Soluble Scavenger Receptor CD163 Is Associated with Severe Acute Kidney Injury in Patients with Hantaan Virus Infection

2015 ◽  
Vol 28 (4) ◽  
pp. 241-246 ◽  
Author(s):  
Yusi Zhang ◽  
Ying Ma ◽  
Chunmei Zhang ◽  
Yun Zhang ◽  
Ran Zhuang ◽  
...  
2013 ◽  
Vol 24 (9) ◽  
pp. 781-786
Author(s):  
Takeo Matsuyoshi ◽  
Yasusei Okada ◽  
Hiroshi Inagawa ◽  
Naoki Kojima ◽  
Kazumasa Yamaguchi ◽  
...  

2020 ◽  
Author(s):  
Fengqi Qiu ◽  
Congcong Li ◽  
Jianya Zhou

Abstract Background Hemorrhagic fever with renal syndrome (HFRS) is caused by hantaviruses presenting with high fever, hemorrhage, acute kidney injury. Microvascular injury and hemorrhage in mucus was often observed in patients with hantavirus infection. Infection with bacterial and virus related aortic aneurysm or dissection occurs sporadically. We present a previously unreported case of hemorrhagic fever with concurrent Stanford B aortic dissection. Case presentation: A 56-year-old man complained of high fever, generalized body ache, with decreased platelet counts of 10 × 10^9/L and acute kidney injury. The ELISA test for Hantaan virus of IgM and IgG antibodies were both positive. During the convalescent period, he complained sudden onset acute chest pain radiating to the back and the CTA revealed an aortic dissection of the descending aorta extending to iliac artery. He was diagnosed with Hemorrhagic fever with renal syndrome and Stanford B aortic dissection. The patient recovered completely after surgery with other support treatments. Conclusion We present a case of HFRS complicated with aortic dissection,and no study has reported the association of HFRS with aortic disease. However, we suppose that hantavirus infection not only cause microvascular damage but may be risk factor for acute macrovascular detriment. A causal relationship has yet to be confirmed.


2019 ◽  
Vol 34 (Supplement_1) ◽  
Author(s):  
Isidro Torregrosa ◽  
Ma Solis ◽  
Carmen Ramos ◽  
Aurora Perez-Ys ◽  
Andrea Muijsenberg ◽  
...  

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