amniotic Membrane Scaffold with 15d-PGJ2 Nanoparticles in Postinfarct Rat Model

2020 ◽  
Vol 26 (21-22) ◽  
pp. 1128-1137
Author(s):  
Julio Cesar Francisco ◽  
Laercio Uemura ◽  
Rossana Baggio Simeoni ◽  
Ricardo Correa da Cunha ◽  
Bassam Felipe Mogharbel ◽  
...  
Keyword(s):  
Amniotic Membrane ◽  
Rat Model ◽  
Human Amniotic Membrane ◽  
Membrane Scaffold

scholarly journals Bone-Marrow Stem Cells and Acellular Human Amniotic Membrane in a Rat Model of Heart Failure

Life ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 958
Author(s):  
Gustavo Gavazzoni Blume ◽  
Paulo André Bispo Machado-Junior ◽  
Rossana Baggio Simeoni ◽  
Giovana Paludo Bertinato ◽  
Murilo Sgarbossa Tonial ◽  
...  
Keyword(s):  
Heart Failure ◽  
Stem Cells ◽  
Bone Marrow ◽  
Amniotic Membrane ◽  
Rat Model ◽  
Connexin 43 ◽  
Left Ventricular ◽  
Bone Marrow Stem Cells ◽  
Control Group ◽  
Human Amniotic Membrane

Myocardial infarction (MI) remains the leading cause of cardiovascular death worldwide and a major cause of heart failure. Recent studies have suggested that cell-based therapies with bone marrow stem cells (BMSC) and human amniotic membrane (hAM) would recover the ventricular function after MI; however, the mechanisms underlying these effects are still controversial. Herein, we aimed to compare the effects of BMSC and hAM in a rat model of heart failure. MI was induced through coronary occlusion, and animals with an ejection fraction (EF) < 50% were included and randomized into three groups: control, BMSC, and hAM. The BMSC and hAM groups were implanted on the anterior ventricular wall seven days after MI, and a new echocardiographic analysis was performed on the 30th day, followed by euthanasia. The echocardiographic results after 30 days showed significant improvements on EF and left-ventricular end-sistolic and end-diastolic volumes in both BMSC and hAM groups, without significant benefits in the control group. New blood vessels, desmine-positive cells and connexin-43 expression were also elevated in both BMSC and hAM groups. These results suggest a recovery of global cardiac function with the therapeutic use of both BMSC and hAM, associated with angiogenesis and cardiomyocyte regeneration after 30 days.

The Positive Effects of the Human Amniotic Membrane on the Healing of Staple Line After Sleeve Gastrectomy Applied Long-Evans Rat Model

2019 ◽  
Vol 29 (11) ◽  
pp. 3560-3568
Author(s):  
Murat Ferhat Ferhatoglu ◽  
Taner Kıvılcım ◽  
Kazım Senol ◽  
Gurcan Vural ◽  
Abdulcabbar Kartal ◽  
...  
Keyword(s):  
Sleeve Gastrectomy ◽  
Amniotic Membrane ◽  
Rat Model ◽  
Staple Line ◽  
Human Amniotic Membrane ◽  
Positive Effects ◽  
Long Evans

scholarly journals 15d-PGJ2-loaded in nanoparticles associated with decellurazied human amniotic membrane scaffold: A potential anti-inflammatory delivery system

2016 ◽  
Vol 2 (2) ◽  
pp. 111-113 ◽  
Author(s):  
Julio Cesar Francisco ◽  
Bassam Felipe Mogharbel ◽  
Ricardo Cunha ◽  
Marco André Cardoso ◽  
Rossana Baggio Simeoni ◽  
...  
Keyword(s):  
Delivery System ◽  
Amniotic Membrane ◽  
Human Amniotic Membrane ◽  
Anti Inflammatory ◽  
Membrane Scaffold

scholarly journals Bladder Reconstruction with Human Amniotic Membrane in a Xenograft Rat Model: A Preclinical Study

2017 ◽  
Vol 14 (4) ◽  
pp. 310-318 ◽  
Author(s):  
Dimitri Barski ◽  
Holger Gerullis ◽  
Thorsten Ecke ◽  
Jin Yang ◽  
Gabriella Varga ◽  
...  
Keyword(s):  
Amniotic Membrane ◽  
Rat Model ◽  
Preclinical Study ◽  
Human Amniotic Membrane ◽  
Bladder Reconstruction

A bioartificial surgical patch from multilayered human amniotic membrane-In vivoinvestigations in a rat model

2009 ◽  
Vol 90B (2) ◽  
pp. 930-938 ◽  
Author(s):  
Marco Rainer Kesting ◽  
Klaus-Dietrich Wolff ◽  
Thomas Mücke ◽  
Cedric Demtroeder ◽  
Kilian Kreutzer ◽  
...  
Keyword(s):  
Amniotic Membrane ◽  
Rat Model ◽  
Human Amniotic Membrane

Effect of viable cryopreserved human amniotic membrane sutured to cornea on course of experimental bacterial keratitis

2015 ◽  
Vol 57 (5) ◽  
pp. 35-41
Author(s):  
K. Sereda ◽  
◽  
G. Drozhzhina ◽  
T. Gaidamaka ◽  
V. Vit ◽  
...  
Keyword(s):  
Amniotic Membrane ◽  
Human Amniotic Membrane ◽  
Bacterial Keratitis

scholarly journals Human Amniotic Membrane as a Matrix for Endothelial Differentiation of VEGF-Treated Dental Stem Cells

2019 ◽  
Vol 12 (6) ◽  
pp. 599-613 ◽  
Author(s):  
Siti Nurnasihah Md Hashim ◽  
Muhammad Fuad Hilmi Yusof ◽  
Wafa’ Zahari ◽  
Hamshawagini Chandra ◽  
Khairul Bariah Ahmad Amin Noordin ◽  
...  
Keyword(s):  
Stem Cells ◽  
Amniotic Membrane ◽  
Endothelial Differentiation ◽  
Human Amniotic Membrane ◽  
Dental Stem Cells
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