scholarly journals Biochemical effects of calcium supplementation in postmenopausal women: influence of dietary calcium intake

1998 ◽  
Vol 67 (6) ◽  
pp. 1273-1278 ◽  
Author(s):  
P Fardellone ◽  
M Brazier ◽  
S Kamel ◽  
J Guéris ◽  
A M Graulet ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Calcium Intake ◽  
Calcium Supplementation ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Biochemical Effects

scholarly journals Dietary Calcium Intake and Calcium Supplementation in Hungarian Patients with Osteoporosis

2013 ◽  
Vol 2013 ◽  
pp. 1-8
Author(s):  
Gábor Speer ◽  
Pál Szamosujvári ◽  
Péter Dombai ◽  
Katalin Csóré ◽  
Kinga Mikófalvi ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Calcium Intake ◽  
Calcium Supplementation ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Current Recommendation ◽  
High Calcium Intake ◽  
Osteoporosis Therapy ◽  
Average Intake ◽  
High Calcium

Purpose. Adequate calcium intake is the basis of osteoporosis therapy—when this proves insufficient, even specific antiosteoporotic agents cannot exert their actions properly.Methods. Our representative survey analyzed the dietary intake and supplementation of calcium in 8033 Hungarian female and male (mean age: 68 years) (68.01 (CI95: 67.81–68.21)) patients with osteoporosis.Results. Mean intake from dietary sources was665±7.9 mg (68.01 (CI95: 67.81–68.21)) daily. A significant positive relationship could be detected between total dietary calcium intake and lumbar spine BMD (P=0.045), whereas such correlation could not be demonstrated with femoralT-score. Milk consumption positively correlated with femur (P=0.041), but not with lumbar BMD. The ingestion of one liter of milk daily increased theT-score by 0.133. Average intake from supplementation was558±6.2 mg (68.01 (CI95: 67.81–68.21)) daily. The cumulative dose of calcium—from both dietary intake and supplementation—was significantly associated with lumbar (r=0.024,P=0.049), but not with femur BMD (r=0.021,P=0.107). The currently recommended 1000–1500 mg total daily calcium intake was achieved in 34.5% of patients only. It was lower than recommended in 47.8% of the cases and substantially higher in 17.7% of subjects.Conclusions. We conclude that calcium intake in Hungarian osteoporotic patients is much lower than the current recommendation, while routinely applied calcium supplementation will result in inappropriately high calcium intake in numerous patients.

scholarly journals Effects of dietary calcium intake on body weight and prevalence of osteoporosis in early postmenopausal women

2007 ◽  
Vol 86 (3) ◽  
pp. 639-644 ◽  
Author(s):  
Massimo Varenna ◽  
Lucia Binelli ◽  
Silvia Casari ◽  
Francesca Zucchi ◽  
Luigi Sinigaglia
Keyword(s):  
Body Weight ◽  
Postmenopausal Women ◽  
Calcium Intake ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Early Postmenopausal Women ◽  
Prevalence Of Osteoporosis

scholarly journals Dietary Calcium Intake and Bone Loss Over 6 Years in Osteopenic Postmenopausal Women

2019 ◽  
Vol 104 (8) ◽  
pp. 3576-3584 ◽  
Author(s):  
Sarah M Bristow ◽  
Anne M Horne ◽  
Greg D Gamble ◽  
Borislav Mihov ◽  
Angela Stewart ◽  
...  
Keyword(s):  
Bone Loss ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Calcium Intake ◽  
Controlled Trial ◽  
Hormone Replacement ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Mineral Density ◽  
Total Body

Abstract Context Calcium intakes are commonly lower than the recommended levels, and increasing calcium intake is often recommended for bone health. Objective To determine the relationship between dietary calcium intake and rate of bone loss in older postmenopausal women. Participants Analysis of observational data collected from a randomized controlled trial. Participants were osteopenic (hip T-scores between −1.0 and −2.5) women, aged >65 years, not receiving therapy for osteoporosis nor taking calcium supplements. Women from the total cohort (n = 1994) contributed data to the analysis of calcium intake and bone mineral density (BMD) at baseline, and women from the placebo group (n = 698) contributed data to the analysis of calcium intake and change in BMD. BMD and bone mineral content (BMC) of the spine, total hip, femoral neck, and total body were measured three times over 6 years. Results Mean calcium intake was 886 mg/day. Baseline BMDs were not related to quintile of calcium intake at any site, before or after adjustment for baseline age, height, weight, physical activity, alcohol intake, smoking status, and past hormone replacement use. There was no relationship between bone loss and quintile of calcium intake at any site, with or without adjustment for covariables. Total body bone balance (i.e., change in BMC) was unrelated to an individuals’ calcium intake (P = 0.99). Conclusions Postmenopausal bone loss is unrelated to dietary calcium intake. This suggests that strategies to increase calcium intake are unlikely to impact the prevalence of and morbidity from postmenopausal osteoporosis.

Dietary calcium, defective cellular Ca2+ handling, and arterial pressure control

1994 ◽  
Vol 72 (8) ◽  
pp. 937-944 ◽  
Author(s):  
David A. McCarron ◽  
Daniel Hatton ◽  
Jean-Baptiste Roullet ◽  
Chantal Roullet
Keyword(s):  
Blood Pressure ◽  
Clinical Trials ◽  
Calcium Intake ◽  
Inverse Relationship ◽  
Spontaneously Hypertensive Rat ◽  
Calcium Supplementation ◽  
Dietary Calcium ◽  
Calcium Handling ◽  
Dietary Calcium Intake ◽  
Experimental Hypertension

The association between dietary calcium intake, calcium metabolism, and blood pressure form the basis of this review. Epidemiologic data consistently show an inverse relationship between dietary calcium and blood pressure. Clinical trials of calcium supplementation have not been as consistent in outcome. Approximately two-thirds of the supplementation studies have found a beneficial effect of calcium on blood pressure. The lack of consistency in outcome from the clinical trials relative to the epidemiological literature may be related to calcium intake. The epidemiological literature indicates an inverse relationship between calcium intake and blood pressure, with those individuals with the lowest calcium intake (< 700 mg/day) having the highest blood pressure. Clinical studies utilizing patients with high baseline calcium levels (> 700 mg/day) may not see an effect of calcium supplementation on blood pressure because of a ceiling effect. Supplemental calcium appears to correct a defect in calcium handling characterized by a renal calcium leak, increased circulating parathroid hormone, and increased intracellular calcium levels. In part, the deficit in cellular calcium homeostasis may be a consequence of abnormal calmodulin activity. Specifically, it appears that calmodulin activity is diminished in experimental hypertension and that increasing dietary calcium may improve calmodulin activity in the spontaneously hypertensive rat. The deficit in calmodulin activity has the potential to interfere with a number of cellular processes crucial to the regulation of cell function and maintenance of appropriate vascular tone. It is concluded that additional research should be directed toward understanding the ramifications of altered calmodulin activity in hypertension and the influence that dietary calcium can have on the activity of calmodulin.Key words: hypertension, dietary Ca2+, calmodulin, Ca2+ metabolism, calcium channel blockers.

scholarly journals Dietary Calcium Intake, Vitamin D Status, and Bone Health in Postmenopausal Women in Rural Pakistan

2011 ◽  
Vol 29 (5) ◽  
Author(s):  
Nicola M Lowe ◽  
Basma Ellahi ◽  
Qudsia Bano ◽  
Sonia Ali Bangash ◽  
Soma R Mitra ◽  
...  
Keyword(s):  
Vitamin D ◽  
Postmenopausal Women ◽  
Bone Health ◽  
Calcium Intake ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Vitamin D Status ◽  
Rural Pakistan
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